Gene silencing in androgen-responsive prostate cancer cells from the tissue-specific Prostate-specific antigen promoter

Cancer Research

Volumn 64, Issue 21, 2004, Pages 7661-7663

  Song, Jun ^a   Pang, Shen ^a   Lu, Yingchun ^a   Yokoyama, Kazunari K ^c   Zheng, Jun Ying ^a   Chiu, Robert ^a,b  

^a UCLA SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; PROSTATE SPECIFIC ANTIGEN; RNA POLYMERASE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE SILENCING; GENE THERAPY; HORMONE DEPENDENCE; HORMONE RESPONSE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CARCINOMA; TISSUE SPECIFICITY;

ANDROGENS; BASE SEQUENCE; CELL LINE, TUMOR; GENE SILENCING; HUMANS; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RNA, SMALL INTERFERING;

EID: 7444222459     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-1751     Document Type: Article

References (15)

1. Xia H, Mao Q, Paulson HL, Davidson BL. siRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnol 2002;20:1006-10.
2. Hara M, Kimura H. Two prostate-specific antigens, gamma-seminoprotein and bets-microseminoprotein. J Lab Clin Med 1989;113:541-8.
3. Wang MC, Valenzuela LA, Murphy GP, Chu TM. Purification of a human prostate specific antigen. Investig Urol 1979;17:159-63.
4. Chan DW, Bruzek DJ, Oesterling JE, Rock RC, Walsh PC. Prostate-specific antigen as a marker for prostatic cancer: a monoclonal and polyclonal immunoassay compared. Clin Chem 1987;33:1916-20.
5. Martin DB, Gifford DR, Wright ME, et al. Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium. Cancer Res 2004;64:347-55.
6. Riegman PH, Vlietstra RJ, van der Korput JA, et al. The promoter of the prostate-specific antigen gene contains a functional androgen responsive element. Mol Endocrinol 1991;5:1921-30.
7. Pang S, Taneja S, Dardashti K, et al. Prostate tissue specificity of the prostate-specific antigen promoter isolated from a patient with prostate cancer. Hum Gene Ther 1995;6:1417-26.
8. Louie MC, Yang HQ, Ma AH, et al. Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex. Proc Natl Acad Sci USA 2003;100:2226-30.
9. Pang S, Dannull J, Kaboo R, et al. Identification of a positive regulatory element responsible for tissue-specific expression of prostate-specific antigen. Cancer Res 1997;57:495-9.
10. Yu D, Chen D, Chiu C, et al. Prostate-specific targeting using PSA promoter based lentiviral vectors. Cancer Gene Ther 2001;8:628-35.
11. Rubinson DA, Dillon CP, Kwiatkowski AV, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003;33:401-6.
12. Lois C, Hong EJ, Pease S, et al. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science (Wash DC) 2002;295:868-72.
13. Tiscornia G, Singer O, Ikawa M, et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA 2003;100:1844-8.
14. Song J, Lu YC, Yokoyama K, et al. Cyclophilin A is required for retinoic acid-induced neuronal differentiation of p19 cells. J Biol Chem 2004;279:24414-9.
15. Beresford SA, Davies MA, Gallick GE, et al. Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptosis sensitization to cytokines in LNCaP and PC-3 prostate cancer cells. Interferon Cytokine Res 2001;21:313-22.