A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo

Carcinogenesis

Volumn 33, Issue 7, 2012, Pages 1421-1429

  Magkoufopoulou, C ^a,b   Claessen, S M H ^a   Tsamou, M ^a   Jennen, D G J ^a,b   Kleinjans, J C S ^a,b   Van delft, J H M ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; 8 QUINOLINOL; ACRYLIC ACID ETHYL ESTER; AFLATOXIN B1; AMPICILLIN; ANDROGEN RECEPTOR; ANTHRANILIC ACID; ASCORBIC ACID; BENZO[A]PYRENE; CURCUMIN; DICLOFENAC; DIETHYLSTILBESTROL; DIMETHYLNITROSAMINE; ESTRADIOL; GENOTOXIN; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HEPATOCYTE NUCLEAR FACTOR 6; MITOMYCIN C; N (2 FLUORENYL)ACETAMIDE; NONGENOTOXIN; PARACETAMOL; PHENACETIN; PHENOBARBITAL; PHENOL; QUERCETIN; RESORCINOL; SULFAFURAZOLE; TOXIC SUBSTANCE; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ACCURACY; AMES TEST; ARTICLE; BACTERIAL GENE; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE IDENTIFICATION; GENETIC MODEL; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS;

CELL LINE, TUMOR; GENE EXPRESSION REGULATION; HUMANS; MUTAGENICITY TESTS; MUTAGENS; TRANSCRIPTOME;

EID: 84865188988     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs182     Document Type: Article

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