Target fishing and docking studies of the novel derivatives of aryl-aminopyridines with potential anticancer activity

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 17, 2012, Pages 5220-5228

  Erić, Slavica ^a   Ke, Song ^b   Barata, Teresa ^b   Solmajer, Tom ^c   Antić Stanković, Jelena ^a   Juranić, Zorica ^d   Savić, Vladimir ^a   Zloh, Mire ^b  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^d INSTITUTE FOR ONCOLOGY AND RADIOLOGY OF SERBIA   (Serbia)

Author keywords

Anticancer agents; Aryl aminopyridines; Molecular docking; Structure based drug design; Target fishing

Indexed keywords

ABELSON KINASE; ANTINEOPLASTIC AGENT; ARYL AMINOPYRIDINE DERIVATIVE; AURORA A KINASE; CYCLIN DEPENDENT KINASE 2; DNA TOPOISOMERASE; NEUTROPHIL COLLAGENASE; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CYCLE REGULATION; COMPUTER MODEL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; IC 50; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION; VIRTUAL REALITY;

AMINOPYRIDINES; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84864987097     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.06.051     Document Type: Article

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