Cholinergic enhancement eliminates modulation of neural activity by task difficulty in the prefrontal cortex during working memory

Journal of Cognitive Neuroscience

Volumn 20, Issue 7, 2008, Pages 1342-1353

  Furey, Maura L ^a,e   Ricciardi, Emiliano ^b,c   Schapiro, Mark B ^d   Rapoport, Stanley I ^a   Pietrini, Pietro ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF PISA   (Italy)

^c SCUOLA SUPERIORE SANT ANNA   (Italy)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHYSOSTIGMINE; SODIUM CHLORIDE;

ADULT; ARTICLE; BLOOD FLOW; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; VISION; WORKING MEMORY;

ACETYLCHOLINE; ADULT; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; CHOLINESTERASE INHIBITORS; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; PHYSOSTIGMINE; POSITRON-EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; REACTION TIME; TIME FACTORS;

EID: 45849132019     PISSN: 0898929X     EISSN: 15308898     Source Type: Journal    
DOI: 10.1162/jocn.2008.20092     Document Type: Article

References (41)

1. Baddeley, A. (2003). Working memory and language: An overview. Journal of Communication Disorders, 36, 189-208.
2. Baddeley, A., Logie, R., Bressi, S., Della Sala, S., & Spinnler, H. (1986). Dementia and working memory. Quarterly Journal of Experimental Psychology A, 38, 603-618.
3. Barch, D. M., Braver, T. S., Nystrom, L. E., Forman, S. D., Noll, D. C., & Cohen, J. D. (1997). Dissociating working memory from task difficulty in human prefrontal cortex. Neuropsychologia, 35, 1373-1380.
4. Bentley, P., Husain, M., & Dolan, R. J. (2004). Effects of cholinergic enhancement on visual stimulation, spatial attention, and spatial working memory. Neuron, 41, 969-982.
5. Bentley, P., Vuilleumier, P., Thiel, C. M., Driver, J., & Dolan, R. J. (2003a). Cholinergic enhancement modulates neural correlates of selective attention and emotional processing. Neuroimage, 20, 58-70.
6. Bentley, P., Vuilleumier, P., Thiel, C. M., Driver, J., & Dolan, R. J. (2003b). Effects of attention and emotion on repetition priming and their modulation by cholinergic enhancement. Journal of Neurophysiology, 90, 1171-1181.
7. Braver, T. S., Cohen, J. D., Nystrom, L. E., Jonides, J., Smith, E. E., & Noll, D. C. (1997). A parametric study of prefrontal cortex involvement in human working memory. Neuroimage, 5, 49-62.
8. Bullmore, E., Suckling, J., Zelaya, F., Long, C., Honey, G., Reed, L., et al. (2003). Practice and difficulty evoke anatomically and pharmacologically dissociable brain activation dynamics. Cerebral Cortex, 13, 144-154.
9. D'Esposito, M., Postle, B. R., Ballard, D., & Lease, J. (1999). Maintenance versus manipulation of information held in working memory: An event-related fMRI study. Brain and Cognition, 41, 66-86.
10. D'Esposito, M., Postle, B. R., & Rypma, B. (2000). Prefrontal cortical contributions to working memory: Evidence from event-related fMRI studies. Experimental Brain Research, 133, 3-11.
11. Dawson, G. R., & Iversen, S. D. (1993). The effects of novel cholinesterase inhibitors and selective muscarinic receptor agonists in tests of reference and working memory. Behavioural Brain Research, 57, 143-153.
12. Everitt, B. J., & Robbins, T. W. (1997). Central cholinergic systems and cognition. Annual Review of Psychology, 48, 649-684.
13. Freo, U., Ricciardi, E., Pietrini, P., Schapiro, M. B., Rapoport, S. I., & Furey, M. L. (2005). Pharmacological modulation of prefrontal cortical activity during a working memory task in young and older humans: A PET study with physostigmine. American Journal of Psychiatry, 162, 2061-2070.
14. Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J.-B., Frith, C. D., & Frackowiak, R. S. J. (1995). Statistical parametric maps in functional imaging: A general linear approach. Human Brain Mapping, 2, 189-210.
15. Furey, M. L., Pietrini, P., Alexander, G. E., Mentis, M. J., Szczepanik, J., Shetty, U., et al. (2000). Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans. Pharmacology, Biochemistry and Behavior, 66, 475-481.
16. Furey, M. L., Pietrini, P., Alexander, G. E., Schapiro, M. B., & Horwitz, B. (2000). Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: A positron emission tomography regional cerebral blood f low study in healthy humans. Brain Research Bulletin, 51, 213-218.
17. Furey, M. L., Pietrini, P., & Haxby, J. V. (2000). Cholinergic enhancement and increased selectivity of perceptual processing during working memory. Science, 290, 2315-2319.
18. Furey, M. L., Pietrini, P., Haxby, J. V., Alexander, G. E., Lee, H. C., VanMeter, J., et al. (1997). Cholinergic stimulation alters performance and task-specific regional cerebral blood f low during working memory. Proceedings of the National Academy of Sciences, U.S.A., 94, 6512-6516.
19. Furey, M. L., Pietrini, P., Haxby, J. V., & Drevets, W. C. (2007). Selective effects of cholinergic modulation on task performance during selective attention. Neuropsychopharmacology, 33, 913-923.
20. Glasky, A. J., Melchior, C. L., Pirzadeh, B., Heydari, N., & Ritzmann, R. F. (1994). Effect of AIT-082, a purine analog, on working memory in normal and aged mice. Pharmacology, Biochemistry and Behavior, 47, 325-329.
21. Grady, C. L., Horwitz, B., Pietrini, P., Mentis, M. J., Ungerleider, L. G., Rapoport, S. I., et al. (1996). Effect of task difficulty on cerebral blood f low during perceptual matching of faces. Human Brain Mapping, 4, 227-239.
22. Grady, C. L., McIntosh, A. R., Bookstein, F., Horwitz, B., Rapoport, S. I., & Haxby, J. V. (1998). Age-related changes in regional cerebral blood f low during working memory for faces. Neuroimage, 8, 409-425.
23. Hasselmo, M. E. (1995). Neuromodulation and cortical function: Modeling the physiological basis of behavior. Behavioural Brain Research, 67, 1-27.
24. Haxby, J. V., Ungerleider, L. G., Horwitz, B., Rapoport, S. I., & Grady, C. L. (1995). Hemispheric differences in neural systems for face working memory: A PET-rCBF study. Human Brain Mapping, 3, 68-82.
25. Kumari, V., Aasen, I., Ffytche, D., Williams, S. C., & Sharma, T. (2006). Neural correlates of adjunctive rivastigmine treatment to antipsychotics in schizophrenia: A randomized, placebo-controlled, double-blind fMRI study. Neuroimage, 29, 545-556.
26. Mesulam, M. M. (1995). Cholinergic pathways and the ascending reticular activating system of the human brain. Annals of the New York Academy of Sciences, 757, 169-179.
27. Murphy, P. C., & Sillito, A. M. (1991). Cholinergic enhancement of direction selectivity in the visual cortex of the cat. Neuroscience, 40, 13-20.
28. Oduro, K. A. (1975). Glycopyrrolate methobromide: 2. Comparison with atropine sulphate in anaesthesia. Canadian Anaesthetists' Society Journal, 22, 466-473.
29. Robbins, T. W. (1997). Arousal systems and attentional processes. Biological Psychology, 45, 57-71.
30. Rombouts, S. A., Barkhof, F., Van Meel, C. S., & Scheltens, P. (2002). Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry, 73, 665-671.
31. Rusted, J. M., & Warburton, D. M. (1988). The effects of scopolamine on working memory in healthy young volunteers. Psychopharmacology (Berlin), 96, 145-152.
32. Rypma, B., Berger, J. S., Genova, H. M., Rebbechi, D., & D'Esposito, M. (2005). Dissociating age-related changes in cognitive strategy and neural efficiency using event-related fMRI. Cortex, 41, 582-594.
33. Rypma, B., Berger, J. S., Prabhakaran, V., Bly, B. M., Kimberg, D. Y., Biswal, B. B., et al. (2006). Neural correlates of cognitive efficiency. Neuroimage, 33, 969-979.
34. Sarter, M., & Bruno, J. P. (2000). Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: Differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents. Neuroscience, 95, 933-952.
35. Sarter, M., Nelson, C. L., & Bruno, J. P. (2005). Cortical cholinergic transmission and cortical information processing in schizophrenia. Schizophrenia Bulletin, 31, 117-138.
36. Sato, H., Hata, Y., Masui, H., & Tsumoto, T. (1987). A functional role of cholinergic innervation to neurons in the cat visual cortex. Journal of Neurophysiology, 58, 765-780.
37. Sayala, S., Sala, J. B., & Courtney, S. M. (2006). Increased neural efficiency with repeated performance of a working memory task is information-type dependent. Cerebral Cortex, 16, 609-617.
38. Schumacher, E. H., Cole, M. W., & D'Esposito, M. (2007). Selection and maintenance of stimulus-response rules during preparation and performance of a spatial choice-reaction task. Brain Research, 1136, 77-87.
39. Sillito, A. M., & Kemp, J. A. (1983). Cholinergic modulation of the functional organization of the cat visual cortex. Brain Research, 289, 143-155.
40. Talairach, J., & Tournoux, P. (1988). Co-planar stereotaxic atlas of the human brain. New York: Thieme.
41. Terry, A. V., Jr., Jackson, W. J., & Buccafusco, J. J. (1993). Effects of concomitant cholinergic and adrenergic stimulation on learning and memory performance by young and aged monkeys. Cerebral Cortex, 3, 304-312.