Alkylphenols from the roots of Ardisia brevicaulis induce G1 arrest and apoptosis through endoplasmic reticulum stress pathway in human non-small-cell lung cancer cells

Chemical and Pharmaceutical Bulletin

Volumn 60, Issue 8, 2012, Pages 1029-1036

  Zhu, Guo Yuan ^a   Wong, Blenda Chi Kwan ^a   Lu, Aiping ^a   Bian, Zhao Xiang ^a   Zhang, Ge ^b   Chen, Hu Biao ^a   Wong, Yuen Fan ^a   Fong, Wang Fun ^a   Yang, Zhijun ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Alkylphenol; Ardisia brevicaulis; Endoplasmic reticulum stress; Human non small cell lung cancer; Myrsinaceae

Indexed keywords

ALKYLPHENOL; ANTINEOPLASTIC AGENT; ARDISIPHENOL E; ARDISIPHENOL F; BIM PROTEIN; BINDING IMMUNOGLOBULIN PROTEIN; BINDING PROTEIN; CASPASE 3; CASPASE 9; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYBRID PROTEIN; INOSITOL; INOSITOL REQUIRING ENZYME 1; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P27; S PHASE KINASE ASSOCIATED PROTEIN 2; UBIQUITIN FUSION DEGRADATION PROTEIN 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARDISIA; ARDISIA BREVICAULIS; ARTICLE; CANCER CELL; CELL CYCLE S PHASE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PLANT ROOT; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UPREGULATION;

APOPTOSIS; ARDISIA; BASE SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DNA PRIMERS; ENDOPLASMIC RETICULUM; G1 PHASE; HUMANS; LUNG NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE STRESS; PHENOLS; PLANT ROOTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84864739694     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c12-00302     Document Type: Article

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