Discovering Bisdemethoxycurcumin from Curcuma longa rhizome as a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes

Food Chemistry

Volumn 135, Issue 4, 2012, Pages 2638-2642

  Ponnusamy, Sudha ^a   Zinjarde, Smita ^a   Bhargava, Shobha ^a   Rajamohanan, P R ^b   Ravikumar, Ameeta ^a  

^a UNIVERSITY OF PUNE   (India)

^b NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

BDMC; Curcuma longa; Human pancreatic amylase; Kinetics; Type 2 diabetes

Indexed keywords

ANTI-INFLAMMATORIES; APPARENT K; BDMC; BISDEMETHOXYCURCUMIN; CURCUMA LONGA; CURCUMINOIDS; DRUG CANDIDATES; FUNCTIONAL FOODS; HEALTH BENEFITS; ISO-PROPANOLS; KINETIC ANALYSIS; SMALL MOLECULE INHIBITOR; SOUTHEAST ASIA; THERAPEUTIC TARGETS; TYPE-2 DIABETES;

ENZYME KINETICS; MOLECULES; STARCH;

AMYLASES;

ALPHA AMYLASE PANCREAS ISOENZYME; ALPHA GLUCOSIDASE; AMYLASE INHIBITOR; ANTIDIABETIC AGENT; DIDEMETHOXYCURCUMIN; PLANT EXTRACT;

ANTIDIABETIC ACTIVITY; ARTICLE; CURCUMA LONGA; DRUG ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KINETICS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE;

CURCUMA; CURCUMIN; DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; HUMANS; KINETICS; MOLECULAR WEIGHT; PANCREATIC ALPHA-AMYLASES; PLANT EXTRACTS; RHIZOME;

CURCUMA LONGA; SUS;

EID: 84865311005     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.06.110     Document Type: Article

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