Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection

Virology Journal

Volumn 5, Issue , 2008, Pages

  DiNapoli, Joshua M ^a   Murphy, Brian R ^a   Collins, Peter L ^a   Bukreyev, Alexander ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; INFECTION; INFLUENZA VIRUS; INTERFERON PRODUCTION; LUNG INFECTION; MOUSE; NONHUMAN; NOSE INFECTION; REINFECTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SECONDARY INFECTION; SKIN INFECTION; SPLEEN; TISSUE DISTRIBUTION; VACCINIA VIRUS; VIRUS IMMUNITY; VIRUS INFECTIVITY; VIRUS TYPING; ANIMAL; ANTIBODY SPECIFICITY; CELL CULTURE; CELL LINE; CYTOTOXIC T LYMPHOCYTE; DISEASE TRANSMISSION; HUMAN; IMMUNOLOGY; LUNG; ORTHOMYXOVIRUS; VIROLOGY; VIRUS INFECTION;

HUMAN RESPIRATORY SYNCYTIAL VIRUS; MUS; ORTHOMYXOVIRIDAE; RICE STRIPE VIRUS; VACCINIA VIRUS;

ANIMALS; ANTIGENS, VIRAL; CELL LINE; CELLS, CULTURED; HUMANS; INTERFERON TYPE II; LUNG; MICE; ORGAN SPECIFICITY; ORTHOMYXOVIRIDAE; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RESPIRATORY SYNCYTIAL VIRUSES; T-LYMPHOCYTES, CYTOTOXIC; VACCINIA VIRUS;

EID: 53249086182     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-5-105     Document Type: Article

References (25)

1. Respiratory syncytial virus infection suppresses lung CD8+ T-cell effector activity and peripheral CD8+ T-cell memory in the respiratory tract. J Chang TJ Braciale, Nat Med 2002 8 54 60 10.1038/nm0102-54 11786907
2. Respiratory syncytial virus (RSV) F, G, M2 (22 K), and N proteins each induce resistance to RSV challenge, but resistance induced by M2 and N proteins is relatively short-lived. M Connors PL Collins CY Firestone BR Murphy, J Virol 1991 65 1634 1637 1995956
3. Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract. PM Gray S Arimilli EM Palmer GD Parks MA Alexander-Miller, J Virol 2005 79 3339 3349 15731228 10.1128/JVI.79.6.3339-3349.2005
4. Functional impairment of cytotoxic T cells in the lung airways following respiratory virus infections. S Vallbracht H Unsold S Ehl, Eur J Immunol 2006 36 1434 1442 10.1002/eji.200535642 16708402
5. Activation and inactivation of antiviral CD8 T cell responses during murine pneumovirus infection. EA Claassen PA van der Kant ZS Rychnavska GM van Bleek AJ Easton RG van der Most, J Immunol 2005 175 6597 6604 16272314
6. Comparison of the virulence of wild-type thymidine kinase (tk)-deficient and tk+ phenotypes of vaccinia virus recombinants after intranasal inoculation of mice. G Taylor EJ Stott G Wertz A Ball, J Gen Virol 1991 72 Pt 1 125 130 10.1099/0022-1317-72-1-125 1990060
7. Respiratory infection of mice with vaccinia virus. GS Turner, J Gen Virol 1967 1 399 402 10.1099/0022-1317-1-3-399 6082340
8. A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. PC Reading GL Smith, J Gen Virol 2003 84 1973 1983 10.1099/vir.0.19285-0 12867627
9. Dynamic programming of CD8+ T cell trafficking after live viral immunization. L Liu RC Fuhlbrigge K Karibian T Tian TS Kupper, Immunity 2006 25 511 520 10.1016/j.immuni.2006.06.019 16973385
10. Cytotoxic T cells specific for a single peptide on the M2 protein of respiratory syncytial virus are the sole mediators of resistance induced by immunization with M2 encoded by a recombinant vaccinia virus. AB Kulkarni PL Collins I Bacik JW Yewdell JR Bennink JE Crowe Jr BR Murphy, J Virol 1995 69 1261 1264 7815502
11. Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype. RM Buller GL Smith K Cremer AL Notkins B Moss, Nature 1985 317 813 815 10.1038/317813a0 4058585
12. Biological characterization of recombinant vaccinia viruses in mice infected by the respiratory route. JD Williamson RW Reith LJ Jeffrey JR Arrand M Mackett, J Gen Virol 1990 71 Pt 11 2761 2767 10.1099/0022-1317-71-11-2761 2254756
13. Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells. PM Taylor J Davey K Howland JB Rothbard BA Askonas, Immunogenetics 1987 26 267 272 10.1007/BF00346521 2443447
14. Granulocyte-macrophage colony-stimulating factor expressed by recombinant respiratory syncytial virus attenuates viral replication and increases the level of pulmonary antigen-presenting cells. A Bukreyev IM Belyakov JA Berzofsky BR Murphy PL Collins, J Virol 2001 75 12128 12140 11711604 10.1128/JVI.75.24. 12128-12140.2001
15. Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus. A Bukreyev IM Belyakov GA Prince KC Yim KK Harris JA Berzofsky PL Collins, J Virol 2005 79 9515 9526 16014914 10.1128/JVI.79.15.9515- 9526.2005
16. Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. S Lee SA Miller DW Wright MT Rock JE Crowe Jr, J Virol 2007 81 2349 2358 17182672 10.1128/JVI.01910-06
17. Regulation of Cytokine Production by Virus-specific CD8 T Cells in the Lung. RB Fulton MR Olson SM Varga, J Virol 2008 18524828
18. Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus. MJ Cannon PJ Openshaw BA Askonas, J Exp Med 1988 168 1163 1168 3262705 10.1084/jem.168.3.1163
19. Structural and functional consequences of alveolar cell recognition by CD8(+) T lymphocytes in experimental lung disease. RI Enelow AZ Mohammed MH Stoler AN Liu JS Young YH Lou TJ Braciale, J Clin Invest 1998 102 1653 1661 9802879 10.1172/JCI4174
20. A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease. RI Enelow MH Stoler A Srikiatkhachorn C Kerlakian S Agersborg JA Whitsett TJ Braciale, J Clin Invest 1996 98 914 922 8770862 10.1172/JCI118874
21. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice. BS Graham LA Bunton PF Wright DT Karzon, J Clin Invest 1991 88 1026 1033 1909350 10.1172/JCI115362
22. Restoring function in exhausted CD8 T cells during chronic viral infection. DL Barber EJ Wherry D Masopust B Zhu JP Allison AH Sharpe GJ Freeman R Ahmed, Nature 2006 439 682 687 10.1038/nature04444 16382236
23. Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization. BR Murphy AV Sotnikov LA Lawrence SM Banks GA Prince, Vaccine 1990 8 497 502 10.1016/0264-410X(90)90253-I 2251875
24. Analysis of the local and systemic immune responses induced in BALB/c mice by experimental respiratory syncytial virus infection. JJ Anderson J Norden D Saunders GL Toms R Scott, J Gen Virol 1990 71 Pt 7 1561 1570 10.1099/0022-1317-71-7-1561 2197371
25. The cytolytic activity of pulmonary CD8+ lymphocytes, induced by infection with a vaccinia virus recombinant expressing the M2 protein of respiratory syncytial virus (RSV), correlates with resistance to RSV infection in mice. AB Kulkarni M Connors CY Firestone HC Morse 3rd BR Murphy, J Virol 1993 67 1044 1049 8419638