HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells

AIDS

Volumn 24, Issue 8, 2010, Pages 1107-1119

  Snyder, Alexandra ^a   Alsauskas, Zygimantas C ^a   Leventhal, Jeremy S ^a   Rosenstiel, Paul E ^a   Gong, Pengfei ^a   Chan, Justin Jk ^a   Barley, Kevin ^a   He, John C ^a   Klotman, Mary E ^a   Ross, Michael J ^a   Klotman, Paul E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

AIDS associated nephropathy; Apoptosis; Caspases; Extracellular signal regulated MAP kinases; Kidney; Vpr

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CASPASE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; LENTIVIRUS VECTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1 INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 2 INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BID; UNCLASSIFIED DRUG; VIRUS RNA; VPR PROTEIN;

ADULT; APOPTOSIS; ARTICLE; CELL TYPE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENETIC TRANSDUCTION; HIV ASSOCIATED NEPHROPATHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY TUBULE CELL; MEMBRANE POLARIZATION AND DEPOLARIZATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

AIDS-ASSOCIATED NEPHROPATHY; APOPTOSIS; CASPASE 8; CELL PROLIFERATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, VPR; HIV-1; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TUBULES; RNA, VIRAL; VIRUS REPLICATION;

EID: 77951878359     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328337b0ab     Document Type: Article

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