Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2245-2248

  Byth, Kate F ^a   Culshaw, Janet D ^a   Green, Stephen ^a   Oakes, Sandra E ^a   Thomas, Andrew P ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

CDK2 inhibitor

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; PYRIDINE DERIVATIVE;

ARTICLE; CHEMICAL MODIFICATION; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; PHYSICAL CHEMISTRY; REACTION OPTIMIZATION; STRUCTURE ACTIVITY RELATION;

CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1842639592     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.015     Document Type: Article

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