Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100

BMC Biotechnology

Volumn 12, Issue , 2012, Pages

  Maczuga, Piotr ^a,b   Koornneef, Annemart ^a   Borel, Florie ^a,c   Petry, Harald ^a   van Deventer, Sander ^b   Ritsema, Tita ^a   Konstantinova, Pavlina ^a  

^a UNIQURE   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEINS; CMV PROMOTER; MICRORNA (MIRNA); POLYADENYLATION; POLYMERASE II; SHORT HAIRPIN RNA (SHRNA); SMALL INTERFERING RNA (SIRNA); STEM LENGTH; STRUCTURAL CONFIGURATIONS; TRANSCRIPTION START SITE; TRANSCRIPTION TERMINATION;

MOLECULES; POLYMERS; STRUCTURAL OPTIMIZATION; TISSUE; TOXICITY; TRANSCRIPTION;

RNA;

APOLIPOPROTEIN B100; LUCIFERASE; MICRORNA; NUCLEOTIDE; SHORT HAIRPIN RNA; DNA DIRECTED RNA POLYMERASE III; RNA POLYMERASE II; SMALL INTERFERING RNA;

ARTICLE; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RNA INTERFERENCE; ANIMAL; CELL LINE; CELL STRAIN HEK293; COMPARATIVE STUDY; CYTOMEGALOVIRUS; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; PROMOTER REGION; TRANSCRIPTION INITIATION SITE;

ANIMALS; APOLIPOPROTEIN B-100; CELL LINE; CYTOMEGALOVIRUS; HEK293 CELLS; HUMANS; LUCIFERASES; MICRORNAS; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; RNA POLYMERASE II; RNA POLYMERASE III; RNA, SMALL INTERFERING; TRANSCRIPTION INITIATION SITE;

EID: 84865337567     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-12-42     Document Type: Article

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