Cisplatin-induced inhibition of the calcium-calmodulin complex, neuronal nitric oxide synthase activation and their role in stomach distention

Cancer Chemotherapy and Pharmacology

Volumn 39, Issue 4, 1997, Pages 341-348

  Jarve, Robert K ^a,b   Aggarwal, Surinder K ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium calmodulin complex; Cisplatin; Emesis; Neuronal nitric oxide synthase; Stomach distention

Indexed keywords

CALCIUM; CALMODULIN; CISPLATIN; CITRULLINE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; IMMUNOHISTOCHEMISTRY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH DISTENSION; STOMACH MOTILITY;

ANIMALS; ANTINEOPLASTIC AGENTS; CALCIUM; CALMODULIN; CISPLATIN; CITRULLINE; ENZYME ACTIVATION; FEMALE; MALE; MUSCLE, SMOOTH; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; STOMACH;

EID: 0031024843     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050581     Document Type: Article

References (40)

1. Aggarwal SK (1993) A histochemical approach to the mechanism of action of cisplatin and its analogues. J Histochem Cytochem 41: 1053
2. Aggarwal SK, Fadool JM (1993) Cisplatin and carboplatin induced changes in the neurohypophysis and parathyroid, and their role in nephrotoxicity. Anticancer Drugs 4: 149
3. Aggarwal SK, Broomhead JA, Fairlie DP, Whitehouse MW (1980) Platinum drugs: combined anti-lymphoproliferative and nephrotoxicity assay in rats. Cancer Chemother Pharmacol 4: 249
4. Aggarwal SK, Antonio JDS, Sokhansanj A, Miller CM (1994) Cisplatin induced peptic ulcer, vagotomy adrenal and calcium modulation. Anticancer Drugs 5: 177
5. Andrews P, Howell S (1990) Cellular pharmacology of cisplatin: perspectives on mechanism of acquired resistance. Cancer Cells 2: 35
6. Bajt ML, Aggarwal SK (1985) An analysis of factors responsible for resorption of embryos in cisplatin-treated rats. Toxicol Appl Pharmacol 80: 97
7. Bompart G (1989) Cisplatin-induced changes in cytochrome P-450, lipid peroxidation and drug-metabolizing enzyme activities in rat kidney cortex. Toxicol Lett 48: 193
8. Chao SH, Suzuki Y, Zysk JR, Cheung WY (1984) Activation of calmodulin by various metal cations as a function of ionic radius. Mol Pharmacol 26: 75
9. Choksi A, Hong WK (1987) Chemotherapy of head and neck cancer. In: Nicolini M (ed) Platinum and other metal coordination compounds in cancer chemotherapy. Martinus Nijhoff Publishing, Padua, p 375
10. Cobbs CS, Brenman JE, Aldape KD, Bredt DS, Israel MA (1995) Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res 55: 727
11. Comis RL (1994) Cisplatin: the future. Semin Oncol 21: 109
12. Douple EB (1985) Cis-Diamminedichloroplatinum (II): effects of a representative metal coordination complex on mammalian cells. In: Dethlefsen LA (ed) Cell cycle effects of drugs. Pergamon Press, New York, p 215
13. Einhorn LH, Williams SD (1980) Chemotherapy of disseminated testicular cancer. Cancer 46: 1339
14. Fan S, Smith ML, Rivet DJN, Duba D, Zhan Q, Kohn KW, Fornace AJJ, O'Connor PM (1995) Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifyl-line. Cancer Res 55: 1649
15. Hacker MP, Roberts JD (1987) Cisplatin efficacy and toxicity: are they separable? In: Nicolini M (ed) Platinum and other metal coordination compounds in cancer chemotherapy. Martinus Nijhoff Publishing, Padua, p 163
16. Hahn KH, Waggoner AS, Taylor DL (1990) A calcium-sensitive fluorescent analog of calmodulin based on a novel calmodulin-binding fluorophore. J Biol Chem 265: 20335
17. Huang PL, Dawson TM (1993) Targeted disruption of the neuronal nitric oxide synthase gene. Cell 75: 1273
18. Jennerwein M, Andrews PA (1995) Effect of intracellular chloride on the cellular pharmacodynamics of cis-diamminedichloroplatinum (II). Drug Metab Dispos 23: 178
19. 2+, and the hydrolysis product of cisplatin in the rat. Cancer Chemother Pharmacol 29: 29
20. Jurga L, Misurova E, Kovac V, Sevcikova L (1994) The role of cisplatin in chemotherapy of advanced breast cancer. Neoplasma 41: 347
21. Keller KA, Aggarwal SK (1983) Embryotoxicity of cisplatin in rats and mice. Toxicol Appl Pharmacol 69: 245
22. Kendell ER, Schwartz JH, Jessell TM (1991) Principles in neural science, 3rd ed. Appleton and Lange, Norwalk
23. 2+ and target proteins. In: Cohen P, Klee CB (eds) Calmodulin. Elsevier, Amsterdam New York Oxford, p 35
24. Kris MG, Gralla RJ, Clark RA, Tyson LB, O'Connell JP, Wetheim MS. Kelsen DP (1985) Incidence, course and severity of delayed nausea and vomiting following the administration of high dose cisplatin. J Clin Oncol 3: 1379
25. Litterst CL, Schweitzer VG (1987) Covalent Binding of platinum to kidney subcellular fractions from guinea pig strains sensitive or resistant to cisplatin toxicity. In: Nicolini M (ed) Platinum and other metal cooordination compounds in cancer chemotherapy. Martinus Nijhoff Publishing, Padua, p 207
26. Martin M, Diaz-Rubio E, Casado A, Lopez-Vega JM, Sastre J, Almenarez J (1992) Intravenous and oral magnesium supplementations in the prophylaxis of cisplatin-induced hypomagnesemia. Results of a controlled trial. Am J Clin Oncol 15: 348
27. Miller AA, Hargis JB, Lilienbaum RC, Fields SZ, Rosner GL, Schilsky RL (1994) Phase I study of topotecan and cisplatin in patients with advanced solid tumors: a cancer and leukemia group B study. J Clin Oncol 12: 2743
28. Mistry P, Lee C, McBrien DCH (1989) Intracellular metabolites of cisplatin in the rat kidney. Cancer Chemother Pharmacol 24: 73
29. 2+-calmodulin to the kinetochore of C6 glioma cells: an investigation of the anti-tumor effects of calmodulin antagonists in the treatment of brain tumors. Neurol Res 15: 131
30. Mollman JA (1990) Cisplatin neurotoxicity. New Engl J Med 322: 126
31. Ozols RF, Young RC (1984) Chemotherapy of ovarian cancer. Semin Oncol 11: 251
32. Petrusz P, Merchenthaler I, Weinberg RJ, Grossman G, Ordronneau P (1993) Characterization of an antiserum to citrulline for use in immunocytochemistry. J Histochem Cytochem 41: 1126
33. Richtsmeier WJ, Mazur EM (1986) The use of metaclopromide in treatment of cisplatin-induced emesis. Otolaryngol Head Neck Surg 95: 358
34. Roos IAG, Fairlie D, Whitehouse MW (1981) A peculiar toxicity manifested by platinum (II) amines in rats: gastric distension after intraperitoneal administration. Chem Biol Interact 35: 111
35. Schiller LR (1994) Peristalsis. Sci Am Sci Med 1: 38
36. Sessa WC (1994) The nitric oxide synthase family of proteins. J Vasc Res 31: 131
37. Soediono P, Burnstock G (1994) Contribution of ATP and nitricoxide to NANC inhibitory transmission in rat pyloric sphincter. Br J Pharmacol 113: 681
38. Taudy M, Syka J, Popelar J, Ulehlova L (1992) Carboplatin and cisplatin ototoxicity in guinea pigs. Audiology 31: 293
39. Vander AJ, Sherman JH, Luciano DS (1990) Human physiology: the mechanisms of body function. 5th ed. McGraw-Hill Publishing Co., New York, p 536
40. Zdanski CJ, Prazma J, Petrusz P, Grossman G, Raynor E, Smith TL, Pillsbury HC (1994) Nitric oxide synthase is an active enzyme in the spiral ganglion cells of the rat cochlea. Hear Res 79: 39