Development of a new chitosan hydrogel for wound dressing

Wound Repair and Regeneration

Volumn 17, Issue 6, 2009, Pages 817-824

  Ribeiro, Maximiano P ^a   Espiga, Ana ^b,c   Silva, Daniela ^a   Baptista, Patrícia ^a   Henriques, Joaquim ^a   Ferreira, Catarina ^a   Silva, Jorge C ^d   Borges, João P ^b   Pires, Eduardo ^b,c   Chaves, Paula ^a   Correia, Ilídio J ^a  

^a UNIVERSITY OF BEIRA INTERIOR   (Portugal)

^b DEPARTAMENTO DE CIÊNCIA DOS MATERIAIS   (Portugal)

^c Campus Do INETI ^*  (Portugal)

^d UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BURN; CELL ADHESION; CELL ISOLATION; CELL PROLIFERATION; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GRANULATION TISSUE; HISTOCOMPATIBILITY; HYDROGEL; NONHUMAN; PRIORITY JOURNAL; PRODUCT DEVELOPMENT; RAT; SCANNING ELECTRON MICROSCOPY; SKIN FIBROBLAST; SKIN INJURY; WOUND DRESSING; WOUND HEALING;

ANIMALS; CELLS, CULTURED; CHITOSAN; FEMALE; FIBROBLASTS; HYDROGELS; RATS; RATS, WISTAR; SKIN; TOXICITY TESTS; WOUND HEALING;

EID: 70350648405     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2009.00538.x     Document Type: Article

References (34)

1. Alemdaroglu C, Degim Z, Celebi N, Zor F, Ozturk S, Erdogan D. An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor. Burns 2006 32 : 319 327.
2. Dai T, Tegos GP, Burkatovskaya M, Castano AP, Hamblin MR. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob Agents Chemother 2009 53 (2 393 400.
3. Kim IY, Seo SJ, Moon HS, Yoo MK, Park IY, Kim BC, Cho CS. Chitosan and its derivatives for tissue engineering applications. Biotechnol Adv 2008 26 : 1 21.
4. Attia J, Legendre F, Nguyen QT, Bauge C, Boumediene K, Pujol JP. Evaluation of adhesion, proliferation, and functional differentiation of dermal fibroblasts on glycosaminoglycan-coated polysulfone membranes. Tissue Eng Part A 2008 14 : 1687 1697.
5. Zeltinger J, Sherwood JK, Graham DA, Mueller R, Griffith LG. Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition. Tissue Eng 2001 7 : 557 572.
6. Chen YM, Shiraishi N, Satokawa H, Kakugo A, Narita T, Gong JP, Osada Y, Yamamoto K, Ando J. Cultivation of endothelial cells on adhesive protein-free synthetic polymer gels. Biomaterials 2005 26 : 4588 4596.
7. Ma L, Gao C, Mao Z, Zhou J, Shen J, Hu X, Han C. Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering. Biomaterials 2003 24 : 4833 4841.
8. Metcalfe AD, Ferguson MW. Bioengineering skin using mechanisms of regeneration and repair. Biomaterials 2007 28 : 5100 5113.
9. Montembault A, Viton C, Domard A. Physico-chemical studies of the gelation of chitosan in a hydroalcoholic medium. Biomaterials 2005 26 : 933 943. (Pubitemid 39194965)
10. Lavertu M, Xia Z, Serreqi AN, Berrada M, Rodrigues A, Wang D, Buschmann MD, Gupta A. A validated 1H NMR method for the determination of the degree of deacetylation of chitosan. J Pharm Biomed Anal 2003 32 : 1149 1158.
11. Montembault A, Viton C, Domard A. Rheometric study of the gelation of chitosan in aqueous solution without cross-linking agent. Biomacromolecules 2005 6 : 653 662.
12. Hong JP, Kim YW, Lee SK, Kim SH, Min KH. The effect of continuous release of recombinant human epidermal growth factor (rh-EGF) in chitosan film on full thickness excisional porcine wounds. Ann Plast Surg 2008 61 : 457 462.
13. Boateng JS, Matthews KH, Stevens HN, Eccleston GM. Wound healing dressings and drug delivery systems: a review. J Pharm Sci 2008 97 : 2892 2923.
14. VandeVord PJ, Matthew HW, DeSilva SP, Mayton L, Wu B, Wooley PH. Evaluation of the biocompatibility of a chitosan scaffold in mice. J Biomed Mater Res 2002 59 : 585 590.
15. Ong SY, Wu J, Moochhala SM, Tan MH, Lu J. Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties. Biomaterials 2008 29 : 4323 4332.
16. Alves NM, Mano JF. Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications. Int J Biol Macromol 2008 43 : 401 414.
17. Ueno H, Yamada H, Tanaka I, Kaba N, Matsuura M, Okumura M, Kadosawa T, Fujinaga T. Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs. Biomaterials 1999 20 : 1407 1414.
18. Mizuno K, Yamamura K, Yano K, Osada T, Saeki S, Takimoto N, Sakurai T, Nimura Y. Effect of chitosan film containing basic fibroblast growth factor on wound healing in genetically diabetic mice. J Biomed Mater Res A 2003 64 : 177 181.
19. Ignatova M, Manolova N, Markova N, Rashkov I. Electrospun non-woven nanofibrous hybrid mats based on chitosan and PLA for wound-dressing applications. Macromol Biosci 2009 9 : 102 111.
20. Blasinska A, Drobnik J. Effects of nonwoven mats of Di-O-butyrylchitin and related polymers on the process of wound healing. Biomacromolecules 2008 9 : 776 782.
21. Azad AK, Sermsintham N, Chandrkrachang S, Stevens WF. Chitosan membrane as a wound-healing dressing: characterization and clinical application. J Biomed Mater Res B Appl Biomater 2004 69 : 216 222.
22. Mi FL, Shyu SS, Wu YB, Lee ST, Shyong JY, Huang RN. Fabrication and characterization of a sponge-like asymmetric chitosan membrane as a wound dressing. Biomaterials 2001 22 : 165 173.
23. Weng L, Romanov A, Rooney J, Chen W. Non-cytotoxic, in situ gelable hydrogels composed of N-carboxyethyl chitosan and oxidized dextran. Biomaterials 2008 29 : 3905 3913.
24. Balakrishnan B, Mohanty M, Umashankar PR, Jayakrishnan A. Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin. Biomaterials 2005 26 : 6335 6342.
25. Garcia Y, Wilkins B, Collighan RJ, Griffin M, Pandit A. Towards development of a dermal rudiment for enhanced wound healing response. Biomaterials 2008 29 : 857 868.
26. Thein-Han WW, Misra RD. Biomimetic chitosan-nanohydroxyapatite composite scaffolds for bone tissue engineering. Acta Biomater 2009 5 : 1182 1197.
27. Montembault A, Viton C, Domard A. Rheometric study of the gelation of chitosan in a hydroalcoholic medium. Biomaterials 2005 26 : 1633 1643. (Pubitemid 39575307)
28. Mori T, Okumura M, Matsuura M, Ueno K, Tokura S, Okamoto Y, Minami S, Fujinaga T. Effects of chitin and its derivatives on the proliferation and cytokine production of fibroblasts in vitro. Biomaterials 1997 18 : 947 951.
29. Hamilton V, Yuan Y, Rigney DA, Puckett AD, Ong JL, Yang Y, Elder SH, Bumgardner JD. Characterization of chitosan films and effects on fibroblast cell attachment and proliferation. J Mater Sci Mater Med 2006 17 : 1373 1381.
30. Liu H, Du Y, Wang X, Sun L. Chitosan kills bacteria through cell membrane damage. Int J Food Microbiol 2004 95 : 147 155.
31. Hong HJ, Jin SE, Park JS, Ahn WS, Kim CK. Accelerated wound healing by smad3 antisense oligonucleotides-impregnated chitosan/alginate polyelectrolyte complex. Biomaterials 2008 29 : 4831 4837.
32. Galiano RD, Michaels J, Dobryansky M, Levine JP, Gurtner GC. Quantitative and reproducible murine model of excisional wound healing. Wound Repair Regen 2004 12 : 485 492.
33. Kiyozumi T, Kanatani Y, Ishihara M, Saitoh D, Shimizu J, Yura H, Suzuki S, Okada Y, Kikuchi M. Medium (DMEM/F12)-containing chitosan hydrogel as adhesive and dressing in autologous skin grafts and accelerator in the healing process. J Biomed Mater Res B Appl Biomater 2006 79 : 129 136.
34. Kimura Y, Sumiyoshi M, Samukawa K, Satake N, Sakanaka M. Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism. Eur J Pharmacol 2008 584 : 415 423.