Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants

BMC Complementary and Alternative Medicine

Volumn 11, Issue , 2011, Pages

  P, Sudha ^a   Zinjarde, Smita S ^a   Bhargava, Shobha Y ^a   Kumar, Ameeta R ^a  

^a UNIVERSITY OF PUNE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DINITROSALICYLIC ACID; ACARBOSE; ADANSONIA DIGITATA EXTRACT; ALKALOID; ALOE VERA EXTRACT; ALPHA AMYLASE PANCREAS ISOENZYME; AMYLASE; BLACK PEPPER EXTRACT; CASIA FISTULA EXTRACT; CATHARANTHUS ROSEUS EXTRACT; CINNAMOMUM VERUM EXTRACT; COCCINIA GRANDIS EXTRACT; GARLIC EXTRACT; GINGER EXTRACT; IODINE; LINUM USITATISUMUM EXTRACT; MANGIFERA INDICA EXTRACT; MULBERRY EXTRACT; NERIUM OLEANDER EXTRACT; OCIMUM TENUIFLORUM EXTRACT; PLANT EXTRACT; PORCINE PANCREATIC ALPHA AMYLASE; SALICYLIC ACID DERIVATIVE; SOLVENT; STARCH; TANNIN DERIVATIVE; TERMINALIA CHEBULA EXTRACT; TINOSPORA CORDIFOLIA EXTRACT; TRIGONELLA FOENUM GRAECUM EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ADANSONIA; ALOE VERA; ARTICLE; AYURVEDA; BASIL; BIOASSAY; BLACK PEPPER; CASIA FISTULA; CATHARANTHUS ROSEUS; CINNAMOMUM; CINNAMOMUM VERUM; COCCINIA GRANDIS; DRUG DETERMINATION; DRUG INHIBITION; ENZYME INHIBITION; EXTRACTION; FENUGREEK; GARLIC; GINGER; IC 50; INDIAN; INVERSE GAS CHROMATOGRAPHY; LINUM USITATISUMUM; MANGO; MEDICINAL PLANT; MINIMUM INHIBITORY CONCENTRATION; MULBERRY; NERIUM; NONHUMAN; OCIMUM TENUIFLORUM; PHYTOCHEMISTRY; PLANT LEAF; QUALITATIVE ANALYSIS; TERMINALIA CHEBULA; TINOSPORA; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; FLAX; INDIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYTOTHERAPY; SWINE;

ACARBOSE; ALPHA-AMYLASES; ANIMALS; DIABETES MELLITUS, TYPE 2; FLAX; INDIA; INHIBITORY CONCENTRATION 50; MEDICINE, AYURVEDIC; MORUS; OCIMUM; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; SWINE;

EID: 79851492687     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-11-5     Document Type: Article

References (52)

1. World Health Organisation Consultation Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Report of a WHO Consultation 1999, Geneva, World Health Organisation Consultation.
2. Gupta OP, Phatak S. Pandemic Trends in Prevalence of Diabetes Mellitus and Associated Coronary Heart Disease in India - Their Causes and Prevention. Int J Diabetes Dev Countries 2003, 23:37-50.
3. Leena AA, Jill PC. Type 2 Diabetes Prevention: A Review. Clinical Diabetes 2010, 28(2):53-59.
4. Rang HP, Dale MM, Ritter JM, Moore PK. Pharmacology 2003, 382. Churchill Livingstone, 5.
5. Eichler HG, Korn A, Gasic S, Prison W, Businger J. The effect of new specific α-amylase inhibitor on post-prandial glucose and insulin excursions in normal subjects and Type 2 (non-insulin dependent) diabetic patients. Diabetologia 1984, 26(4):278-281. 10.1007/BF00283650, 6376235.
6. Tarling CA, Woods K, Zhang R, Brastianos HC, Brayer GD, Andersen RJ, Withers SG. The Search for Novel Human Pancreatic α-Amylase Inhibitors: High-Throughput Screening of Terrestrial and Marine Natural Product Extracts. ChemBioChem 2008, 9:433-438. 10.1002/cbic.200700470, 18214874.
7. Cheng AYY, Fantus IG. Oral antihyperglycemic therapy for type 2 diabetes mellitus. Canadian Medicinal Association Journal 2005, 172(2):213-226.
8. Grover JK, Yadav S, Vats V. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol 2002, 81:81-100. 10.1016/S0378-8741(02)00059-4, 12020931.
9. Mukherjee PK, Maiti K, Mukherjee K, Houghton PJ. Leads from Indian medicinal plants with hypoglycemic potentials. J Ethnopharmacol 2006, 106(1):1-28. 10.1016/j.jep.2006.03.021, 16678368.
10. Babu PA, Suneetha G, Boddepalli R, Lakshmi VV, Rani TS, Rambabu Y, Srinivas K. A database of 389 medicinal plants for diabetes. Bioinformation 2006, 1(4):130-171. 1891668, 17597872.
11. Farnsworth NR. Screening plants for new medicines 1998, 83-97. Biodiversity National Academy Press, Washington DC, Wilson EO.
12. Elder C. Ayurveda for diabetes mellitus: a review of the biomedical literature. Altern Ther Health Med 2004, 10(1):44-50.
13. Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants 1986, Council of Scientific and Industrial Research, ND. India.
14. WHO Footnote to Annex 3. WHO Expert Committee on Diabetes Mellitus, 2nd Report. Technical Report Series #646 1980, 9. WHO, WHO.
15. Creutzfeldt W. Effects of the α-glucosidase Inhibitor Acarbose on the Development of Long-term Complications in Diabetic Animals: Pathophysiological and Therapeutic Implications. Diabetes Metab Res Rev 1999, 15:289-296. 10.1002/(SICI)1520-7560(199907/08)15:4<289::AID-DMRR48>3.0.CO;2-V, 10495478.
16. Mertes G. Safety and efficacy of acarbose in the treatment of Type 2 diabetes: data from a 5-year surveillance study. Diabetes Research and Clinical Practice 2001, 52:193-204. 10.1016/S0168-8227(01)00221-2, 11323089.
17. Gupta R, Bajpai KG, Johri S, Saxena AM. An overview of Indian Novel traditional medicinal plants with antidiabetic potentials. Afr J Trad CAM 2008, 5(1):1-17.
18. Tanko Y, Yerima M, Mahdi MA, Yaro AH, Mohammed A. Hypoglycemic Activity of Methanolic Stem Bark of Adansonnia digitata Extract on Blood Glucose Levels of Streptozocin-Induced Diabetic Wistar Rats. International Journal of Applied Research in Natural Products 2008, 1(2):32-36.
19. Rizvi MMA, Irshad M, Gamal El Hassadi G, Younis SB. Bioefficacies of Cassia fistula: An Indian labrum. African Journal of Pharmacy and Pharmacology 2009, 3(6):287-292.
20. Thakur G, Mitra A, Pal K, Rousseau D. Effect of flaxseed gum on reduction of blood glucose & cholesterol in Type 2 diabetic patients. Int J Food Sci Nutr 2009, 60(S6):126-136.
21. Ishikawa A, Yamashita H, Hiemori M, Inagaki E, Kimoto M, Okamoto M, Tsuji H, Memon AN, Mohammadi A, Natori Y. Characterization of inhibitors of post prandial hyperglycemia from the leaves of Nerium indicum. Journal of Nutritional Science and Vitaminology 2007, 53:16-173.
22. Brayer GD, Luo Y, Withers SG. The structure of human pancreatic α-amylase at 1.8 A resolution and comparisons with related enzymes. Protein Science 1995, 4:1730-1742. 10.1002/pro.5560040908, 2143216, 8528071.
23. Xiao Z, Storms R, Tsang A. A quantitative starch-iodine method for measuring alpha-amylase and glucoamylase activities. Anal Biochem 2006, 351(1):146-148. 10.1016/j.ab.2006.01.036, 16500607.
24. Miller GL. Use of dinitrosalicylic acid reagent for determination of reducing sugar. Analytical chemistry 1959, 31:426-428.
25. Parekh J, Chanda SV. In vitro Antimicrobial Activity and Phytochemical Analysis of Some Indian Medicinal Plants. Turk J Biol 2007, 31:53-58.
26. Trease GE, Evans WC. Pharmacognsy 1989, Brailliar Tiridel Can. Macmillian publishers, 11.
27. Layer P, Rizza RA, Zinsmeister AR, Carlson GL, DiMagno EP. Effect of a purified amylase inhibitor on carbohydrate tolerance in normal subjects and patients with diabetes mellitus. Mayo Clin Proc 1986, 61(6):442-447.
28. Tundis R, Loizzo MR, Menichini F. Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update. Mini Rev Med Chem 2010, 10(4):315-331. 10.2174/138955710791331007, 20470247.
29. Mangold HK, Spener F. The cyclopentenyl fatty acids. 'Lipids and Lipid Polymers in Higher Plants' 1977, 85-101. Springer-Verlag, Berlin, Tevini M, Lichtenthaler HK.
30. Sebedio JL, Grandgirard A. Cyclic fatty acids: natural sources, formation during heat treatment, synthesis and biological properties. Progr Lipid Res 1989, 28:303-336.
31. Stasevich OV, Mikhalenok SG, Kurchenko VP. Isolation of secoisolariciresinol diglucoside from lignan containing extract of Linum usitatisumum seeds. Chem of Nat Compounds 2009, 45(1):21-23.
32. Bhat M, Zinjarde SS, Bhargava SY, Ravikumar A, Joshi BN. Antidiabetic Indian Plants: A Good Source of Potent Amylase Inhibitors. Evid Based Complement Altern Med 2008,
33. Arpornsuwan T, Wetprasit N, Promboon A, Ratanapo S. Antibacterial activity and cytotoxicity of the leaf essential oil of Morus rotunbiloba Koidz. J Med Plant Res 2010, 4(9):837-843.
34. Song W, Wang HJ, Zhang PF, Wei DZ, Lu Y. Phytochemical Profiles of Different Mulberry (Morus sp.) Species from China. J Agric Food Chem 2009, 57(19):9133-9140. 10.1021/jf9022228, 19761189.
35. Vani SR, Cheng SF, Chuah CH. Comparative Study of Volatile Compounds from Genus Ocimum. Am J Appl Sci 2009, 6(3):523-528.
36. Charles DJ, Simon JE, Wood KV. Essential Oil Constituents of Ocimum micranthum Willd. J Agric Food Chem 1990, 30(1):120-122.
37. Vaccarello-Dunkel F, Weaver DK, Weaver TW. Insecticidal or insect behaviourally active preparations from aromatic plants. United States Patent, 5,591,435 1997,
38. Chattopadhyay RR. Hypoglycemic effect of Ocimum sanctum leaf extract in normal and streptozotocin diabetic rats. Indian J Exp Biol 1993, 31:891-893.
39. Loizzo MR, Saab AM, Statti GA, Menichini F. Composition and α-amylase inhibitory effect of essential oils from Cedrus libani. Fitoterapia 2007, 78(4):323-326. 10.1016/j.fitote.2007.03.006, 17499940.
40. Eidia A, Eidib M, Esmaeillia E. Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine 2006, 13:624-629. 10.1016/j.phymed.2005.09.010, 17085291.
41. Yagi A, Hegazy S, Kabbash A, Abd-El Wahab E. Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on Type 2 Diabetic patients. Saudi Pharmaceutical Journal 2009, 17(3):210-218.
42. Nammi S, Boini MK, Lodagala S, Behara RBS. The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits. BMC Compl Alternative Med 2003, 3(4):1-4.
43. Verspohl EJ, Bauer K, Neddermann E. Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicumin vivo and in vitro. Phytother Res 2005, 19(3):203-206. 10.1002/ptr.1643, 15934022.
44. Shibib BA, Khan LA, Rahman R. Hypoglycaemic activity of Coccinia indica and Momordica charantia indiabetic rats: depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase. Biochem J 1993, 292:267-270. 1134299, 8389127.
45. Bhowmik A, Khan LA, Akhter M, Rokeya B. Studies on the antidiabetic effects of Mangifera indica stem-barks and leaves on nondiabetic, type 1 and type 2 diabetic model rats. Bangladesh J Pharmacol 2009, 4:110-114.
46. Mohammadi J, Naik PR. Evaluation of Hypoglycemic effect of Morus alba in an animal model. Indian J of Pharmacoly 2008, 40(1):15-18.
47. Sethi J, Sood S, Seth S Talwar A. Evaluation of Hypoglycemic and Antioxidant Effect of Ocimum sanctum. Indian J Clin Biochem 2004, 19(2):152-155.
48. Kaleem M, Sarmad H, Bano B. Protective Effects of Piper nigrum and Vinca rosea in Alloxan induced Diabetic Rats. Indian J Physiol Pharmacol 2005, 49(1):65-71.
49. Rao NK, Nammi S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC Compl Alternative Med 2006, 6(17):1-6.
50. Singh SS, Pandey SC, Srivastava S, Gupta VS, Patro B, Ghosh AC. Chemistry and Medicinal Properties of Tinospora cordifolia (Guduchi). Indian J of Pharmacol 2003, 3:83-91.
51. Ismail MYM. Clinical Evaluation of Antidiabetic Activity of Trigonella Seeds and Aegle marmelos Leaves. World Applied Sciences Journal 2009, 7(10):1231-1234.
52. Agoreyo FO, Agoreyo BO, Onuorah MN. Effect of aqueous extracts of Hibiscus sabdariffa and Zingiber Officinale on blood cholesterol and glucose levels of rats. Phytother Res 2006, 20:764-772. 10.1002/ptr.1952, 16807883.