Genome-wide screening reveals an EMT molecular network mediated by sonic hedgehog-Gli1 signaling in pancreatic cancer cells

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Xu, Xuanfu ^a   Zhou, Yingqun ^a   Xie, Chuangao ^b   Wei, Shu mei ^b   Gan, Huizhong ^c   He, Shengli ^d   Wang, Fan ^a   Xu, Ling ^a   Lu, Jie ^a   Dai, Weiqi ^a   He, Lei ^a   Chen, Ping ^a   Wang, Xingpeng ^a   Guo, Chuanyong ^a  

^a TONGJI UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ANHUI MEDICAL UNIVERSITY   (China)

^d FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALVASCULIN; COMPLEMENTARY DNA; GROWTH FACTOR; INTEGRIN; LENTIVIRUS VECTOR; MEMBRANE PROTEIN; PROTEIN KINASE B; RAS PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

AKT GENE; ANIMAL CELL; ARTICLE; CANCER CELL; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC TRANSFECTION; GENOME ANALYSIS; GLI1 GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LIVER METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PANCREAS CANCER; PI3K GENE; PROTEIN EXPRESSION; S100A4 GENE; TGF BETA GENE; TM4SF GENE; UNINDEXED SEQUENCE; WNT GENE;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENE TRANSFER TECHNIQUES; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, NUDE; ONCOGENE PROTEINS; PANCREATIC NEOPLASMS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSDUCTION, GENETIC;

EID: 84865022723     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043119     Document Type: Article

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