-
1
-
-
78649307591
-
V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a
-
10.1002/emmm.201000099, 3394506, 20941790
-
Carragher LA, Snell KR, Giblett SM, Aldridge VS, Patel B, Cook SJ, Winton DJ, Marais R, Pritchard CA. V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a. EMBO Mol Med 2010, 2:458-471. 10.1002/emmm.201000099, 3394506, 20941790.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 458-471
-
-
Carragher, L.A.1
Snell, K.R.2
Giblett, S.M.3
Aldridge, V.S.4
Patel, B.5
Cook, S.J.6
Winton, D.J.7
Marais, R.8
Pritchard, C.A.9
-
2
-
-
79960009775
-
Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer
-
10.1038/modpathol.2011.43, 21423154
-
Kriegl L, Neumann J, Vieth M, Greten FR, Reu S, Jung A, Kirchner T. Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer. Mod Pathol 2011, 24:1015-1022. 10.1038/modpathol.2011.43, 21423154.
-
(2011)
Mod Pathol
, vol.24
, pp. 1015-1022
-
-
Kriegl, L.1
Neumann, J.2
Vieth, M.3
Greten, F.R.4
Reu, S.5
Jung, A.6
Kirchner, T.7
-
3
-
-
77951647898
-
Role of the serrated pathway in colorectal cancer pathogenesis
-
10.1053/j.gastro.2009.12.066, 20420948
-
Leggett B, Whitehall V. Role of the serrated pathway in colorectal cancer pathogenesis. Gastroenterology 2010, 138:2088-2100. 10.1053/j.gastro.2009.12.066, 20420948.
-
(2010)
Gastroenterology
, vol.138
, pp. 2088-2100
-
-
Leggett, B.1
Whitehall, V.2
-
4
-
-
78650733422
-
Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review
-
10.1002/ijc.25432, 2958235, 20473920
-
Shima K, Nosho K, Baba Y, Cantor M, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S. Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review. Int J Cancer 2011, 128:1080-1094. 10.1002/ijc.25432, 2958235, 20473920.
-
(2011)
Int J Cancer
, vol.128
, pp. 1080-1094
-
-
Shima, K.1
Nosho, K.2
Baba, Y.3
Cantor, M.4
Meyerhardt, J.A.5
Giovannucci, E.L.6
Fuchs, C.S.7
Ogino, S.8
-
5
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
10.1073/pnas.96.15.8681, 17576, 10411935
-
Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci U S A 1999, 96:8681-8686. 10.1073/pnas.96.15.8681, 17576, 10411935.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
Issa, J.P.6
-
6
-
-
38449113853
-
DNA methylation analysis by pyrosequencing
-
10.1038/nprot.2007.314, 17853883
-
Tost J, Gut IG. DNA methylation analysis by pyrosequencing. Nat Protoc 2007, 2:2265-2275. 10.1038/nprot.2007.314, 17853883.
-
(2007)
Nat Protoc
, vol.2
, pp. 2265-2275
-
-
Tost, J.1
Gut, I.G.2
-
7
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
10.1073/pnas.93.18.9821, 38513, 8790415
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996, 93:9821-9826. 10.1073/pnas.93.18.9821, 38513, 8790415.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
8
-
-
78650352867
-
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa
-
Wallace K, Grau MV, Levine AJ, Shen L, Hamdan R, Chen X, Gui J, Haile RW, Barry EL, Ahnen D, et al. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila) 2010, 3:1552-1564.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1552-1564
-
-
Wallace, K.1
Grau, M.V.2
Levine, A.J.3
Shen, L.4
Hamdan, R.5
Chen, X.6
Gui, J.7
Haile, R.W.8
Barry, E.L.9
Ahnen, D.10
-
9
-
-
79959764747
-
Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing
-
Vasiljevic N, Wu K, Brentnall AR, Kim DC, Thorat MA, Kudahetti SC, Mao X, Xue L, Yu Y, Shaw GL, et al. Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing. Dis Markers 2011, 30:151-161.
-
(2011)
Dis Markers
, vol.30
, pp. 151-161
-
-
Vasiljevic, N.1
Wu, K.2
Brentnall, A.R.3
Kim, D.C.4
Thorat, M.A.5
Kudahetti, S.C.6
Mao, X.7
Xue, L.8
Yu, Y.9
Shaw, G.L.10
-
10
-
-
84857918436
-
A Novel Pit Pattern Identifies the Precursor of Colorectal Cancer Derived From Sessile Serrated Adenoma
-
10.1038/ajg.2011.457, 22233696
-
Kimura T, Yamamoto E, Yamano HO, Suzuki H, Kamimae S, Nojima M, Sawada T, Ashida M, Yoshikawa K, Takagi R, et al. A Novel Pit Pattern Identifies the Precursor of Colorectal Cancer Derived From Sessile Serrated Adenoma. Am J Gastroenterol 2012, 107(3):460-469. 10.1038/ajg.2011.457, 22233696.
-
(2012)
Am J Gastroenterol
, vol.107
, Issue.3
, pp. 460-469
-
-
Kimura, T.1
Yamamoto, E.2
Yamano, H.O.3
Suzuki, H.4
Kamimae, S.5
Nojima, M.6
Sawada, T.7
Ashida, M.8
Yoshikawa, K.9
Takagi, R.10
-
11
-
-
81455125557
-
DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis
-
10.1371/journal.pone.0027889, 3221680, 22132162
-
Konishi K, Watanabe Y, Shen L, Guo Y, Castoro RJ, Kondo K, Chung W, Ahmed S, Jelinek J, Boumber YA, et al. DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One 2011, 6:e27889. 10.1371/journal.pone.0027889, 3221680, 22132162.
-
(2011)
PLoS One
, vol.6
-
-
Konishi, K.1
Watanabe, Y.2
Shen, L.3
Guo, Y.4
Castoro, R.J.5
Kondo, K.6
Chung, W.7
Ahmed, S.8
Jelinek, J.9
Boumber, Y.A.10
-
12
-
-
79960311900
-
Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer
-
10.1158/1078-0432.CCR-10-0763, 21551253
-
Tanaka M, Chang P, Li Y, Li D, Overman M, Maru DM, Sethi S, Phillips J, Bland GL, Abbruzzese JL, Eng C. Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer. Clin Cancer Res 2011, 17:4531-4540. 10.1158/1078-0432.CCR-10-0763, 21551253.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4531-4540
-
-
Tanaka, M.1
Chang, P.2
Li, Y.3
Li, D.4
Overman, M.5
Maru, D.M.6
Sethi, S.7
Phillips, J.8
Bland, G.L.9
Abbruzzese, J.L.10
Eng, C.11
-
13
-
-
79955397102
-
DNA methylation predicts recurrence from resected stage III proximal colon cancer
-
10.1002/cncr.25737, 3117123, 21509761
-
Ahn JB, Chung WB, Maeda O, Shin SJ, Kim HS, Chung HC, Kim NK, Issa JP. DNA methylation predicts recurrence from resected stage III proximal colon cancer. Cancer 2011, 117:1847-1854. 10.1002/cncr.25737, 3117123, 21509761.
-
(2011)
Cancer
, vol.117
, pp. 1847-1854
-
-
Ahn, J.B.1
Chung, W.B.2
Maeda, O.3
Shin, S.J.4
Kim, H.S.5
Chung, H.C.6
Kim, N.K.7
Issa, J.P.8
-
14
-
-
79952362495
-
Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
-
10.1016/j.leukres.2010.10.001, 21035853
-
Zainuddin N, Kanduri M, Berglund M, Lindell M, Amini RM, Roos G, Sundstrom C, Enblad G, Rosenquist R. Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma. Leuk Res 2011, 35:438-443. 10.1016/j.leukres.2010.10.001, 21035853.
-
(2011)
Leuk Res
, vol.35
, pp. 438-443
-
-
Zainuddin, N.1
Kanduri, M.2
Berglund, M.3
Lindell, M.4
Amini, R.M.5
Roos, G.6
Sundstrom, C.7
Enblad, G.8
Rosenquist, R.9
-
15
-
-
79953217628
-
5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer
-
10.1053/j.gastro.2010.12.035, 3073650, 21185836
-
Jover R, Nguyen TP, Perez-Carbonell L, Zapater P, Paya A, Alenda C, Rojas E, Cubiella J, Balaguer F, Morillas JD, et al. 5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer. Gastroenterology 2011, 140:1174-1181. 10.1053/j.gastro.2010.12.035, 3073650, 21185836.
-
(2011)
Gastroenterology
, vol.140
, pp. 1174-1181
-
-
Jover, R.1
Nguyen, T.P.2
Perez-Carbonell, L.3
Zapater, P.4
Paya, A.5
Alenda, C.6
Rojas, E.7
Cubiella, J.8
Balaguer, F.9
Morillas, J.D.10
-
16
-
-
77954954112
-
Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas
-
10.1245/s10434-009-0901-y, 20077021
-
Kim JC, Choi JS, Roh SA, Cho DH, Kim TW, Kim YS. Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas. Ann Surg Oncol 2010, 17:1767-1776. 10.1245/s10434-009-0901-y, 20077021.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 1767-1776
-
-
Kim, J.C.1
Choi, J.S.2
Roh, S.A.3
Cho, D.H.4
Kim, T.W.5
Kim, Y.S.6
-
17
-
-
0032820505
-
Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: association with DNA replication error and shorter survival
-
10.1159/000012023, 10461063
-
Liang JT, Chang KJ, Chen JC, Lee CC, Cheng YM, Hsu HC, Wu MS, Wang SM, Lin JT, Cheng AL. Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: association with DNA replication error and shorter survival. Oncology 1999, 57:149-156. 10.1159/000012023, 10461063.
-
(1999)
Oncology
, vol.57
, pp. 149-156
-
-
Liang, J.T.1
Chang, K.J.2
Chen, J.C.3
Lee, C.C.4
Cheng, Y.M.5
Hsu, H.C.6
Wu, M.S.7
Wang, S.M.8
Lin, J.T.9
Cheng, A.L.10
-
18
-
-
1542472892
-
Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival
-
Maeda K, Kawakami K, Ishida Y, Ishiguro K, Omura K, Watanabe G. Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival. Oncol Rep 2003, 10:935-938.
-
(2003)
Oncol Rep
, vol.10
, pp. 935-938
-
-
Maeda, K.1
Kawakami, K.2
Ishida, Y.3
Ishiguro, K.4
Omura, K.5
Watanabe, G.6
-
19
-
-
74049139131
-
Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivity
-
10.1007/s00432-009-0688-z, 19779933
-
Mitomi H, Fukui N, Tanaka N, Kanazawa H, Saito T, Matsuoka T, Yao T. Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivity. J Cancer Res Clin Oncol 2010, 136:323-331. 10.1007/s00432-009-0688-z, 19779933.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 323-331
-
-
Mitomi, H.1
Fukui, N.2
Tanaka, N.3
Kanazawa, H.4
Saito, T.5
Matsuoka, T.6
Yao, T.7
|