Synergistic effects of SDF-1α chemokine and hyaluronic acid release from degradable hydrogels on directing bone marrow derived cell homing to the myocardium

Biomaterials

Volumn 33, Issue 31, 2012, Pages 7849-7857

  Purcell, Brendan P ^a   Elser, Jeremy A ^a,c   Mu, Anbin ^b,c   Margulies, Kenneth B ^b,c   Burdick, Jason A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Translational Research Center   (United States)

Author keywords

Bone marrow; Cardiac repair; Chemotaxis; Hyaluronic acid; Hydrogel; Stem cells

Indexed keywords

BONE MARROW; CARDIAC REPAIR; CHEMOKINES; CHEMOTAXIS; CROSS-LINKABLE; CROSSLINKED; CROSSLINKS; DEGRADABLE HYDROGEL; DISSOCIATION CONSTANT; ENGRAFTMENT; HYALURONIC ACIDS; IN-SITU FORMING; IN-VITRO; LOCAL EFFECTS; MACROMERS; MYOCARDIAL INFARCTION; RECEPTOR SIGNALING; SUSTAINED RELEASE; SYNERGISTIC EFFECT;

BIOCHEMISTRY; BONE; CYTOLOGY; DISSOCIATION; MOLECULES; ORGANIC ACIDS; STEM CELLS;

HYDROGELS;

CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; HYALURONIC ACID; STROMAL CELL DERIVED FACTOR 1ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL HOMING; CHEMOTAXIS; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE; HYDROGEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STATIC ELECTRICITY;

ANIMALS; BIODEGRADATION, ENVIRONMENTAL; BONE MARROW CELLS; CELL MOVEMENT; CHEMOKINE CXCL12; CHEMOTAXIS; CROSS-LINKING REAGENTS; HYALURONIC ACID; HYDROGELS; LIGHT; METHACRYLATES; MICE; MICE, INBRED BALB C; MYOCARDIUM; RECOMBINANT PROTEINS; STATIC ELECTRICITY;

MUS;

EID: 84865167921     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.07.005     Document Type: Article

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