Multidomain protein solves the folding problem by multifunnel combined landscape: Theoretical investigation of a Y-family DNA polymerase

Journal of the American Chemical Society

Volumn 134, Issue 33, 2012, Pages 13755-13764

  Wang, Yong ^a   Chu, Xiakun ^b   Suo, Zucai ^c   Wang, Erkang ^a   Wang, Jin ^a,b,d  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b JILIN UNIVERSITY   (China)

^c OHIO STATE UNIVERSITY   (United States)

^d STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FUNCTIONS; CONFORMATIONAL SEARCH; DIVIDE AND CONQUER; DNA POLYMERASE; ENERGY LANDSCAPE; EUKARYOTIC PROTEINS; EXPERIMENTAL DATA; MULTIDOMAIN PROTEINS; MULTIPLE DOMAINS; NATIVE STRUCTURES; ORDERS OF MAGNITUDE; PROTEIN FOLDING PROBLEM; SINGLE-DOMAIN PROTEINS; SULFOLOBUS SOLFATARICUS; THEORETICAL INVESTIGATIONS; THEORETICAL PREDICTION; THEORETICAL RESULT; TIME-SCALES;

DNA; MECHANICS; POLYMERS; PROTEIN FOLDING;

PROTEINS;

DNA POLYMERASE; DNA POLYMERASE IV; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATION; KINETICS; NONHUMAN; PREDICTION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; SULFOLOBUS SOLFATARICUS; THERMODYNAMICS;

DNA POLYMERASE BETA; MODELS, MOLECULAR; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; SULFOLOBUS SOLFATARICUS;

EID: 84865403286     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3045663     Document Type: Article

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