-
1
-
-
0347625839
-
Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5
-
Abramowitz J, Dai C, Hirschi KK, Dmitrieva RI, Doris PA, Liu L, and Allen JC (2003) Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5. Circulation 108:3048-3053.
-
(2003)
Circulation
, vol.108
, pp. 3048-3053
-
-
Abramowitz, J.1
Dai, C.2
Hirschi, K.K.3
Dmitrieva, R.I.4
Doris, P.A.5
Liu, L.6
Allen, J.C.7
-
2
-
-
67649870629
-
Low-dose digoxin and reduction in mortality and morbidity in heart failure
-
Ahmed A and Waagstein F (2009) Low-dose digoxin and reduction in mortality and morbidity in heart failure. Int J Cardiol 136:91-92.
-
(2009)
Int J Cardiol
, vol.136
, pp. 91-92
-
-
Ahmed, A.1
Waagstein, F.2
-
3
-
-
66149140549
-
A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT
-
Atkins KB, Irey B, Xiang N, and Brosius FC 3rd (2009) A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT. Am J Physiol Cell Physiol 296:C1151-C1161.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Atkins, K.B.1
Irey, B.2
Xiang, N.3
Brosius III, F.C.4
-
4
-
-
63849168850
-
Endogenous cardiotonic steroids: Physiology, pharmacology, and novel therapeutic targets
-
Bagrov AY, Shapiro JI, and Fedorova OV (2009) Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets. Pharmacol Rev 61:9-38.
-
(2009)
Pharmacol Rev
, vol.61
, pp. 9-38
-
-
Bagrov, A.Y.1
Shapiro, J.I.2
Fedorova, O.V.3
-
5
-
-
57649138736
-
Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: Current progress and future hurdles
-
Blazer LL and Neubig RR (2009) Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles. Neuropsychopharmacology 34:126-141.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 126-141
-
-
Blazer, L.L.1
Neubig, R.R.2
-
6
-
-
77956254304
-
Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins
-
Blazer LL, Roman DL, Chung A, Larsen MJ, Greedy BM, Husbands SM, and Neubig RR (2010) Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins. Mol Pharmacol 78:524-533.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 524-533
-
-
Blazer, L.L.1
Roman, D.L.2
Chung, A.3
Larsen, M.J.4
Greedy, B.M.5
Husbands, S.M.6
Neubig, R.R.7
-
7
-
-
79953878856
-
A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins
-
Blazer LL, Zhang H, Casey EM, Husbands SM, and Neubig RR (2011) A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins. Biochemistry 50:3181-3192.
-
(2011)
Biochemistry
, vol.50
, pp. 3181-3192
-
-
Blazer, L.L.1
Zhang, H.2
Casey, E.M.3
Husbands, S.M.4
Neubig, R.R.5
-
8
-
-
37549009153
-
Motor coordination deficits in mice lacking RGS9
-
Blundell J, Hoang CV, Potts B, Gold SJ, and Powell CM (2008) Motor coordination deficits in mice lacking RGS9. Brain Res 1190:78-85.
-
(2008)
Brain Res
, vol.1190
, pp. 78-85
-
-
Blundell, J.1
Hoang, C.V.2
Potts, B.3
Gold, S.J.4
Powell, C.M.5
-
9
-
-
33947371974
-
N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells
-
Bodenstein J, Sunahara RK, and Neubig RR (2007) N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells. Mol Pharmacol 71:1040-1050.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1040-1050
-
-
Bodenstein, J.1
Sunahara, R.K.2
Neubig, R.R.3
-
10
-
-
78049282918
-
Regulation of GPCR signaling in hypertension
-
Brinks HL and Eckhart AD (2010) Regulation of GPCR signaling in hypertension. Biochim Biophys Acta 1802:1268-1275.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 1268-1275
-
-
Brinks, H.L.1
Eckhart, A.D.2
-
11
-
-
4043103612
-
Increased expression of regulator of G protein signaling-2 (RGS-2) in Bartter's/Gitelman's syndrome. A role in the control of vascular tone and implication for hypertension
-
Calò LA, Pagnin E, Davis PA, Sartori M, Ceolotto G, Pessina AC, and Semplicini A (2004) Increased expression of regulator of G protein signaling-2 (RGS-2) in Bartter's/Gitelman's syndrome. a role in the control of vascular tone and implication for hypertension. J Clin Endocrinol Metab 89:4153-4157.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4153-4157
-
-
Calò, L.A.1
Pagnin, E.2
Davis, P.A.3
Sartori, M.4
Ceolotto, G.5
Pessina, A.C.6
Semplicini, A.7
-
12
-
-
33745561778
-
Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells
-
Cao X, Qin J, Xie Y, Khan O, Dowd F, Scofield M, Lin MF, and Tu Y (2006) Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells. Oncogene 25:3719-3734.
-
(2006)
Oncogene
, vol.25
, pp. 3719-3734
-
-
Cao, X.1
Qin, J.2
Xie, Y.3
Khan, O.4
Dowd, F.5
Scofield, M.6
Lin, M.F.7
Tu, Y.8
-
13
-
-
71749085915
-
Association and linkage analyses of RGS4 polymorphisms in schizophrenia
-
Chowdari KV, Mirnics K, Semwal P, Wood J, Lawrence E, Bhatia T, Deshpande SN, B K T, Ferrell RE, Middleton FA, et al. (2002) Association and linkage analyses of RGS4 polymorphisms in schizophrenia. Hum Mol Genet 11:1373-1380.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1373-1380
-
-
Chowdari, K.V.1
Mirnics, K.2
Semwal, P.3
Wood, J.4
Lawrence, E.5
Bhatia, T.6
Deshpande, S.N.7
T, B.K.8
Ferrell, R.E.9
Middleton, F.A.10
-
14
-
-
57149091336
-
Fine tuning of blood pressure by the regulator of G protein signaling (RGS) 2
-
da Costa Goncalves ACh, Luft FC, and Gross V (2008) Fine tuning of blood pressure by the regulator of G protein signaling (RGS) 2. J Am Soc Hypertens 2:403-409.
-
(2008)
J Am Soc Hypertens
, vol.2
, pp. 403-409
-
-
Da Costa Goncalves, A.Ch.1
Luft, F.C.2
Gross, V.3
-
15
-
-
0014108272
-
Comparative pharmacology of cardiac glycosides
-
Detweiler DK (1967) Comparative pharmacology of cardiac glycosides. Fed Proc 26:1119-1124.
-
(1967)
Fed Proc
, vol.26
, pp. 1119-1124
-
-
Detweiler, D.K.1
-
16
-
-
4344575064
-
Is RGS-2 a new drug development target in cardiovascular disease?
-
Doggrell SA (2004) Is RGS-2 a new drug development target in cardiovascular disease? Expert Opin Ther Targets 8:355-358.
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 355-358
-
-
Doggrell, S.A.1
-
17
-
-
0035803952
-
Profile of RGS expression in single rat atrial myocytes
-
Doupnik CA, Xu T, and Shinaman JM (2001) Profile of RGS expression in single rat atrial myocytes. Biochim Biophys Acta 1522:97-107.
-
(2001)
Biochim Biophys Acta
, vol.1522
, pp. 97-107
-
-
Doupnik, C.A.1
Xu, T.2
Shinaman, J.M.3
-
18
-
-
0029033981
-
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
-
Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, and Schreiber SL (1995) Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 268:726-731.
-
(1995)
Science
, vol.268
, pp. 726-731
-
-
Fenteany, G.1
Standaert, R.F.2
Lane, W.S.3
Choi, S.4
Corey, E.J.5
Schreiber, S.L.6
-
19
-
-
71749086540
-
Reconsidering the role for digoxin in the management of acute heart failure syndromes
-
Gheorghiade M and Braunwald E (2009) Reconsidering the role for digoxin in the management of acute heart failure syndromes. JAMA 302:2146-2147.
-
(2009)
JAMA
, vol.302
, pp. 2146-2147
-
-
Gheorghiade, M.1
Braunwald, E.2
-
20
-
-
37349018834
-
Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins
-
Gu S, Anton A, Salim S, Blumer KJ, Dessauer CW, and Heximer SP (2008) Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins. Mol Pharmacol 73:1-11.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1-11
-
-
Gu, S.1
Anton, A.2
Salim, S.3
Blumer, K.J.4
Dessauer, C.W.5
Heximer, S.P.6
-
21
-
-
78149355568
-
Renal actions of RGS2 control blood pressure
-
Gurley SB, Griffiths RC, Mendelsohn ME, Karas RH, and Coffman TM (2010) Renal actions of RGS2 control blood pressure. J Am Soc Nephrol 21:1847-1851.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1847-1851
-
-
Gurley, S.B.1
Griffiths, R.C.2
Mendelsohn, M.E.3
Karas, R.H.4
Coffman, T.M.5
-
22
-
-
43049122122
-
Regulation of G protein-coupled receptor signalling: Focus on the cardiovascular system and regulator of G protein signalling proteins
-
Hendriks-Balk MC, Peters SL, Michel MC, and Alewijnse AE (2008) Regulation of G protein-coupled receptor signalling: focus on the cardiovascular system and regulator of G protein signalling proteins. Eur J Pharmacol 585:278-291.
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 278-291
-
-
Hendriks-Balk, M.C.1
Peters, S.L.2
Michel, M.C.3
Alewijnse, A.E.4
-
23
-
-
0347706930
-
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
-
Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveirados-Santos A, Penninger JM, Muslin AJ, Steinberg TH, et al. (2003) Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. J Clin Invest 111:445-452.
-
(2003)
J Clin Invest
, vol.111
, pp. 445-452
-
-
Heximer, S.P.1
Knutsen, R.H.2
Sun, X.3
Kaltenbronn, K.M.4
Rhee, M.H.5
Peng, N.6
Oliveirados-Santos, A.7
Penninger, J.M.8
Muslin, A.J.9
Steinberg, T.H.10
-
24
-
-
0031474423
-
RGS2/G0S8 is a selective inhibitor of Gqα function
-
Heximer SP, Watson N, Linder ME, Blumer KJ, and Hepler JR (1997) RGS2/G0S8 is a selective inhibitor of Gqα function. Proc Natl Acad Sci USA 94:14389-14393.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14389-14393
-
-
Heximer, S.P.1
Watson, N.2
Linder, M.E.3
Blumer, K.J.4
Hepler, J.R.5
-
26
-
-
1642535435
-
Differentially regulated expression of endogenous RGS4 and RGS7
-
Krumins AM, Barker SA, Huang C, Sunahara RK, Yu K, Wilkie TM, Gold SJ, and Mumby SM (2004) Differentially regulated expression of endogenous RGS4 and RGS7. J Biol Chem 279:2593-2599.
-
(2004)
J Biol Chem
, vol.279
, pp. 2593-2599
-
-
Krumins, A.M.1
Barker, S.A.2
Huang, C.3
Sunahara, R.K.4
Yu, K.5
Wilkie, T.M.6
Gold, S.J.7
Mumby, S.M.8
-
27
-
-
78649416474
-
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: Clinical studies
-
Lanzani C, Citterio L, Glorioso N, Manunta P, Tripodi G, Salvi E, Carpini SD, Ferrandi M, Messaggio E, Staessen JA, et al. (2010) Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies. Sci Transl Med 2:59ra87.
-
(2010)
Sci Transl Med
, vol.2
-
-
Lanzani, C.1
Citterio, L.2
Glorioso, N.3
Manunta, P.4
Tripodi, G.5
Salvi, E.6
Carpini, S.D.7
Ferrandi, M.8
Messaggio, E.9
Staessen, J.A.10
-
28
-
-
27244444724
-
RGS4 and RGS5 are in vivo substrates of the N-end rule pathway
-
Lee MJ, Tasaki T, Moroi K, An JY, Kimura S, Davydov IV, and Kwon YT (2005) RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proc Natl Acad Sci USA 102:15030-15035.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15030-15035
-
-
Lee, M.J.1
Tasaki, T.2
Moroi, K.3
An, J.Y.4
Kimura, S.5
Davydov, I.V.6
Kwon, Y.T.7
-
29
-
-
79960693484
-
Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins
-
Lee PC, Sowa ME, Gygi SP, and Harper JW (2011) Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins. Mol Cell 43:392-405.
-
(2011)
Mol Cell
, vol.43
, pp. 392-405
-
-
Lee, P.C.1
Sowa, M.E.2
Gygi, S.P.3
Harper, J.W.4
-
30
-
-
33745864301
-
Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay
-
Liang M, Cai T, Tian J, Qu W, and Xie ZJ (2006) Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay. J Biol Chem 281:19709-19719.
-
(2006)
J Biol Chem
, vol.281
, pp. 19709-19719
-
-
Liang, M.1
Cai, T.2
Tian, J.3
Qu, W.4
Xie, Z.J.5
-
31
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔCT) method
-
Livak KJ and Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔCT) method. Methods 25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
32
-
-
69949131136
-
Translational control by RGS2
-
Nguyen CH, Ming H, Zhao P, Hugendubler L, Gros R, Kimball SR, and Chidiac P (2009) Translational control by RGS2. J Cell Biol 186:755-765.
-
(2009)
J Cell Biol
, vol.186
, pp. 755-765
-
-
Nguyen, C.H.1
Ming, H.2
Zhao, P.3
Hugendubler, L.4
Gros, R.5
Kimball, S.R.6
Chidiac, P.7
-
33
-
-
58849149464
-
Ouabain, a circulating hormone secreted by the adrenals, is pivotal in cardiovascular disease: Fact or fantasy?
-
Nicholls MG, Lewis LK, Yandle TG, Lord G, McKinnon W, and Hilton PJ (2009) Ouabain, a circulating hormone secreted by the adrenals, is pivotal in cardiovascular disease: fact or fantasy? J Hypertens 27:3-8.
-
(2009)
J Hypertens
, vol.27
, pp. 3-8
-
-
Nicholls, M.G.1
Lewis, L.K.2
Yandle, T.G.3
Lord, G.4
McKinnon, W.5
Hilton, P.J.6
-
34
-
-
77953016077
-
RGS2 inhibits beta-adrenergic receptor-induced cardiomyocyte hypertrophy
-
Nunn C, Zou MX, Sobiesiak AJ, Roy AA, Kirshenbaum LA, and Chidiac P (2010) RGS2 inhibits beta-adrenergic receptor-induced cardiomyocyte hypertrophy. Cell Signal 22:1231-1239.
-
(2010)
Cell Signal
, vol.22
, pp. 1231-1239
-
-
Nunn, C.1
Zou, M.X.2
Sobiesiak, A.J.3
Roy, A.A.4
Kirshenbaum, L.A.5
Chidiac, P.6
-
35
-
-
77955280187
-
Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblasts
-
Quintas LE, Pierre SV, Liu L, Bai Y, Liu X, and Xie ZJ (2010) Alterations of Na+/K+-ATPase function in caveolin-1 knockout cardiac fibroblasts. J Mol Cell Cardiol 49:525-531.
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 525-531
-
-
Quintas, L.E.1
Pierre, S.V.2
Liu, L.3
Bai, Y.4
Liu, X.5
Xie, Z.J.6
-
36
-
-
14844343100
-
Multi-tasking RGS proteins in the heart: The next therapeutic target?
-
Riddle EL, Schwartzman RA, Bond M, and Insel PA (2005) Multi-tasking RGS proteins in the heart: the next therapeutic target? Circ Res 96:401-411.
-
(2005)
Circ Res
, vol.96
, pp. 401-411
-
-
Riddle, E.L.1
Schwartzman, R.A.2
Bond, M.3
Insel, P.A.4
-
37
-
-
80053226559
-
Knockout of the Na,K-ATPase α2-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension
-
Rindler TN, Dostanic I, Lasko VM, Nieman ML, Neumann JC, Lorenz JN, and Lingrel JB (2011) Knockout of the Na,K-ATPase α2-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension. Am J Physiol Heart Circ Physiol 301:H1396-H1404.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Rindler, T.N.1
Dostanic, I.2
Lasko, V.M.3
Nieman, M.L.4
Neumann, J.C.5
Lorenz, J.N.6
Lingrel, J.B.7
-
38
-
-
33845301393
-
Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay
-
Roman DL, Talbot JN, Roof RA, Sunahara RK, Traynor JR, and Neubig RR (2007) Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol Pharmacol 71:169-175.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 169-175
-
-
Roman, D.L.1
Talbot, J.N.2
Roof, R.A.3
Sunahara, R.K.4
Traynor, J.R.5
Neubig, R.R.6
-
39
-
-
0033783132
-
GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
-
Ross EM and Wilkie TM (2000) GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu Rev Biochem 69:795-827.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 795-827
-
-
Ross, E.M.1
Wilkie, T.M.2
-
40
-
-
33947527882
-
Cardiac GPCRs: GPCR signaling in healthy and failing hearts
-
Salazar NC, Chen J, and Rockman HA (2007) Cardiac GPCRs: GPCR signaling in healthy and failing hearts. Biochim Biophys Acta 1768:1006-1018.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 1006-1018
-
-
Salazar, N.C.1
Chen, J.2
Rockman, H.A.3
-
41
-
-
0037844848
-
Identification of RGS2 and type v adenylyl cyclase interaction sites
-
Salim S, Sinnarajah S, Kehrl JH, and Dessauer CW (2003) Identification of RGS2 and type V adenylyl cyclase interaction sites. J Biol Chem 278:15842-15849.
-
(2003)
J Biol Chem
, vol.278
, pp. 15842-15849
-
-
Salim, S.1
Sinnarajah, S.2
Kehrl, J.H.3
Dessauer, C.W.4
-
42
-
-
18244412824
-
Distinct molecular phenotypes in murine cardiac muscle development, growth, and hypertrophy
-
Schoenfeld JR, Vasser M, Jhurani P, Ng P, Hunter JJ, Ross J Jr, Chien KR, and Lowe DG (1998) Distinct molecular phenotypes in murine cardiac muscle development, growth, and hypertrophy. J Mol Cell Cardiol 30:2269-2280.
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 2269-2280
-
-
Schoenfeld, J.R.1
Vasser, M.2
Jhurani, P.3
Ng, P.4
Hunter, J.J.5
Ross Jr., J.6
Chien, K.R.7
Lowe, D.G.8
-
43
-
-
77951298152
-
RGS2 expression and aldosterone:Renin ratio modulate response to drug therapy in hypertensive patients
-
Semplicini A, Strapazzon G, Papparella I, Sartori M, Realdi A, Macchini L, Calò LA, and Ceolotto G (2010) RGS2 expression and aldosterone:renin ratio modulate response to drug therapy in hypertensive patients. J Hypertens 28:1104-1108.
-
(2010)
J Hypertens
, vol.28
, pp. 1104-1108
-
-
Semplicini, A.1
Strapazzon, G.2
Papparella, I.3
Sartori, M.4
Realdi, A.5
Macchini, L.6
Calò, L.A.7
Ceolotto, G.8
-
45
-
-
77957240736
-
Regulators of G protein signaling proteins as targets for drug discovery
-
Sjögren B, Blazer LL, and Neubig RR (2010) Regulators of G protein signaling proteins as targets for drug discovery. Prog Mol Biol Transl Sci 91:81-119.
-
(2010)
Prog Mol Biol Transl Sci
, vol.91
, pp. 81-119
-
-
Sjögren, B.1
Blazer, L.L.2
Neubig, R.R.3
-
46
-
-
77957235831
-
Thinking outside of the "RGS box": New approaches to therapeutic targeting of regulators of G protein signaling
-
Sjögren B and Neubig RR (2010) Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling. Mol Pharmacol 78:550-557.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 550-557
-
-
Sjögren, B.1
Neubig, R.R.2
-
47
-
-
0001409028
-
The influence of some cations on an adenosine triphosphatase from peripheral nerves
-
Skou JC (1957) The influence of some cations on an adenosine triphosphatase from peripheral nerves. Biochim Biophys Acta 23:394-401.
-
(1957)
Biochim Biophys Acta
, vol.23
, pp. 394-401
-
-
Skou, J.C.1
-
48
-
-
14944383669
-
RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling
-
Sun X, Kaltenbronn KM, Steinberg TH, and Blumer KJ (2005) RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling. Mol Pharmacol 67:631-639.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 631-639
-
-
Sun, X.1
Kaltenbronn, K.M.2
Steinberg, T.H.3
Blumer, K.J.4
-
49
-
-
61749089404
-
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice
-
Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, et al. (2009) Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest 119:408-420.
-
(2009)
J Clin Invest
, vol.119
, pp. 408-420
-
-
Takimoto, E.1
Koitabashi, N.2
Hsu, S.3
Ketner, E.A.4
Zhang, M.5
Nagayama, T.6
Bedja, D.7
Gabrielson, K.L.8
Blanton, R.9
Siderovski, D.P.10
-
51
-
-
74949119587
-
Evidence for enhanced M3 muscarinic receptor function and sensitivity to atrial arrhythmia in the RGS2-deficient mouse
-
Tuomi JM, Chidiac P, and Jones DL (2010) Evidence for enhanced M3 muscarinic receptor function and sensitivity to atrial arrhythmia in the RGS2-deficient mouse. Am J Physiol Heart Circ Physiol 298:H554-H561.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Tuomi, J.M.1
Chidiac, P.2
Jones, D.L.3
-
52
-
-
84856877986
-
Small molecule inhibitors of regulator of G protein signalling (RGS) proteins
-
Turner EM, Blazer LL, Neubig RR, and Husbands SM (2012) Small molecule inhibitors of regulator of G protein signalling (RGS) proteins. ACS Med Chem Lett 3:146-150.
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 146-150
-
-
Turner, E.M.1
Blazer, L.L.2
Neubig, R.R.3
Husbands, S.M.4
-
54
-
-
2342487353
-
+-ATPase-mediated signal transduction: From protein interaction to cellular function
-
+-ATPase-mediated signal transduction: from protein interaction to cellular function. Mol Interv 3:157-168.
-
(2003)
Mol Interv
, vol.3
, pp. 157-168
-
-
Xie, Z.1
Cai, T.2
-
55
-
-
23344435021
-
Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population
-
Yang J, Kamide K, Kokubo Y, Takiuchi S, Tanaka C, Banno M, Miwa Y, Yoshii M, Horio T, Okayama A, et al. (2005) Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population. J Hypertens 23:1497-1505.
-
(2005)
J Hypertens
, vol.23
, pp. 1497-1505
-
-
Yang, J.1
Kamide, K.2
Kokubo, Y.3
Takiuchi, S.4
Tanaka, C.5
Banno, M.6
Miwa, Y.7
Yoshii, M.8
Horio, T.9
Okayama, A.10
-
56
-
-
0034785690
-
Inhibitory effects of digitalis on the proliferation of androgen dependent and independent prostate cancer cells
-
Yeh JY, Huang WJ, Kan SF, and Wang PS (2001) Inhibitory effects of digitalis on the proliferation of androgen dependent and independent prostate cancer cells. J Urol 166:1937-1942.
-
(2001)
J Urol
, vol.166
, pp. 1937-1942
-
-
Yeh, J.Y.1
Huang, W.J.2
Kan, S.F.3
Wang, P.S.4
-
57
-
-
79959893606
-
Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses
-
Zhang P, Su J, King ME, Maldonado AE, Park C, and Mende U (2011) Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses. Am J Physiol Heart Circ Physiol 301:H147-H156.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Zhang, P.1
Su, J.2
King, M.E.3
Maldonado, A.E.4
Park, C.5
Mende, U.6
-
58
-
-
33646842745
-
Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy
-
Zhang W, Anger T, Su J, Hao J, Xu X, Zhu M, Gach A, Cui L, Liao R, and Mende U (2006) Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy. J Biol Chem 281:5811-5820.
-
(2006)
J Biol Chem
, vol.281
, pp. 5811-5820
-
-
Zhang, W.1
Anger, T.2
Su, J.3
Hao, J.4
Xu, X.5
Zhu, M.6
Gach, A.7
Cui, L.8
Liao, R.9
Mende, U.10
-
59
-
-
0035013840
-
Regulator of G protein signaling proteins: Novel multifunctional drug targets
-
Zhong H and Neubig RR (2001) Regulator of G protein signaling proteins: novel multifunctional drug targets. J Pharmacol Exp Ther 297:837-845.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 837-845
-
-
Zhong, H.1
Neubig, R.R.2
-
60
-
-
33747037013
-
RGS2 is upregulated by and attenuates the hypertrophic effect of α1-adrenergic activation in cultured ventricular myocytes
-
Zou MX, Roy AA, Zhao Q, Kirshenbaum LA, Karmazyn M, and Chidiac P (2006) RGS2 is upregulated by and attenuates the hypertrophic effect of α1-adrenergic activation in cultured ventricular myocytes. Cell Signal 18:1655-1663.
-
(2006)
Cell Signal
, vol.18
, pp. 1655-1663
-
-
Zou, M.X.1
Roy, A.A.2
Zhao, Q.3
Kirshenbaum, L.A.4
Karmazyn, M.5
Chidiac, P.6
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