Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibers

International Journal of Pharmaceutics

Volumn 397, Issue 1-2, 2010, Pages 50-58

  Natu, Mǎdǎlina V ^a   de Sousa, Hermínio C ^a   Gil, M H ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Bicomponent fibers; Drug release; Electrospinning; Modeling

Indexed keywords

ACETAZOLAMIDE; COPOLYMER; POLY(OXYETHYLENE B OXYPROPYLENE B OXYETHYLENE); POLYCAPROLACTONE; TIMOLOL MALEATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RELEASE; DRUG SOLUBILITY; ELECTROSPINNING; PRIORITY JOURNAL; WATER TRANSPORT;

ACETAZOLAMIDE; ADRENERGIC BETA-ANTAGONISTS; CARBONIC ANHYDRASE INHIBITORS; DELAYED-ACTION PREPARATIONS; DIFFUSION; DOSAGE FORMS; MODELS, THEORETICAL; PARTICLE SIZE; POLYMERS; SOLUBILITY; TIMOLOL; WATER;

EID: 77955985264     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.06.045     Document Type: Article

References (40)

1. Agarwal S., Wendorff J.H., Greiner A. Use of electrospinning technique for biomedical applications. Polymer 2008, 49:5603-5621.
2. ATHAS data bank, 2010. (accessed 09.03.2010). http://athas.prz.edu.pl/Default.aspx%3Fop=db.
3. Bogntizki M., Frese T., Steinhart M., Greiner A., Wendorff J.H. Preparation of fibers with nanoscaled morphologies: electrospinning of polymer blends. Polym. Eng. Sci. 2001, 10.1002/pen.10799.
4. Buschle-Diller G., Cooper J., Xie Z., Wu Y., Waldrup J., Ren X. Release of antibiotics from electrospun bicomponent fibers. Cellulose 2007, 10.1007/s10570-007-9183-3.
5. Casper C.L., Yamaguchi N., Kiick K.L., Rabolt J.F. Functionalizing electrospun fibers with biologically relevant macromolecules. Biomacromolecules 2005, 10.1021/bm050007e.
6. Casper C.L., Yang W., Farach-Carson M.C., Rabolt J.F. Coating electrospun collagen and gelatin fibers with perlecan domain I for increased growth factor binding. Biomacromolecules 2007, 10.1021/bm061003s.
7. Chew S.Y., Wen J., Yim E.K.F., Leong K.W. Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules 2005, 10.1021/bm0501149.
8. Cui W., Li X., Zhu X., Yu G., Zhou S., Weng J. Investigation of drug release and matrix degradation of electrospun poly(dl-lactide) fibers with paracetanol inoculation. Biomacromolecules 2006, 10.1021/bm060057z.
9. DrugBank database, 2010. Drug card for timolol (DB00373). (accessed 09.03.2010). http://www.drugbank.ca/drugs/DB00373.
10. DrugBank database, 2010. Drug card for acetazolamide (DB00819). (accessed 09.03.2010). http://www.drugbank.ca/drugs/DB00819.
11. Hglund A., Hakkarainen M., Albertsson A.-C. Degradation profile of poly(e{open}-caprolactone)-the influence of macroscopic and macromolecular biomaterial design. J. Macromol. Sci. Part A 2007, 44:1041-1046.
12. Huang Z.-M., Zhang Y.-Z., Kotaki M., Ramakrishna S. A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos. Sci. Technol. 2003, 63:2223-2253.
13. Hunley M.T., Long T.E. Electrospinning functional nanoscale fibers: a perspective for the future. Polym. Int. 2008, 57:385-389.
14. ImageJ, 2010. Image Processing and Analysis in Java. (accesed 09.03.2010). http://rsbweb.nih.gov/ij/.
15. Kalra V., Kakad P.A., Mendez S., Ivannikov T., Kamperman M., Joo Y.L. Self-assembled structures in electrospun poly(styrene-block-isoprene) fibers. Macromolecules 2006, 10.1021/ma052643a.
16. Kang M., Jung R., Kim H.-S., Jin H.-J. Preparation of superhydrophobic polystyrene membranes by electrospinning. Colloids Surf. A: Physicochem. Eng. Aspects 2008, 313-314:411-414.
17. Kenawy El-Refaie, Bowlin G.L., Mansfield K., Layman J., Simpson D.G., Sanders E.H., Wnek G.E. Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinylacetate), poly(lactic acid), and a blend. J. Control. Release 2002, 81:57-64.
18. Lee S.J., Yoo J.J., Lim G.J., Atala A., Stitzel J. In vitro evaluation of electrospun nanofiber scaffolds for vascular graft application. J. Biomed. Mater. Res. A 2007, 10.1002/jbm.a.31287.
19. 2 coating on electrospun polymer nanofibers. Adv. Mater. 2009, 10.1002/adma.200802458.
20. Ma Z., Kotaki M., Ramakrishna S. Surface modied nonwoven polysulphone (PSU) ber mesh by electrospinning: a novel afnity membrane. J. Membr. Sci. 2006, 10.1016/j.memsci.2005.07.038.
21. McClure M.J., Sell S.A., Ayres C.E., Simpson D.G., Bowlin G.L. Electrospinning-aligned and random polydioxanone-polycaprolactone-silk fibroin-blended scaffolds: geometry for a vascular matrix. Biomed. Mater. 2009, 10.1088/1748-6041/4/5/055010.
22. Miyajima M., Koshika A., Okada J., Ikeda M., Nishimura K. Effect of polymer crystallinity on papaverine release from poly(l-lactic acid) matrix. J. Control. Release 1997, 49:207-215.
23. Natu M.V., Gil M.H., de Sousa H.C. Supercritical solvent impregnation of poly(e{open}-caprolactone)/poly(oxyethylene-b-oxypropylene-b-oxyethylene) and poly(e{open}caprolactone)/poly(ethylene-vinyl acetate) blends for controlled release applications. J. Sup. Fluids 2008, 47:93-102.
24. Okuda T., Tominaga K., Kidoaki S. Time-programmed dual release formulation by multilayered drug-loaded nanober meshes. J. Control. Release 2009, 10.1016/j.jconrel.2009.12.029.
25. Peppas N.A., Brannon-Peppas L. Water diffusion sorption in amorphous macromolecular systems and foods. J. Food Eng. 1994, 22:189-210.
26. Pham Q.P., Sharma U., Mikos A.G. Electrospun poly(e-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules 2006, 10.1021/bm060680j.
27. Sawicka K.M., Gouma P. Electrospun composite nanofibers for functional applications. J. Nanoparticle Res. 2006, 10.1007/s11051-005-9026-9.
28. Srikar R., Yarin A.L., Megaridis C.M., Bazilevsky A.V., Kelley E. Desorption-limited mechanism of release from polymer nanofibers. Langmuir 2008, 24:965-974.
29. Taepaiboon P., Rungsardthong U., Supaphol P. Drug-loaded electrospun mats of poly(vinyl alcohol) fibres and their release characteristics of four model drugs. Nanotechnology 2006, 10.1088/0957-4484/17/9/041.
30. Thakur R.A., Florek C.A., Kohn J., Michniak B.B. Electrospun nanofibrous polymeric scaffold with targeted drug release profiles for potential application as wound dressing. Int. J. Pharm. 2008, 364:87-93.
31. Tsuji H., Ikada Y. Blends of aliphatic polyesters. II. Hydrolysis of solution-cast blends from poly(l-lactide) and Poly(e{open}-caprolactone) in phosphate-buffered solution. J. Appl. Polym. Sci. 1998, 67:405-415.
32. Tzafriri A.R. Mathematical modeling of diffusion-mediated release from bulk degrading matrices. J Control. Release 2000, 63:69-79.
33. Vaz C.M., van Tuijl S., Bouten C.V.C., Baaijens F.P.T. Design of scaffolds for blood vessel tissue engineering using a multi-layering electrospinning technique. Acta Biomater. 2005, 10.1016/j.actbio.2005.06.006.
34. Wei M., Kang B., Sung C., Mead J. Core-sheath structure in electrospun nanofibers from polymer blends. Macromol. Mater. Eng. 2006, 291:1307-1314. 10.1002/mame.200600284.
35. Xie Z., Buschle-Diller G. Electrospun poly(d,l-lactide) fibers for drug delivery: the influence of cosolvent and the mechanism of drug release. J. Appl. Polym. Sci. 2009, 10.1002/app.31026.
36. Xie J., Wang C.-H. Electrospun micro- and nanofibers for sustained delivery of paclitaxel to treat C6 glioma in vitro. Pharm. Res. 2006, 10.1007/s11095-006-9036-z.
37. Yu D.-G., Shen X.-X., Branford-White C., White K., Zhu L.-M., Annie Bligh S.W. Oral fast-dissolving drug delivery membranes prepared from electrospun polyvinylpyrrolidone ultrafine fibers. Nanotechnology 2009, 20:1-9.
38. Zamani M., Morshed M., Varshosaz J., Jannesari M. Controlled release of metronidazole benzoate from poly(e{open}-caprolactone) electrospun nanobers for periodontal diseases. Eur. J. Pharm. Biopharm. 2010, 10.1016/j.ejpb.2010.02.002.
39. Zeng J., Aigner A., Czubayko F., Kissel T., Wendorff J.H., Greiner A. Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. Biomacromolecules 2005, 10.1021/bm0492576.
40. Zeng J., Yang L., Liang Q., Zhang X., Guan H., Xu X., Chen X., Jin X. Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation. J. Control. Release 2005, 10.1016/j.jconrel.2005.02.024.