Design, synthesis and evaluation of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 17, 2012, Pages 5363-5366

  Wang, Yan ^a   Damu, Guri L V ^a   Lv, Jing Song ^a   Geng, Rong Xia ^a   Yang, Da Cheng ^a   Zhou, Cheng He ^a  

^a SOUTHWEST UNIVERSITY   (China)

Author keywords

1,2,4 Triazole; Antibacterial; Antifungal; Clinafloxacin; Quinolone

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CHLORAMPHENICOL; CLINAFLOXACIN; CLINAFLOXACIN TRIAZOLE; FLUCONAZOLE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG EFFICACY; DRUG SYNTHESIS; ESCHERICHIA COLI; FUNGAL STRAIN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROCOCCUS LUTEUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; SHIGELLA DYSENTERIAE; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIAL INFECTIONS; DRUG DESIGN; FLUOROQUINOLONES; FUNGI; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MYCOSES; STAPHYLOCOCCAL INFECTIONS; TRIAZOLES;

FUNGI; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NEGIBACTERIA; POSIBACTERIA;

EID: 84865153151     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.07.064     Document Type: Article

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