Quaternized chitosan-coated nanofibrous materials containing gossypol: Preparation by electrospinning, characterization and antiproliferative activity towards HeLa cells

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 10-24

  Ignatova, Milena ^a   Manolova, Nevena ^a   Toshkova, Reneta ^b   Rashkov, Iliya ^a   Gardeva, Elena ^b   Yossifova, Liliya ^b   Alexandrov, Marin ^b  

^a INSTITUTE OF POLYMERS   (Bulgaria)

^b BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

Author keywords

Antitumor activity; Apoptosis; Electrospinning; Gossypol; Polylactide; Quaternized chitosan

Indexed keywords

CHITOSAN DERIVATIVE; GOSSYPOL; KETOCONAZOLE; NANOFIBER; NANOMATERIAL; POLYLACTIDE; QUATERNIZED CHITOSAN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DIFFUSION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; ELECTROSPINNING; FEMALE; FILM; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NANOTECHNOLOGY; PRIORITY JOURNAL; TUMOR CELL;

APOPTOSIS; CELL PROLIFERATION; CHITOSAN; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; GOSSYPOL; HELA CELLS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NANOFIBERS; POLYESTERS; POLYETHYLENE GLYCOLS;

EID: 84865281497     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.035     Document Type: Article

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