Modifications in the polymerase genes of a swine-like triple-reassortant influenza virus to generate live attenuated vaccines against 2009 pandemic H1N1 viruses

Journal of Virology

Volumn 85, Issue 1, 2011, Pages 456-469

  Pena, Lindomar ^a,b   Vincent, Amy L ^c   Ye, Jianqiang ^a,b   Ciacci Zanella, Janice R ^c,e   Angel, Matthew ^a,b   Lorusso, Alessio ^c   Gauger, Philip C ^c   Janke, Bruce H ^d   Loving, Crystal L ^c   Perez, Daniel R ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^c NATIONAL ANIMAL DISEASE CENTER   (United States)

^d IOWA STATE UNIVERSITY   (United States)

^e EMBRAPA CERRADOS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; LIVE ATTENUATED INFLUENZA VACCINE; LIVE VACCINE; RNA POLYMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA MODIFICATION; DRUG EFFICACY; DRUG SAFETY; ENZYME ACTIVITY; FEMALE; GENETIC REASSORTMENT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNIZATION; IN VIVO STUDY; INFLUENZA A (H1N1); INFLUENZA VACCINATION; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; LETHALITY; MOUSE; NONHUMAN; PANDEMIC INFLUENZA; PRIORITY JOURNAL; RESPIRATORY SYSTEM; SWINE; TEMPERATURE; VIROGENESIS; VIRUS ATTENUATION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALIA; AVES; GALLUS GALLUS; INFLUENZA A VIRUS; MUS; ORTHOMYXOVIRIDAE; SUIDAE;

EID: 78650051252     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01503-10     Document Type: Article

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