Cholinergic blockade under working memory demands encountered by increased rehearsal strategies: Evidence from fMRI in healthy subjects

European Archives of Psychiatry and Clinical Neuroscience

Volumn 262, Issue 4, 2012, Pages 329-339

  Voss, Bianca ^a,b   Thienel, Renate ^c   Reske, Martina ^b,d   Kellermann, Thilo ^a,b   Sheldrick, Abigail J ^a,b   Halfter, Sarah ^a,b   Radenbach, Katrin ^e   Shah, Nadim J ^b,d,f   Habel, Ute ^a,b   Kircher, Tilo T J ^g  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b JARA TRANSLATIONAL BRAIN MEDICINE   (Germany)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d FORSCHUNGSZENTRUM JÜLICH   (Germany)

^e UNIVERSITY OF GÖTTINGEN   (Germany)

^f UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^g PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Cholinergic system; FMRI; Muscarinic antagonist; N back task; Scopolamine; Working memory

Indexed keywords

ACETYLCHOLINE; MUSCARINIC RECEPTOR;

ADULT; ARTICLE; BRAIN MAPPING; CEREBELLUM; CHOLINERGIC RECEPTOR BLOCKING; CHOLINERGIC SYSTEM; CHOLINERGIC TRANSMISSION; DOWN REGULATION; EXECUTIVE FUNCTION; FRONTAL LOBE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; IMAGE ANALYSIS; LEARNING; MALE; NORMAL HUMAN; OCCIPITAL LOBE; PARIETAL LOBE; PERFORMANCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; WORKING MEMORY;

ADULT; DOWN-REGULATION; EXECUTIVE FUNCTION; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY, SHORT-TERM; MUSCARINIC ANTAGONISTS; NEUROPSYCHOLOGICAL TESTS; PREFRONTAL CORTEX; REACTION TIME; RECEPTORS, MUSCARINIC; SCOPOLAMINE HYDROBROMIDE; SINGLE-BLIND METHOD; SYNAPTIC TRANSMISSION;

EID: 84864917303     PISSN: 09401334     EISSN: 14338491     Source Type: Journal    
DOI: 10.1007/s00406-011-0267-6     Document Type: Article

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