Perlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo

Clinical and Experimental Metastasis

Volumn 22, Issue 5, 2005, Pages 377-390

  Savorè, Cristiana ^a   Zhang, Chu ^a   Muir, Caroline ^a   Liu, Riting ^a   Wyrwa, Jeffrey ^a   Shu, Jun ^b   Zhau, Haiyen E ^b   Chung, Leland W K ^b   Carson, Daniel D ^a   Farach Carson, Mary C ^a  

^a UNIVERSITY OF DELAWARE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Extracellular matrix; Heparin binding growth factors; Perlecan; Prostate cancer; Ribozyme

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; MESSENGER RNA; PERLECAN; PROTEOHEPARAN SULFATE; SOMATOMEDIN C; VASCULOTROPIN A;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BLOOD ANALYSIS; CANCER CELL; CANCER GROWTH; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; EXPERIMENTAL MOUSE; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; GROWTH RATE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; ISOLATION PROCEDURE; METASTASIS; MICROENVIRONMENT; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PROSTATE CARCINOMA; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; SCID MOUSE; TUMOR GROWTH; TUMOR VASCULARIZATION;

CELL PROLIFERATION; DOWN-REGULATION; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 27744523670     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-2339-3     Document Type: Article

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