Identification of the Amino acids 300-600 of IRS-2 as 14-3-3 binding region with the importance of IGF-1/insulin-regulated phosphorylation of Ser-573

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Neukamm, Sabine S ^a,b   Toth, Rachel ^c   Morrice, Nick ^d   Campbell, David G ^c   MacKintosh, Carol ^c   Lehmann, Rainer ^a,b   Haering, Hans Ulrich ^a,b   Schleicher, Erwin D ^a,b   Weigert, Cora ^a,b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN 14 3 3; SERINE; SERINE 573; SOMATOMEDIN C; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER; MALE; MASS SPECTROMETRY; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MASS SPECTROMETRY; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION;

EID: 84865078832     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043296     Document Type: Article

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