Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia

Leukemia and Lymphoma

Volumn 53, Issue 9, 2012, Pages 1769-1778

  Shao, Na ^a   Zou, Jie ^a   Li, Jie ^a   Chen, Feng ^a   Dai, Jianjian ^a   Qu, Xun ^a   Sun, Xiulian ^a   Ma, Daoxin ^a   Ji, Chunyan ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

apoptosis; cell cycle; HDACis; T ALL; WNT catenin signaling

Indexed keywords

ANTILEUKEMIC AGENT; BETA CATENIN; CASPASE 3; CASPASE 9; HISTONE DEACETYLASE INHIBITOR; LUCIFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P21; SUBEROYL BISHYDROXAMIC ACID; UNCLASSIFIED DRUG; VALPROIC ACID; WNT PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, LEUKEMIC; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; IMMUNOHISTOCHEMISTRY; JURKAT CELLS; POLY(ADP-RIBOSE) POLYMERASES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; VALPROIC ACID; WNT PROTEINS;

EID: 84865012869     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2012.663085     Document Type: Article

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