Genipin-crosslinked silk fibroin/hydroxybutyl chitosan nanofibrous scaffolds for tissue-engineering application

Journal of Biomedical Materials Research - Part A

Volumn 95, Issue 3 A, 2010, Pages 870-881

  Zhang, Kuihua ^a,b   Qian, Yongfang ^a   Wang, Hongsheng ^a   Fan, Linpeng ^a   Huang, Chen ^a   Yin, Anlin ^a   Mo, Xiumei ^a  

^a DONGHUA UNIVERSITY   (China)

^b JIAXING UNIVERSITY   (China)

Author keywords

Crosslink; Electrospinning; Genipin; Tissue engineering

Indexed keywords

CELL VIABILITY; CROSS LINKING AGENTS; CROSSLINKED; CROSSLINKS; ELECTROSPUN NANOFIBERS; FT-IR-ATR; GENIPIN; GLUTARALDEHYDES; IN-VITRO; MEAN DIAMETER; NANOFIBROUS SCAFFOLDS; RANDOM COIL; SEM; SILK FIBROIN; TISSUE ENGINEERING SCAFFOLD; WOUND DRESSINGS; WOUND HEALING;

ALDEHYDES; BIOCOMPATIBILITY; BIOMECHANICS; CHITIN; CHITOSAN; ELECTROSPINNING; ENGINEERING; ETHANOL; MECHANICAL PROPERTIES; NANOFIBERS; PORE STRUCTURE; SCAFFOLDS; SILK; WATER VAPOR;

TISSUE ENGINEERING;

ALCOHOL; CHITOSAN DERIVATIVE; GENIPIN; GLUTARALDEHYDE; HYDROXYBUTYL CHITOSAN; SILK FIBROIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA SHEET; BIOCOMPATIBILITY; CELL VIABILITY; CYTOTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; POROSITY; PROTEIN CROSS LINKING; RAT; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; WOUND DRESSING; WOUND HEALING;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; CHITOSAN; CHOLAGOGUES AND CHOLERETICS; CROSS-LINKING REAGENTS; ENDOTHELIAL CELLS; FIBROINS; IRIDOID GLYCOSIDES; MATERIALS TESTING; MOLECULAR STRUCTURE; NANOFIBERS; POROSITY; PROTEIN CONFORMATION; RATS; SWINE; TENSILE STRENGTH; TISSUE ENGINEERING; TISSUE SCAFFOLDS; WOUND HEALING;

EID: 78249285248     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32895     Document Type: Article

References (34)

1. Xu CY, Inai R, Kotaki M, Ramakrishna S,. Aligned biodegradable nanofibrous structure: A potential scaffold for blood vessel engineering. Biomaterials 2004; 25: 877 -886.
2. Min BM, Lee G, Kim SH, Nam YS, Lee TS, Park WH,. Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro. Biomaterials 2004; 25: 1289 -1297.
3. Wang M, Jin HJ, David L, Rutledge GC,. Mechanical properties of electrospun silk fibers. Macromolecules 2004; 37: 6856 -6864.
4. Li WJ, Laurencin CT, Caterson EJ, Tuan RS, Ko FK,. Electrospun nanofibrous structure: A novel scaffold for tissue engineering. J Biomed Mater Res 2002; 60: 613 -621.
5. Dang JM, Leong KW,. Myogenic induction of aligned mesenchymal stem cell sheets by culture on thermally responsive electrospun nanofibers. Adv Mater 2007; 19: 2775 -2779.
6. Chen BY, Dang JY, Tan TL, Fang N, Chen WN, Leong KW, Chan V,. Dynamics of smooth muscle cell deadhesion from thermosensitivehydroxybutyl chitosan. Biomaterials 2007; 28: 1503 -1514.
7. Dang JM, Sun DDN, Shin Y, Sieber AN, Kostuik JP, Leong KW,. Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells. Biomaterials 2006; 27: 406 -418.
8. Jeong L, Lee KY, Liu JW, Park WH,. Time-resolved structural investigation of regenerated silk fibroin nanofibers treated with solvent vapor. Int J Biol Macromol 2006; 38: 140 -144.
9. Min BM, Jeong L, Lee KY, Park WH,. Regenerated silk fibroin nanofibers: Water vapor-induced structural changes and their effects on the behavior of normal human cells. Macromol Biosci 2006; 6: 285 -292.
10. Schiffman JD, Schauer CL,. Cross-linking chitosan nanofibers. Biomacromolecules 2007; 8: 594 -601.
11. Zhou YS, Yang DZ, Chen XM, Xu Q, Lu FM, Nie J,. Electrospun water-soluble carboxyethyl chitosan/poly(vinyl alcohol) nanofibrous membrane as potential wound dressing for skin regeneration. Biomacromolecules 2008; 9: 349 -354.
12. Chiono V, Pulieri E, Vozzi G, Ciardelli G, Ahluwalia A, Giusti P,. Genipin-crosslinked chitosan/gelatin blends for biomedical applications. J Mater Sci Mater Med 2008; 19: 889 -898.
13. Hillberg AL, Holmes CA, Tabrizian M,. Effect of genipin cross-linking on the cellular adhesion properties of layer-by-layer assembled polyelectrolyte films. Biomaterials 2009; 30: 4463 -4470.
14. Tsai CC, Huang RN, Sung HW, Liang HC,. In vitro evaluation of the genotoxicity of a naturally occurring crosslinking agent (genipin) for biologic tissue fixation. J Biomed Mater Res 2000; 52: 58 -65.
15. Silva SS, Motta A, Rodrigues MT, Pinheiro AFM, Gomes ME, Mano GF, Reis RL, Migliaresi C,. Novel genipin-cross-linked chitosan/silk fibroin sponges for cartilage engineering strategies. Biomacromolecules 2008; 9: 2764 -2774.
16. Yang MC, Wang SS, Chou NK, Chi NH, Huang YY, Chang YL, Shieh MJ, Chung TW,. The cardiomyogenic differentiation of rat mesenchymal stem cells on silk fibroin-polysaccharide cardiac patches in vitro. Biomaterials 2009; 30: 3757 -3765.
17. He W, Yong T, Teo WE, Ma ZW, Ramakrishna S,. Fabrication and endothelialization of collagen-blended biodegradable polymer nanofibers: Potential vascular graft for blood vessel tissue engineering. Tissue Eng 2005; 11: 1574 -1588.
18. Huang ZM, Zhang YZ, Ramakrishna S, Lim CT,. Electrospinning and mechanical characterization of gelatin nanofibers. Polymer 2004; 45: 5361 -5368.
19. Subbiah T, Bhat GS, Tock RW, Parameswaran S, Ramkumar SS,. Electrospinning of nanofibers. J Appl Polym Sci 2005; 96: 557 -569.
20. Chen X, Shao ZZ, Marinkovic NS, Miller LM, Zhou P, Chance MR,. Conformation transition kinetics of regenerated Bombyx mori silk fibroin membrane monitored by time-resolved FTIR spectroscopy. Biophys Chem 2001; 89: 25 -34.
21. Eichhorn SJ,., Sampson WW,. Statistical geometry of pores and statistics of porous nanofibrous assemblies. J R Soc Interf 2005; 2: 309 -318.
22. Li DP, Frey MW, Joo YL,. Characterization of nanofibrous membranes with capillary flow porometry. J Membr Sci 2006; 286: 104 -114.
23. Silva SS, Maniglio D, Motta A, Mano JF, Reis RL, Migliaresi C,. Genipin-modified silk-fibroin nanometric nets. Macromol Biosci 2008; 8: 766 -774.
24. Sundararaghavan HG, Monteiro GA, Lapin NA, Chabal YJ, Miksan JR, Shreiber DI,. Genipin-induced changes in collagen gels: Correlation of mechanical properties to -uorescence. J Biomed Mater Res A 2008; 87: 308 -320.
25. Sung HW, Chang Y, Chiu CT, Chen CN, Liang HC,. Crosslinking characteristics and mechanical properties of a bovine pericardium fixed with a naturally occurring crosslinking agent. J Biomed Mater Res A 1999; 47: 116 -126.
26. Sung HW, Chen CN, Huang RN, Hsu JC, Chang WH,. In vitro surface characterization of a biological patched with a naturally occurring crosslinking agent. Biomaterials 2000; 21: 1353 -1362.
27. Mi FL, Sung UW, Shyu SS,. Synthesis and characterization of a novel chitosan-based network prepared using naturally occurring crosslinker. J Polym Sci Part A: Polym Chem 2000; 38: 2804 -2814.
28. Kweon A, Ha HC, Um IC, Park YH,. Physical properties of silk fibroin/chitosan blend films. J Appl Polym Sci 2001; 80: 928 -934.
29. Magoshi J, Mizuide M, Magoshi Y,. Physical properties and structure of silk conformational changes in silk fibroin induced by immersion in water at 2 to 130°C. J Polym Sci: Polym Phys Ed 1979; 17: 515 -520.
30. Chen X, Shao ZZ, Marinkovic NS, Miller LM, Zhou P, Chance MR,. Conformation transition kinetics of regenerated Bombyx mori silk fibroin membrane monitored by time-resolved FTIR spectroscopy. Biophys Chem 2001; 89: 25 -34.
31. Touyama R, Takeda Y, Inoue K, Kawamura I, Yatsuzuka M, Ikumoto T, Shingu T, Yokoi T, Inouye H,. Studies on the blue pigments produced from genipin and methylamine. I. Structures of the brownish-red pigments, intermediates leading to the blue pigments. Chem Pharm Bull 1994; 42: 668 -673.
32. Zhou P, Li GY, Shao ZZ, Pan XY, Yu TY,. Structure of Bombyx mori silk fibroin based on the DFT chemical shift calculation. J Phys Chem B 2001; 105: 12469 -12476.
33. Oyrton AC, Monteiro J, Claudio A,. Some studies of crosslinking chitosan-glutaraldehyde interaction in a homogeneous system. Int J Biol Macromol 1999; 26: 119 -128.
34. Zhang YZ, Venugopal J, Huang ZM, Lim CT, Ramakrishna S,. Crosslinking of the electrospun gelatin nanofibers. Polymer 2006; 47: 2911 -2917.