Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis

Journal of Internal Medicine

Volumn 268, Issue 1, 2010, Pages 94-101

  Bruchfeld, A ^a,b   Goldstein, R S ^b,c   Chavan, S ^b   Patel, N B ^b   Rosas Ballina, M ^b   Kohn, N ^d   Qureshi, A R ^a   Tracey, K J ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Laboratory of Biomedical Science   (Sweden)

^c Department of Emergency Medicine ^*  (Sweden)

^d FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Autonomic dysfunction; Cholinergic agonists; LPS; Monocyte cytokine attenuation; RA

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; COLLAGEN; CORTICOSTEROID; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ENDOTOXIN; NICOTINIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD; BLOOD CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HEART RATE VARIABILITY; HUMAN; INFLAMMATORY CELL; MALE; NERVE CONDUCTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RR INTERVAL; VAGUS NERVE;

ADULT; AGED; ARTHRITIS, RHEUMATOID; BENZYLIDENE COMPOUNDS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CHOLINERGIC AGONISTS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HEART RATE; HMGB1 PROTEIN; HUMANS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; NICOTINE; PROSPECTIVE STUDIES; PYRIDINES; RECEPTORS, NICOTINIC; TISSUE CULTURE TECHNIQUES; TUMOR NECROSIS FACTOR-ALPHA; VAGUS NERVE;

EID: 77953508463     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2010.02226.x     Document Type: Article

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