Electrospun nanofibrous mats containing quaternized chitosan and polylactide with in vitro antitumor activity against hela cells

Biomacromolecules

Volumn 11, Issue 6, 2010, Pages 1633-1645

  Ignatova, Milena G ^a   Manolova, Nevena E ^a   Toshkova, Reneta A ^b   Rashkov, Iliya B ^a   Gardeva, Elena G ^b   Yossifova, Lilia S ^b   Alexandrov, Marin T ^b  

^a INSTITUTE OF POLYMERS   (Bulgaria)

^b BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CHITIN; CHITOSAN; X RAY PHOTOELECTRON SPECTROSCOPY;

ANTI-TUMOR EFFICACY; ANTITUMOR DRUGS; ANTITUMOR EFFECT; APOPTOSIS; ATR FTIR; CELL VIABILITY; D , L-LACTIDE; DOXORUBICIN HYDROCHLORIDE; ELECTROSPUNS; HELA CELL; IN-VITRO; L-LACTIDE; MICROSCOPIC OBSERVATIONS; ONE-STEP METHODS; POLY LACTIDE; RELEASE PROCESS; RELEASE RATE; SEM; TEM;

CONTROLLED DRUG DELIVERY;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; CHITOSAN DERIVATIVE; DOXORUBICIN; NANOMATERIAL; POLYLACTIDE; PRISTINE; QUATERNIZED CHITOSAN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; CHITOSAN; DRUG CARRIER; N-TRIMETHYL CHITOSAN CHLORIDE; NANOFIBER; POLYESTER;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DIFFUSION COEFFICIENT; DRUG RELEASE; ELECTROSPINNING; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; X RAY PHOTOELECTRON SPECTROSCOPY; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ELECTROCHEMICAL ANALYSIS; HELA CELL LINE; SURFACE PROPERTY;

ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; CHITOSAN; DOXORUBICIN; DRUG CARRIERS; ELECTROCHEMICAL TECHNIQUES; HELA CELLS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; NANOFIBERS; PHOTOELECTRON SPECTROSCOPY; POLYESTERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES;

EID: 77954591331     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm100285n     Document Type: Article

References (48)

1. Crown, J.; Dieras, V.; Kaufmann, M.; von Minckwitz, G.; Kaye, S.; Leonard, R.; Marty, M.; Misset, J.-L.; Osterwalder, B.; Piccart, M. Lancet Oncol. 2002, 3, 719-727.
2. Freedman, R. S.; Herson, J.; Wharton, J. T.; Rutledge, F. N. Cancer Clin. Trials 1980, 3, 345-350.
3. Malkasian, G. D.; Decker, D. G.; Green, S. J.; Edmonson, J. H.; Jefferies, J. A.; Webb, M. J. Gynecol. Oncol. 1981, 11, 235-239.
4. Xiangyang, X.; Ling, L.; Jianping, Z.; Shiyue, L.; Jie, Y.; Xiaojin, Y.; Jinsheng, R. Colloids Surf., B 2007, 55, 222-228.
5. Janes, K. A.; Fresneau, M. P.; Marazuela, A.; Fabra, A.; Alonso, M. J. J. Controlled Release 2001, 73, 255-267.
6. Hu, F.-Q.; Liu, L.-N.; Du, Y.-Z.; Yuan, H. Biomaterials 2009, 30, 6955-6963.
7. Ignatova, M.; Manolova, N.; Markova, N.; Rashkov, I. Macromol. Biosci. 2009, 9, 102-111.
8. Paneva, D.; Ignatova, M.; Manolova, N.; Rashkov, I. Chapter 3. In Nanofibers: Fabrication, Performance, and Applications; Chang, W. N., Ed.; Nova Science Publishers.: New York, 2009; pp 73-151.
9. Xu, X.; Yang, L.; Xu, X.; Wang, X.; Chen, X.; Liang, Q.; Zeng, J.; Jing, X. J. Controlled Release 2005, 108, 33-42.
10. Xu, X.; Chen, X.; Xu, X.; Lu, T.; Wang, X.; Yang, L.; Jing, X. J. Controlled Release 2006, 114, 307-316.
11. Xu, X. L.; Chen, X. S.; Wang, Z.; Jing, X. B. Eur. J. Pharm. Biopharm. 2009, 72, 18-25.
12. Ranganath, S. H.; Wang, C.-H. Biomaterials 2008, 29, 2996-3003.
13. Zeng, J.; Xu, X.; Chen, X.; Liang, Q.; Bian, X.; Yang, L.; Jing, X. J. Controlled Release 2003, 92, 227-231.
14. Xu, X.; Chen, X.; Mab, P.; Wang, X.; Jing, X. Eur. J. Pharm. Biopharm. 2008, 70, 165-170.
15. Han, H. D.; Song, C. K.; Park, Y. S.; Noh, K. H.; Kim, J. H.; Hwang, T.; Kim, T. W.; Shin, B. C. Int. J. Pharm. 2008, 350, 27-34.
16. Park, J. H.; Saravanakumar, G.; Kim, K.; Kwon, I. C. Adv. Drug Delivery Rev. 2010, 62, 28-41.
17. Qin, C.; Du, Y.; Xiao, L.; Li, Z.; Gao, X. Int. J. Biol. Macromol. 2002, 31, 111-117.
18. Kim, C. H.; Choi, J. W.; Chun, H. J.; Choi, K. S. Polym. Bull. 1997, 38, 387-393.
19. Kim, J. Y.; Lee, J. K.; Lee, T. S.; Park, W. H. Int. J. Biol. Macromol. 2003, 32, 23-27.
20. Huang, R.; Mendis, E.; Rajapakse, N.; Kim, S.-K. Life Sci. 2006, 78, 2399-2408.
21. Ignatova, M.; Starbova, K.; Markova, N.; Manolova, N.; Rashkov, I. Carbohydr. Res. 2006, 341, 2098-2107.
22. Ignatova, M.; Manolova, N.; Rashkov, I. Eur. Polym. J. 2007, 43, 1112-1122.
23. Spasova, M.; Mincheva, R.; Paneva, D.; Manolova, N.; Rashkov, I. J. Bioact. Compat. Polym. 2006, 21, 465-479.
24. Rasband, W. S. Image J; U.S. National Institute of Health: Bethesda, MD; 1997-2006. http://rsb.info.nih.gov/ij/
25. Mossmann, T. J. Immunol. Methods 1983, 65, 55-63
26. Wahab, S. I. A.; Abdul, A. B.; Alzubairi, A. S.; Elhassan, M. M.; Mohan, S. J. Biomed. Biotechnol. 2009, 2009, 769568.
27. Zeng, J.; Hou, H.; Schaper, A.; Wendorff, J.; Greiner, A. e-Polym. 2003, 009.
28. Spasova, M.; Manolova, N.; Paneva, D.; Rashkov, I. e-Polym. 2004, 056.
29. Mincheva, R.; Paneva, D.; Manolova, N.; Rashkov, I. J. Bioact. Compat. Polym. 2005, 20, 419-435.
30. Kim, C. H.; Khil, M. S.; Kim, H. Y.; Lee, H. U.; Jahng, K. Y. J. Biomed. Mater. Res. 2006, 78B, 283-290.
31. Cui, W.; Li, X.; Zhou, S.; Weng, J. Polym. Degrad. Stab. 2008, 93, 731-738.
32. Cui, W.; Zhu, X.; Yang, Y.; Li, X.; Jin, Y. Mater. Sci. Eng., C 2009, 29, 1869-1876.
33. Ma, M.; Hill, R. M.; Lowery, J.L.; Fridrikh, S. V.; Rutledge, G. C. Langmuir 2005, 21, 5549-5554.
34. Wang, J. X.; Wang, Z. H.; Chen, J. F.; Yun, J. Mater. Res. Bull. 2008, 43, 3374-3381.
35. Han, J.; Chen, T.-X.; Branford-White, C. J.; Zhu, L.-M. Int. J. Pharm. 2009, 382, 215-221.
36. Doonan, F.; Cotter, T. G. Methods 2008, 44, 200-204
37. Majumdar, S. K.; Valdellon, J. A.; Brown, K. A. J. Biomed. Biotechnol. 2001, 1, 99-107
38. Lee, J. K.; Lim, H. S.; Kim, J. H. Bioorg. Med. Chem. Lett. 2002, 12, 2949-2951.
39. Barry, M. A.; Behnke, C. A.; Eastmann, A. Biochem. Pharmacol. 1990, 40, 2353-2362
40. Hickman, J. A. Cancer Metastasis Rev. 1992, 11, 121-139.
41. Sen, S.; D'Incalci, M. FEBS Lett. 1992, 307, 122-127.
42. Schulte-Hermann, R.; Kraupp Grasle, B.; Bursch, W. Mutat. Res. 2000, 464, 13-18.
43. Pae, H. O.; Seo, W. G.; Kim, N. Y.; Oh, G. S.; Kim, G. E.; Kim, Y. H.; Kwak, H. J.; Yun, Y. G.; Jun, C. D.; Chung, H. T. Leukemia Res. 2001, 25, 339-346.
44. Xu, Q.; Dou, J.; Wei, P.; Tan, C.; Yun, X.; Wu, Y.; Bai, X.; Ma, X.; Du, Y. Carbohydr. Polym. 2008, 71, 509-514.
45. Lin, S. Y.; Chan, H. Y.; Shen, F. H.; Chen, M. H.; Wang, Y. J.; Yu, C. K. J. Cell Biochem. 2007, 100, 1573-1580.
46. Barry, M. A.; Behnke, C. A.; Eastmann, A. Biochem. Pharmacol. 1990, 40, 2353-2362.
47. Fantin, V. R; Berardi, M. J.; Scorrano, L.; Korsmeyer, S. J.; Leder, P. Cancer Cell 2002, 2, 29-42.
48. Monsonégo, J. Gynecol. Obstet. Fertil. 2006, 34, 189-201.