Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition

Food Chemistry

Volumn 135, Issue 4, 2012, Pages 2378-2386

  Serra, Ana Teresa ^a,b   Rocha, J ^c   Sepodes, B ^c   Matias, Ana A ^a,b   Feliciano, Rodrigo P ^a   De Carvalho, Agostinho ^d   Bronze, Maria R ^a,b,c   Duarte, Catarina M M ^a,b   Figueira, M E ^c  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^c RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^d INSTITUTO SUPERIOR DE CIÊNCIAS DA SAÚDE EGAS MONIZ   (Portugal)

Author keywords

Anti hypercholesterolemic effect; Apples; Bravo de Esmolfe; Cardiovascular disease; Polyphenols

Indexed keywords

ANTI-HYPERCHOLESTEROLEMIC EFFECT; APPLES; BRAVO DE ESMOLFE; CARDIO-VASCULAR DISEASE; POLYPHENOLS;

BODY FLUIDS; CHOLESTEROL; DISEASES; NUTRITION; PHENOLS; PLANTS (BOTANY);

FRUITS;

BETA CAROTENE; BRAVO DE ESMOLFE APPLE EXTRACT; CATECHIN; CHOLESTEROL; EPICATECHIN; GOLDEN APPLE EXTRACT; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALAPIO DA SERRA APPLE EXTRACT; OXIDIZED LOW DENSITY LIPOPROTEIN; PHENOL DERIVATIVE; PLANT EXTRACT; PROCYANIDIN B1; PROCYANIDIN DERIVATIVE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APPLE; ARTICLE; BLOOD SAMPLING; BRAVO DE ESMOLFE APPLE; CARDIOVASCULAR SYSTEM; CHEMICAL COMPOSITION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; CULTIVAR; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG POTENCY; FIBER; GOLDEN APPLE; HEART PROTECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IN VITRO STUDY; IN VIVO STUDY; LIPID ANALYSIS; LIPID BLOOD LEVEL; MALAPIO DA SERRA APPLE; MALE; NONHUMAN; OXIDATIVE STRESS; PORTUGAL; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; CARDIOVASCULAR DISEASES; CHOLESTEROL; DIETARY FIBER; HUMANS; MALE; MALUS; PLANT EXTRACTS; RATS; RATS, WISTAR; TRIGLYCERIDES;

MALUS X DOMESTICA; RATTUS NORVEGICUS;

EID: 84865346819     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.07.067     Document Type: Article

References (47)

1. O. Aprikian, J. Busserolles, C. Manach, A. Mazur, C. Morand, and M. Davicco Lyophilized apple counteracts the development of hypercholesterolemia, oxidative stress, and renal dysfunction in obese Zucker rats Journal of Nutrition 132 2002 1969 1976
2. O. Aprikian, V. Duclos, S. Guyot, C. Besson, C. Manach, and A. Bernalier Apple pectin and a polyphenol rich apple concentrate are more effective together than separately on faecal fermentations and plasma lipids in rats Journal of Nutrition 133 2003 1860 1865
3. O. Aprikian, M. Levrat-Verny, C. Besson, J. Busserolles, C. Remesy, and C. Demigne Apple favourably affects parameters of cholesterol metabolism and of anti-oxidative protection in cholesterol fed rats Food Chemistry 75 2001 445 452
4. L.A. Bazzano, M.K. Serdula, and S. Liu Dietary intake of fruits and vegetables and risk of cardiovascular diseases Current Atherosclerosis Reports 5 2003 429 439
5. J. Boyer, and R.H. Liu Apple phytochemicals and their health benefits Nutrition Journal 3 2006 1 15
6. M.N. Bravo, S. Silva, A.V. Coelho, Boas.L. Vilas, and M.R. Bronze Analysis of phenolic compounds in Muscatel wines produced in Portugal Analytica Chemica Acta 563 2006 84 92
7. P.T. Chan, W.P. Fong, Y.L. Cheung, Y. Huang, W.K.K. Ho, and Z.Y. Chen Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet Journal of Nutrition 129 1999 1094 1101
8. W.H. Chang, and J.F. Liu Effects of kiwifruit consumption on serum lipid profiles and antioxidative status in hyperlipidemic subjects International Journal of Food Sciences and Nutrition 19 2009 11 18
9. S. Coimbra, A. Santos-Silva, P. Rocha-Pereira, S. Rocha, and E. Castro Green tea consumption improves plasma lipid profiles in adults Nutrition Research 26 2006 604 607
10. I. Dauchet, P. Amouyet, and J. Dallongeville Fruit and vegetable consumption and risk of stroke. A meta analysis of cohort studies Neurology 65 2005 1193 1197
11. de Carvalho, A., & Duarte, C. (2009). Maçãs Tradicionais de Eleição- Fonte de Saúde e de Sabores (1st Edition). Agro Manual Publicações Lda (Annex).
12. V. Dewanto, X. Wu, K.K. Adom, and R.H. Liu Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity Journal of Agricultural and Food Chemistry 50 2002 3010 3014
13. N.J. Dubost, B. Ou, and R.B. Beelman Quantification of polyphenols and ergothioneine in cultivated mushrooms and correlation to total antioxidant capacity Food Chemistry 105 2007 727 735
14. M.V. Eberhardt, C.Y. Lee, and R.H. Liu Antioxidant activity of fresh apples Nature 405 2000 903 904
15. M. Egger, G.D. Smith, D. Pfluger, E. Altpeter, and P.C. Elwood Triglyceride as a risk factor for ischaemic heart disease in British men: Effect of adjusting for measurement error Atherosclerosis 143 1999 275 284
16. R.P. Feliciano, C. Antunes, A. Ramos, A.T. Serra, M.E. Figueira, and C.M.M. Duarte Characterization of traditional and exotic apple varieties from Portugal. Part 1 - Nutritional, phytochemical and sensory analysis Journal of Functional Foods 2 2010 35 45
17. R.P. Feliciano, M.N. Bravo, M.M. Pires, A.T. Serra, C. Duarte, and L.V. Boas Phenolic content and antioxidant activity of Moscatel dessert wines from the Setúbal region of Portugal Food Analytical Methods 2 2009 149 161
18. J.M. Gaziano, J.E. Manson, L.G. Branch, G.A. Colditz, W.C. Willett, and J.E. Buring A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly Annals of Epidemiology 5 1995 255 260
19. D. Huang, B. Ou, M. Hampsch-Woodill, J.A. Flanagan, and R.L. Prior High-throughput assay of oxygen radical absorbance capacity (ORAC) using a multichannel liquid handling system coupled with a microplate fluorescence reader in 96-well format Journal of Agricultural and Food Chemistry 50 2002 4437 4444
20. S.I. Koo, and S.K. Noh Green tea as inhibitor of the intestinal absorption of lipids: Potential mechanism for its lipid-lowering effect Journal of Nutritional Biochemistry 18 2007 179 183
21. C.Y. Kwok, C.N. Wong, M.Y.C. Yau, P.H.F. Yu, A.L.S. Au, and C.C.W. Poon Consumption of dried fruit of Crataegus pinnatifida (hawthorn) suppresses high-cholesterol diet-induced hypercholesterolemia in rats Journal of Functional Foods 2 2010 179 186
22. M. Leontowicz, S. Gorinstein, E. Bartnikowska, H. Leontowicz, G. Kulasek, and S. Trakhtenberg Sugar beet pulp and apple pomace dietary fibers improve lipid metabolism in rats fed cholesterol Food Chemistry 72 2001 73 78
23. H. Leontowicz, S. Gorinstein, A. Lojek, M. Leontowicz, M. Ciz, and R. Soliva-Fortuny Comparative content of some bioactive compounds in apples, peaches, and pears and their influence on lipids and antioxidant capacity in rats Journal of Nutritional Biochemistry 1 2002 603 610
24. D.G. Manuel, J. Lim, P. Tanuseputro, G.M. Anderson, D.A. Alter, and A. Laupacis Revisiting Rose: Strategies for reducing coronary heart disease British Medical Journal 332 2006 659 662
25. C. Meisinger, J. Baumert, N. Khuseyinova, H. Loewel, and W. Koening Plasma oxidized low density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population Circulation 112 2005 651 657
26. I. Murakami, T. Nakamura, Y. Ishibashi, R. Shibuya, E. Ayano, and Y. Morita-Murase Simultaneous determination of catechins and procyanidins in bottled tea drinks by LC/MS Chromatography 1 2006 27 33
27. Y. Nagasako-Akazome, T. Kanda, Y. Ohtake, H. Shimasaki, and T. Kobayashi Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index Journal of Oleo Science 56 2007 417 428
28. S. Nagkmonte, K. Makynen, T. Thilawech, and S. Adisakwattana Cholesterol-lowering activity of the major polyphenols in grape seed Molecules 16 2011 5054 5061
29. Y. Negis, N. Aytan, N. Özer, E. Ogru, R. Libinaki, and R. Gianello The effect of cholesterol phosphates on atherosclerosis progression in rabbits fed with a high cholesterol diet Archives of Biochemistry and Biophysics 450 2006 63 66
30. A.R. Ness, and J.W. Powels Fruit and vegetables, and cardiovascular disease: A review International Journal of Epidemiology 26 1997 1 13
31. B. Ou, M. Hampsch-Woodill, J. Flanagan, E.K. Deemer, R.L. Prior, and D. Huang Novel fluorometric assay for hydroxyl radical prevention capacity using fluorescein as the probe Journal of Agricultural and Food Chemistry 50 2002 2772 2777
32. S. Reagan-Shaw, M. Nihal, and N. Ahmad Dose translation from animal to human studies revisited Faseb Journal 22 2008 659 661
33. S.L. Rywik, T.A. Manolio, A. Pajak, W. Piotrowski, C.E. Davis, and G.B. Broda Association of lipids and lipoprotein level with total mortality and mortality caused by cardiovascular and cancer diseases (Poland and United States collaborative study on cardiovascular epidemiology) The American Journal of Cardiology 84 1999 540 548
34. R. Sablé-Amplis, R. Sicart, and R. Agid Further studies on the cholesterol-lowering effect of apple in human Biochemical mechanisms involved. Nutrition Research 3 1983 325 328
35. J.M. Salgado, F. Curte, and D.N. Mansi Effect of gala apples (Malus domestica Borkh) on lipidemia of hyperlipidemic rats Ciência e Tecnologia de Alimentos 28 2008 477 484
36. A.T. Serra, A.A. Matias, R.F.M. Frade, R.O. Duarte, R.P. Feliciano, and M.R. Bronze Characterization of traditional and exotic apple varieties from Portugal. Part 2 - Antioxidant and antiproliferative activities Journal of Functional Food 2 2010 46 53
37. A.T. Serra, A.A. Matias, A.V.M. Nunes, M.C. Leitão, D. Brito, and R. Bronze In vitro evaluation of olive- and grape-based natural extracts as potential preservatives for food Innovative Food Science and Emerging Technologies 9 2008 311 319
38. V.L. Singleton, and J.A. Rossi Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents American Journal of Enology and Viticulture 16 1965 144 158
39. G.D. Smith, M.J. Shipley, M.G. Marmot, and G. Rose Plasma cholesterol concentration and mortality The Whitehall Study. JAMA 267 1992 70 76
40. B.A. Stracke, C.E. Rufer, F.P. Weibel, A. Bub, and B. Watzl Three-year comparison of polyphenol contents and antioxidant capacities in organically and conventionally produced apples (Malus domestica Bork. cultivar "Golden Delicious") Journal of Agricultural and Food chemistry 57 2009 4598 4605
41. K. Sugamura, and J.F. Keaney Reactive oxygen species in cardiovascular disease Free Radical Biology and Medicine 51 2011 978 992
42. D.L. Tribble Antioxidant consumption and risk of coronary heart disease: Emphasis on vitamin C, vitamin E, and beta-carotene: A statement for healthcare professionals from the American Heart Association Circulation 99 1999 591 595
43. P. vańt Veer, M.C. Jansen, M. Klerk, and F.J. Kok Fruits and vegetables in the prevention of cancer and cardiovascular disease Public Health Nutrition 3 2000 103 107
44. U. Vrhovsek, A. Rigo, D. Tonon, and F. Mattivi Quantification of polyphenols in different apple varieties The Journal of Agricultural and Food Chemistry 52 2004 6532 6538
45. H. Wang, and J.A. Joseph Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader Free Radical Biology and Medicine 27 1999 612 616
46. WHO 2011 Report, Global atlas on cardiovascular disease prevention and control.
47. M. Yang, C. Wang, and H. Chen Green, oolong and black tea extracts modulate lipid metabolism in hyperlipidemia rats fed high-sucrose diet The Journal of Nutritional Biochemistry 12 2001 14 20