PCB153 disrupts thyroid hormone homeostasis by affecting its biosynthesis, biotransformation, feedback regulation, and metabolism

Hormone and Metabolic Research

Volumn 44, Issue 9, 2012, Pages 662-669

  Liu, C ^a   Wang, C ^a   Yan, M ^a   Quan, C ^a   Zhou, J ^a   Yang, K ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

deiodinases; hepatic enzymes; PCB153; synthesis associated proteins

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; CYTOCHROME P450 2B1; CYTOCHROME P450 3A1; LIOTHYRONINE; LIVER ENZYME; MESSENGER RNA; PROTIRELIN; PROTIRELIN RECEPTOR; SODIUM IODIDE SYMPORTER; THYROGLOBULIN; THYROID HORMONE; THYROID PEROXIDASE; THYROTROPIN; THYROTROPIN RECEPTOR; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEEDBACK SYSTEM; HOMEOSTASIS; HORMONE TRANSPORT; LIOTHYRONINE BLOOD LEVEL; LIVER WEIGHT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROGLOBULIN BLOOD LEVEL; THYROID HORMONE METABOLISM; THYROID HORMONE SYNTHESIS; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; WEIGHT CHANGE;

ANIMALS; BIOTRANSFORMATION; ENDOCRINE DISRUPTORS; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION; HOMEOSTASIS; HUMANS; MALE; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, THYROTROPIN; THYROID HORMONES;

ANIMALIA; RATTUS;

EID: 84864864582     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0032-1311569     Document Type: Article

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