메뉴 건너뛰기




Volumn 61, Issue 9, 2012, Pages 915-926

Acetylcholine and the alpha 7 nicotinic receptor: A potential therapeutic target for the treatment of periodontal disease?

Author keywords

Acetylcholine; Alpha 7 nicotinic receptor; Inflammation; Periodontal disease

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; 3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; 4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; ACETYLCHOLINE; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; BUNGAROTOXIN RECEPTOR; BUNGAROTOXIN RECEPTOR AGONIST; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; NICOTINE; SPIRO[1 AZABICYCLO[2.2.2]OCTANE 3,2' THIAZOLIDINE] 2' ONE; TC 7020; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84865123233     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-012-0513-z     Document Type: Review
Times cited : (24)

References (72)
  • 1
    • 28144438080 scopus 로고    scopus 로고
    • The condition of supporting structures
    • Walker A, Cooper I, editors. London: Stationary office Books
    • Kelly M SJ, Nuttall N et al. The condition of supporting structures. In: Walker A, Cooper I, editors. Adult dental health survey. Oral health in the United Kingdom, vol. 2000. London: Stationary office Books; 1998. p. 123-146.
    • (1998) Adult Dental Health Survey. Oral Health in the United Kingdom , vol.2000 , pp. 123-146
    • Kelly, M.S.J.1    Nuttall, N.2
  • 2
    • 49449085034 scopus 로고    scopus 로고
    • Cytokines that promote periodontal tissue destruction
    • Graves D. Cytokines that promote periodontal tissue destruction. J Periodontol. 2008;79:1585-91.
    • (2008) J Periodontol , vol.79 , pp. 1585-1591
    • Graves, D.1
  • 3
    • 49349105788 scopus 로고    scopus 로고
    • Host response modulation in periodontics
    • Preshaw PM. Host response modulation in periodontics. Periodontology. 2000;2008(48):92-110.
    • (2000) Periodontology. , vol.2008 , Issue.48 , pp. 92-110
    • Preshaw, P.M.1
  • 4
    • 40549128671 scopus 로고    scopus 로고
    • Basic and clinical aspects of non-neuronal acetylcholine: Expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy
    • DOI 10.1254/jphs.FM0070109
    • Fujii T, Takada-Takatori Y, Kawashima K. Basic and clinical aspects of non-neuronal acetylcholine: expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy. J Pharmacol Sci. 2008;106:186-92. (Pubitemid 351366336)
    • (2008) Journal of Pharmacological Sciences , vol.106 , Issue.2 , pp. 186-192
    • Fujii, T.1    Takada-Takatori, Y.2    Kawashima, K.3
  • 6
    • 49449094458 scopus 로고    scopus 로고
    • Acetylcholine beyond neurons: The non-neuronal cholinergic system in humans
    • Wessler I, Kirkpatrick CJ. Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans. Br J Pharmacol. 2008;154:1558-71.
    • (2008) Br J Pharmacol , vol.154 , pp. 1558-1571
    • Wessler, I.1    Kirkpatrick, C.J.2
  • 7
    • 0002687960 scopus 로고    scopus 로고
    • Identification of acetylcholine and related esters of biological origin
    • Eichler O, Farah A, Koelle GB, editors.
    • VP W. Identification of acetylcholine and related esters of biological origin. In: Eichler O, Farah A, Koelle GB, editors. Handbuch Der Experimentellen Pharmakologie., vol. 15; p. 1-39.
    • Handbuch der Experimentellen Pharmakologie. , vol.15 , pp. 1-39
    • W, V.P.1
  • 8
    • 0037470640 scopus 로고    scopus 로고
    • The non-neuronal cholinergic system in humans: Expression, function and pathophysiology
    • DOI 10.1016/S0024-3205(03)00083-3
    • Wessler I, Kilbinger H, Bittinger F, Unger R, Kirkpatrick CJ. The non-neuronal cholinergic system in humans: expression, function and pathophysiology. Life Sci. 2003;72:2055-61. (Pubitemid 36298947)
    • (2003) Life Sciences , vol.72 , Issue.18-19 , pp. 2055-2061
    • Wessler, I.1    Kilbinger, H.2    Bittinger, F.3    Unger, R.4    Kirkpatrick, C.J.5
  • 9
    • 40549097040 scopus 로고    scopus 로고
    • Basic and clinical aspects of non-neuronal acetylcholine: Overview of non-neuronal cholinergic systems and their biological significance
    • DOI 10.1254/jphs.FM0070073
    • Kawashima K, Fujii T. Basic and clinical aspects of non-neuronal acetylcholine: overview of non-neuronal cholinergic systems and their biological significance. J Pharmacol Sci. 2008;106:167-73. (Pubitemid 351366333)
    • (2008) Journal of Pharmacological Sciences , vol.106 , Issue.2 , pp. 167-173
    • Kawashima, K.1    Fujii, T.2
  • 12
    • 33749440087 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors
    • DOI 10.2174/138161206778522056
    • Ishii M, Kurachi Y. Muscarinic acetylcholine receptors. Curr Pharm Des. 2006;12:3573-81. (Pubitemid 44509627)
    • (2006) Current Pharmaceutical Design , vol.12 , Issue.28 , pp. 3573-3581
    • Ishii, M.1    Kurachi, Y.2
  • 13
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: From structure to function
    • Albuquerque EX, Pereira EF, Alkondon M, Rogers SW. Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol Rev. 2009;89:73-120.
    • (2009) Physiol Rev , vol.89 , pp. 73-120
    • Albuquerque, E.X.1    Pereira, E.F.2    Alkondon, M.3    Rogers, S.W.4
  • 15
    • 0036867440 scopus 로고    scopus 로고
    • An in vitro model of ciprofloxacin and minocycline transport by oral epithelial cells
    • DOI 10.1902/jop.2002.73.11.1267
    • Brayton JJ, Yang Q, Nakkula RJ, Walters JD. An in vitro model of ciprofloxacin and minocycline transport by oral epithelial cells. J Periodontol. 2002;73:1267-72. (Pubitemid 35469673)
    • (2002) Journal of Periodontology , vol.73 , Issue.11 , pp. 1267-1272
    • Brayton, J.J.1    Yang, Q.2    Nakkula, R.J.3    Walters, J.D.4
  • 17
    • 0025415577 scopus 로고
    • Cholinergic components in human gingiva in healthy and inflamed states
    • Rajeswari KR, Satyanarayana M. Cholinergic components in human gingiva in healthy and inflamed states. Indian J Dent Res. 1990;2:166-9.
    • (1990) Indian J Dent Res , vol.2 , pp. 166-169
    • Rajeswari, K.R.1    Satyanarayana, M.2
  • 18
    • 0037608959 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors regulating cell cycle progression are expressed in human gingival keratinocytes
    • DOI 10.1034/j.1600-0765.2003.01006.x
    • Arredondo J, Hall LL, Ndoye A, Chernyavsky AI, Jolkovsky DL, Grando SA. Muscarinic acetylcholine receptors regulating cell cycle progression are expressed in human gingival keratinocytes. J Periodontal Res. 2003;38:79-89. (Pubitemid 37463601)
    • (2003) Journal of Periodontal Research , vol.38 , Issue.1 , pp. 79-89
    • Arredondo, J.1    Hall, L.L.2    Ndoye, A.3    Chernyavsky, A.I.4    Jolkovsky, D.L.5    Grando, S.A.6
  • 19
    • 77953231627 scopus 로고    scopus 로고
    • Functional expression of alpha 7 nicotinic acetylcholine receptors in human periodontal ligament fibroblasts and rat periodontal tissues
    • Wang XJ, Liu YF, Wang QY, et al. Functional expression of alpha 7 nicotinic acetylcholine receptors in human periodontal ligament fibroblasts and rat periodontal tissues. Cell Tissue Res. 2010;340:347-55.
    • (2010) Cell Tissue Res , vol.340 , pp. 347-355
    • Wang, X.J.1    Liu, Y.F.2    Wang, Q.Y.3
  • 20
    • 69249088563 scopus 로고    scopus 로고
    • Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes
    • Thangjam GS, Kondaiah P. Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes. J Periodontal Res. 2009;44:673-82.
    • (2009) J Periodontal Res , vol.44 , pp. 673-682
    • Thangjam, G.S.1    Kondaiah, P.2
  • 21
    • 62649115017 scopus 로고    scopus 로고
    • Transglutaminase-2 regulation by arecoline in gingival fibroblasts
    • Thangjam GS, Agarwal P, Khan I, et al. Transglutaminase-2 regulation by arecoline in gingival fibroblasts. J Dent Res. 2009;88:170-5.
    • (2009) J Dent Res , vol.88 , pp. 170-175
    • Thangjam, G.S.1    Agarwal, P.2    Khan, I.3
  • 22
    • 33750135226 scopus 로고    scopus 로고
    • Receptor-mediated tobacco toxicity: Cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of α7 nicotinic receptor in oral keratinocytes
    • DOI 10.1096/fj.06-6191com
    • Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes. FASEB J. 2006;20:2093-101. (Pubitemid 44953908)
    • (2006) FASEB Journal , vol.20 , Issue.12 , pp. 2093-2101
    • Arredondo, J.1    Chernyavsky, A.I.2    Jolkovsky, D.L.3    Pinkerton, K.E.4    Grando, S.A.5
  • 23
    • 43249120398 scopus 로고    scopus 로고
    • Receptor-mediated tobacco toxicity: Acceleration of sequential expression of α5 and α7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke
    • DOI 10.1096/fj.07-9965.com
    • Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke. FASEB J. 2008;22:1356-68. (Pubitemid 351656777)
    • (2008) FASEB Journal , vol.22 , Issue.5 , pp. 1356-1368
    • Arredondo, J.1    Chernyavsky, A.I.2    Jolkovsky, D.L.3    Pinkerton, K.E.4    Grando, S.A.5
  • 24
    • 34249704581 scopus 로고    scopus 로고
    • Receptor-mediated tobacco toxicity: Alterations of the NF-κB expression and activity downstream of α7 nicotinic receptor in oral keratinocytes
    • DOI 10.1016/j.lfs.2007.01.013, PII S0024320507000537, Proceedings of the 2nd International Symposium on Non-neuronal Acetylcholine
    • Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes. Life Sci. 2007;80:2191-4. (Pubitemid 46824132)
    • (2007) Life Sciences , vol.80 , Issue.24-25 , pp. 2191-2194
    • Arredondo, J.1    Chernyavsky, A.I.2    Jolkovsky, D.L.3    Pinkerton, K.E.4    Grando, S.A.5
  • 25
    • 0142178155 scopus 로고    scopus 로고
    • The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation
    • Pavlov VA, Wang H, Czura CJ, Friedman SG, Tracey KJ. The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Mol Med. 2003;9:125-34. (Pubitemid 37310949)
    • (2003) Molecular Medicine , vol.9 , Issue.5-8 , pp. 125-134
    • Pavlov, V.A.1    Wang, H.2    Czura, C.J.3    Friedman, S.G.4    Tracey, K.J.5
  • 28
    • 73949141883 scopus 로고    scopus 로고
    • Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury
    • Su X, Matthay MA, Malik AB. Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury. J Immunol. 2010;184:401-10.
    • (2010) J Immunol , vol.184 , pp. 401-410
    • Su, X.1    Matthay, M.A.2    Malik, A.B.3
  • 30
    • 79953703686 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptors as novel therapeutic targets for inflammationbased diseases
    • Bencherif M, Lippiello PM, Lucas R, Marrero MB. Alpha7 nicotinic receptors as novel therapeutic targets for inflammationbased diseases. Cell Mol Life Sci. 2011;68:931-49.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 931-949
    • Bencherif, M.1    Lippiello, P.M.2    Lucas, R.3    Marrero, M.B.4
  • 31
    • 51849148885 scopus 로고    scopus 로고
    • Inhibition of the development of collagen-induced arthritis in Wistar rats through vagus nerve suspension: A 3-month observation
    • Zhang P, Han D, Tang T, Zhang X, Dai K. Inhibition of the development of collagen-induced arthritis in Wistar rats through vagus nerve suspension: a 3-month observation. Inflamm Res. 2008;57:322-8.
    • (2008) Inflamm Res , vol.57 , pp. 322-328
    • Zhang, P.1    Han, D.2    Tang, T.3    Zhang, X.4    Dai, K.5
  • 32
    • 77953542271 scopus 로고    scopus 로고
    • The vagus nerve and nicotinic receptors involve inhibition of HMGB1 release and early proinflammatory cytokines function in collagen-induced arthritis
    • Li T, Zuo X, Zhou Y, et al. The vagus nerve and nicotinic receptors involve inhibition of HMGB1 release and early proinflammatory cytokines function in collagen-induced arthritis. J Clin Immunol. 2010;30:213-20.
    • J Clin Immunol. , vol.2010 , Issue.30 , pp. 213-220
    • Li, T.1    Zuo, X.2    Zhou, Y.3
  • 33
    • 58249121600 scopus 로고    scopus 로고
    • Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice
    • van Maanen MA, Lebre MC, van der Poll T, et al. Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice. Arthritis Rheum. 2009;60:114-22.
    • (2009) Arthritis Rheum. , vol.60 , pp. 114-122
    • Van Maanen, M.A.1    Lebre, M.C.2    Van Der Poll, T.3
  • 34
    • 55849118078 scopus 로고    scopus 로고
    • Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor
    • Waldburger JM, Boyle DL, Pavlov VA, Tracey KJ, Firestein GS. Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor. Arthritis Rheum. 2008;58:3439-49.
    • (2008) Arthritis Rheum , vol.58 , pp. 3439-3449
    • Waldburger, J.M.1    Boyle, D.L.2    Pavlov, V.A.3    Tracey, K.J.4    Firestein, G.S.5
  • 35
    • 67651246901 scopus 로고    scopus 로고
    • Cell specific synovial expression of nicotinic alpha 7 acetylcholine receptor in rheumatoid arthritis and psoriatic arthritis
    • Westman M, Engstrom M, Catrina AI, Lampa J. Cell specific synovial expression of nicotinic alpha 7 acetylcholine receptor in rheumatoid arthritis and psoriatic arthritis. Scand J Immunol. 2009;70:136-40.
    • (2009) Scand J Immunol , vol.70 , pp. 136-140
    • Westman, M.1    Engstrom, M.2    Catrina, A.I.3    Lampa, J.4
  • 36
    • 66049108135 scopus 로고    scopus 로고
    • The alpha7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation
    • van Maanen MA, Stoof SP, van der Zanden EP, et al. The alpha7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: a possible role for a key neurotransmitter in synovial inflammation. Arthritis Rheum. 2009;60:1272-81.
    • (2009) Arthritis Rheum. , vol.60 , pp. 1272-1281
    • Van Maanen, M.A.1    Stoof, S.P.2    Van Der Zanden, E.P.3
  • 37
    • 77956034589 scopus 로고    scopus 로고
    • Role of the cholinergic nervous system in rheumatoid arthritis: Aggravation of arthritis in nicotinic acetylcholine receptor alpha7 subunit gene knockout mice
    • van Maanen MA, Stoof SP, Larosa GJ, Vervoordeldonk MJ, Tak PP. Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor alpha7 subunit gene knockout mice. Ann Rheum Dis. 2010;69:1717-23.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1717-1723
    • Van Maanen, M.A.1    Stoof, S.P.2    Larosa, G.J.3    Vervoordeldonk, M.J.4    Tak, P.P.5
  • 38
    • 77956524955 scopus 로고    scopus 로고
    • Lack of acetylcholine nicotine alpha 7 receptor suppresses development of collageninduced arthritis and adaptive immunity
    • Westman M, Saha S, Morshed M, Lampa J. Lack of acetylcholine nicotine alpha 7 receptor suppresses development of collageninduced arthritis and adaptive immunity. Clin Exp Immunol. 2010;162(1):62-67.
    • (2010) Clin Exp Immunol , vol.162 , Issue.1 , pp. 62-67
    • Westman, M.1    Saha, S.2    Morshed, M.3    Lampa, J.4
  • 39
    • 34347258134 scopus 로고    scopus 로고
    • Autonomic innervation and regulation of the immune system (1987-2007)
    • DOI 10.1016/j.bbi.2007.03.008, PII S088915910700075X
    • Nance DM, Sanders VM. Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav Immun. 2007;21:736-45. (Pubitemid 47002215)
    • (2007) Brain, Behavior, and Immunity , vol.21 , Issue.6 , pp. 736-745
    • Nance, D.M.1    Sanders, V.M.2
  • 40
    • 33745260688 scopus 로고    scopus 로고
    • Neural-immune interface in the rat area postrema
    • DOI 10.1016/j.neuroscience.2006.03.048, PII S0306452206003745
    • Goehler LE, Erisir A, Gaykema RP. Neural-immune interface in the rat area postrema. Neuroscience. 2006;140:1415-34. (Pubitemid 43928278)
    • (2006) Neuroscience , vol.140 , Issue.4 , pp. 1415-1434
    • Goehler, L.E.1    Erisir, A.2    Gaykema, R.P.A.3
  • 42
    • 77953508463 scopus 로고    scopus 로고
    • Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis
    • Bruchfeld A, Goldstein RS, Chavan S, et al. Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis. J Intern Med. 2010;268:94-101.
    • (2010) J Intern Med , vol.268 , pp. 94-101
    • Bruchfeld, A.1    Goldstein, R.S.2    Chavan, S.3
  • 43
    • 34249285850 scopus 로고    scopus 로고
    • The non-neuronal cholinergic system in peripheral blood cells: Effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory burst and migration
    • DOI 10.1016/j.lfs.2007.01.010, PII S0024320507000446, Proceedings of the 2nd International Symposium on Non-neuronal Acetylcholine
    • Neumann S, Razen M, Habermehl P, et al. The non-neuronal cholinergic system in peripheral blood cells: effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory burst and migration. Life Sci. 2007;80:2361-4. (Pubitemid 46818263)
    • (2007) Life Sciences , vol.80 , Issue.24-25 , pp. 2361-2364
    • Neumann, S.1    Razen, M.2    Habermehl, P.3    Meyer, C.U.4    Zepp, F.5    Kirkpatrick, C.J.6    Wessler, I.7
  • 44
    • 77951668745 scopus 로고    scopus 로고
    • Inhibition of Toll-like receptor 2-mediated interleukin-8 production in Cystic Fibrosis airway epithelial cells via the alpha7- nicotinic acetylcholine receptor
    • Greene CM, Ramsay H, Wells RJ, O'Neill SJ, McElvaney NG. Inhibition of Toll-like receptor 2-mediated interleukin-8 production in Cystic Fibrosis airway epithelial cells via the alpha7- nicotinic acetylcholine receptor. Mediators Inflamm. 2010;2010:423241
    • (2010) Mediators Inflamm. , vol.2010 , pp. 423241
    • Greene, C.M.1    Ramsay, H.2    Wells, R.J.3    O'Neill, S.J.4    McElvaney, N.G.5
  • 45
    • 0037470621 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subunits and receptor activity in the epithelial cell line HT29
    • DOI 10.1016/S0024-3205(03)00089-4
    • Summers AE, Whelan CJ, Parsons ME. Nicotinic acetylcholine receptor subunits and receptor activity in the epithelial cell line HT29. Life Sci. 2003;72:2091-4. (Pubitemid 36298952)
    • (2003) Life Sciences , vol.72 , Issue.18-19 , pp. 2091-2094
    • Summers, A.E.1    Whelan, C.J.2    Parsons, M.E.3
  • 46
    • 79959483170 scopus 로고    scopus 로고
    • Nicotine reduces TNF-alpha expression through a alpha7 nAChR/MyD88/NF-kB pathway in HBE16 airway epithelial cells
    • Li Q, Zhou XD, Kolosov VP, Perelman JM. Nicotine reduces TNF-alpha expression through a alpha7 nAChR/MyD88/NF-kB pathway in HBE16 airway epithelial cells. Cell Physiol Biochem. 2011;27:605-12.
    • (2011) Cell Physiol Biochem , vol.27 , pp. 605-612
    • Li, Q.1    Zhou, X.D.2    Kolosov, V.P.3    Perelman, J.M.4
  • 47
    • 9844244026 scopus 로고    scopus 로고
    • Identification of nicotinic acetylcholine receptors on lymphocytes in the periphery as well as thymus in mice
    • Toyabe S, Iiai T, Fukuda M, et al. Identification of nicotinic acetylcholine receptors on lymphocytes in the periphery as well as thymus in mice. Immunology. 1997;92:201-5. (Pubitemid 27428447)
    • (1997) Immunology , vol.92 , Issue.2 , pp. 201-205
    • Toyabe, S.1    Hai, T.2    Fukuda, M.3    Kawamura, T.4    Suzuki, S.5    Uchiyama, M.6    Abo, T.7
  • 48
    • 33748713337 scopus 로고    scopus 로고
    • Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-κB phosphorylation and nuclear factor-κB transcriptional activity through nicotinic acetylcholine receptor α7
    • DOI 10.1111/j.1365-2249.2006.03169.x
    • Yoshikawa H, Kurokawa M, Ozaki N, et al. Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of I-kappaB phosphorylation and nuclear factorkappaB transcriptional activity through nicotinic acetylcholine receptor alpha7. Clin Exp Immunol. 2006;146:116-23. (Pubitemid 44393846)
    • (2006) Clinical and Experimental Immunology , vol.146 , Issue.1 , pp. 116-123
    • Yoshikawa, H.1    Kurokawa, M.2    Ozaki, N.3    Nara, K.4    Atou, K.5    Takada, E.6    Kamochi, H.7    Suzuki, N.8
  • 51
    • 80052661771 scopus 로고    scopus 로고
    • Cytokine-induced alterations of alpha7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis
    • Galitovskiy V, Qian J, Chernyavsky AI, et al. Cytokine-induced alterations of alpha7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis. J Immunol. 2011;187: 2677-87.
    • (2011) J Immunol , vol.187 , pp. 2677-2687
    • Galitovskiy, V.1    Qian, J.2    Chernyavsky, A.I.3
  • 52
    • 77649341442 scopus 로고    scopus 로고
    • Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses
    • Nizri E, Irony-Tur-Sinai M, Lory O, Orr-Urtreger A, Lavi E, Brenner T. Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. J Immunol. 2009;183:6681-8.
    • (2009) J Immunol , vol.183 , pp. 6681-6688
    • Nizri, E.1    Irony-Tur-Sinai, M.2    Lory, O.3    Orr-Urtreger, A.4    Lavi, E.5    Brenner, T.6
  • 53
    • 78649572256 scopus 로고    scopus 로고
    • Stimulation of alpha7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4?CD25? regulatory T cells in mice in vitro
    • Wang DW, Zhou RB, Yao YM, et al. Stimulation of alpha7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4?CD25? regulatory T cells in mice in vitro. J Pharmacol Exp Ther. 2010;335:553-61.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 553-561
    • Wang, D.W.1    Zhou, R.B.2    Yao, Y.M.3
  • 54
    • 80053593864 scopus 로고    scopus 로고
    • Acetylcholinesynthesizing T cells relay neural signals in a vagus nerve circuit
    • Rosas-Ballina M, Olofsson PS, Ochani M, et al. Acetylcholinesynthesizing T cells relay neural signals in a vagus nerve circuit. Science. 2011;334:98-101.
    • (2011) Science. , vol.334 , pp. 98-101
    • Rosas-Ballina, M.1    Olofsson, P.S.2    Ochani, M.3
  • 55
    • 79955476932 scopus 로고    scopus 로고
    • Plasticity of the murine spleen T-cell cholinergic receptors and their role in in vitro differentiation of naive CD4 T cells toward the Th1, Th2 and Th17 lineages
    • Qian J, Galitovskiy V, Chernyavsky AI, Marchenko S, Grando SA. Plasticity of the murine spleen T-cell cholinergic receptors and their role in in vitro differentiation of naive CD4 T cells toward the Th1, Th2 and Th17 lineages. Genes Immun. 2011; 12:222-30.
    • (2011) Genes Immun , vol.12 , pp. 222-230
    • Qian, J.1    Galitovskiy, V.2    Chernyavsky, A.I.3    Marchenko, S.4    Grando, S.A.5
  • 58
    • 34249337063 scopus 로고    scopus 로고
    • The role of nicotinic receptors in B-lymphocyte development and activation
    • DOI 10.1016/j.lfs.2007.02.005, PII S0024320507001531, Proceedings of the 2nd International Symposium on Non-neuronal Acetylcholine
    • Skok MV, Grailhe R, Agenes F, Changeux JP. The role of nicotinic receptors in B-lymphocyte development and activation. Life Sci. 2007;80:2334-6. (Pubitemid 46818278)
    • (2007) Life Sciences , vol.80 , Issue.24-25 , pp. 2334-2336
    • Skok, M.V.1    Grailhe, R.2    Agenes, F.3    Changeux, J.-P.4
  • 60
    • 79952100582 scopus 로고    scopus 로고
    • Differential involvement of alpha4beta2, alpha7 and alpha9alpha10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro
    • Koval L, Lykhmus O, Zhmak M, et al. Differential involvement of alpha4beta2, alpha7 and alpha9alpha10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro. Int J Biochem Cell Biol. 2011;43:516-24.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 516-524
    • Koval, L.1    Lykhmus, O.2    Zhmak, M.3
  • 61
    • 33745483860 scopus 로고    scopus 로고
    • Suppression of overt gingival inflammation in tobacco smokers clinical and mechanistic considerations
    • Scott DA, Singer DL. Suppression of overt gingival inflammation in tobacco smokers clinical and mechanistic considerations. Int J Dent Hygiene. 2004;2:104-10.
    • (2004) Int J Dent Hygiene , vol.2 , pp. 104-110
    • Scott, D.A.1    Singer, D.L.2
  • 62
    • 84860223257 scopus 로고    scopus 로고
    • Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1b or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signaling
    • Kashiwagi Y, Yanagita M, Kojima Y, et al. Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1b or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signaling. Arch Oral Biol. 2011;57(5):483-90.
    • (2011) Arch Oral Biol , vol.57 , Issue.5 , pp. 483-490
    • Kashiwagi, Y.1    Yanagita, M.2    Kojima, Y.3
  • 64
    • 65349141209 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor activation mediates nicotineinduced enhancement of experimental periodontitis
    • Breivik T, Gundersen Y, Gjermo P, von Horsten S, Opstad PK. Nicotinic acetylcholine receptor activation mediates nicotineinduced enhancement of experimental periodontitis. J Periodontal Res. 2009;44:297-304.
    • (2009) J Periodontal Res , vol.44 , pp. 297-304
    • Breivik, T.1    Gundersen, Y.2    Gjermo, P.3    Von Horsten, S.4    Opstad, P.K.5
  • 67
    • 33646522174 scopus 로고    scopus 로고
    • The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice
    • van Westerloo DJ, Giebelen IA, Florquin S, et al. The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice. Gastroenterology. 2006;130:1822-30.
    • (2006) Gastroenterology. , vol.130 , pp. 1822-1830
    • Van Westerloo, D.J.1    Giebelen, I.A.2    Florquin, S.3
  • 70
    • 21744458277 scopus 로고    scopus 로고
    • Modulation of airway inflammation and resistance in mice by a nicotinic receptor agonist
    • DOI 10.1183/09031936.05.00116104
    • Blanchet MR, Israel-Assayag E, Cormier Y. Modulation of airway inflammation and resistance in mice by a nicotinic receptor agonist. Eur Respir J. 2005;26:21-7. (Pubitemid 40945927)
    • (2005) European Respiratory Journal , vol.26 , Issue.1 , pp. 21-27
    • Blanchet, M.-R.1    Israel-Assayag, E.2    Cormier, Y.3
  • 71
    • 73949111377 scopus 로고    scopus 로고
    • An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes
    • Marrero MB, Lucas R, Salet C, et al. An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes. J Pharmacol Exp Ther. 2010;332:173-80.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 173-180
    • Marrero, M.B.1    Lucas, R.2    Salet, C.3
  • 72
    • 48749124897 scopus 로고    scopus 로고
    • The epithelial cholinergic system of the airways
    • Kummer W, Lips KS, Pfeil U. The epithelial cholinergic system of the airways. Histochem Cell Biol. 2008;130:219-34.
    • (2008) Histochem Cell Biol , vol.130 , pp. 219-234
    • Kummer, W.1    Lips, K.S.2    Pfeil, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.