Specific impairments in visuospatial working and short-term memory following low-dose scopolamine challenge in healthy older adults

Neuropsychologia

Volumn 46, Issue 10, 2008, Pages 2476-2484

  Thomas, Elizabeth ^a   Snyder, Peter J ^b,c   Pietrzak, Robert H ^d,e   Jackson, Colleen E ^f   Bednar, Martin ^g   Maruff, Paul ^a,e  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b BROWN UNIVERSITY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e University of Connecticut ^*  (Australia)

^f UNIVERSITY OF CONNECTICUT   (United States)

^g PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Donepezil cognitive function; Scopolamine; Spatial working memory

Indexed keywords

DONEPEZIL; SCOPOLAMINE;

AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG MECHANISM; FEMALE; HUMAN; LOW DRUG DOSE; MALE; MAXIMUM PLASMA CONCENTRATION; MAZE TEST; MEMORY DISORDER; RANDOMIZED CONTROLLED TRIAL; SHORT TERM MEMORY; SINGLE DRUG DOSE; SPATIAL MEMORY; VISUOMOTOR COORDINATION; WORKING MEMORY;

AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; GERIATRIC ASSESSMENT; HUMANS; INDANS; LINEAR MODELS; MALE; MAZE LEARNING; MEMORY DISORDERS; MEMORY, SHORT-TERM; PIPERIDINES; SCOPOLAMINE; SPATIAL BEHAVIOR;

EID: 44649130626     PISSN: 00283932     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2008.04.010     Document Type: Article

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