Pyrroloquinoline quinone stimulates epithelial cell proliferation by activating epidermal growth factor receptor through redox cycling

Free Radical Biology and Medicine

Volumn 53, Issue 6, 2012, Pages 1239-1251

  Kimura, Kazuki ^a   Takada, Mayumi ^a   Ishii, Takeshi ^b   Tsuji Naito, Kentaro ^c   Akagawa, Mitsugu ^a  

^a Osaka Prefecture University   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c DHC Corporation   (Japan)

Author keywords

Cell proliferation; Epidermal growth factor; Protein tyrosine phosphatase; Pyrroloquinoline quinone; Receptor tyrosine kinase; ROS

Indexed keywords

ANTIOXIDANT; CYSTEINE; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROGEN PEROXIDE; PROTEIN TYROSINE PHOSPHATASE 1B; PYRROLOQUINOLINEQUINONE; REACTIVE OXYGEN METABOLITE;

ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; OXIDATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G1 PHASE CELL CYCLE CHECKPOINTS; GROWTH SUBSTANCES; HUMANS; MAP KINASE SIGNALING SYSTEM; OXIDATION-REDUCTION; PHOSPHORYLATION; PQQ COFACTOR; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; UP-REGULATION;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 84865288567     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.015     Document Type: Article

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