Baicalein potently inhibits Rho kinase activity and suppresses actin stress fiber formation in angiotensin II-stimulated H9c2 cells

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 8, 2012, Pages 1281-1286

  Oh, Kwang Seok ^a   Oh, Byung Koo ^a   Park, Cheon Ho ^a   Mun, Jihye ^a   Won, Suk Hyun ^a   Lee, Byung Ho ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Actin stress fiber; Angiotensin II; Baicalein; H9c2 cell; Rho kinase

Indexed keywords

ANGIOTENSIN II; BAICALEIN; MYOSIN LIGHT CHAIN; MYOSIN PHOSPHATASE; PHOSPHATASE; RHO KINASE; UNCLASSIFIED DRUG;

ACTIN STRESS FIBER; ANIMAL CELL; ANTIFIBROTIC EFFECT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MUSCLE CELL; IC 50; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; STRESS FIBER;

ACTINS; ANGIOTENSIN II; ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROSIS; FLAVANONES; INHIBITORY CONCENTRATION 50; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RHO-ASSOCIATED KINASES; SCUTELLARIA BAICALENSIS; STRESS FIBERS; VASOCONSTRICTOR AGENTS;

EID: 84864958000     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00121     Document Type: Article

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