Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs

Vaccine

Volumn 30, Issue 40, 2012, Pages 5830-5838

  Loving, Crystal L ^a   Vincent, Amy L ^a   Pena, Lindomar ^b,c   Perez, Daniel R ^b,c  

^a NATIONAL ANIMAL DISEASE CENTER   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

Adaptive immune response; Influenza; Pigs; Vaccine

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INACTIVATED VACCINE; INFLUENZA VACCINE;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COMPARATIVE STUDY; DNA MODIFICATION; EXPERIMENTAL PIG; GENETIC REASSORTMENT; HEMAGGLUTINATION INHIBITION; IMMUNOGLOBULIN BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA VACCINATION; INFLUENZA VIRUS A H1N1; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MEMORY T LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; SERUM; STRUCTURAL GENE; TEMPERATURE SENSITIVITY; VIRUS INACTIVATION; VIRUS NEUTRALIZATION; VIRUS VIRULENCE;

ADAPTIVE IMMUNITY; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; ANTIBODY FORMATION; HEMAGGLUTINATION INHIBITION TESTS; IMMUNITY, CELLULAR; IMMUNOLOGIC MEMORY; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; INTERFERON-GAMMA; LUNG; NEUTRALIZATION TESTS; ORTHOMYXOVIRIDAE INFECTIONS; SWINE; T-LYMPHOCYTES; VACCINES, ATTENUATED; VACCINES, INACTIVATED;

EID: 84864826521     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.07.033     Document Type: Article

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