Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts

Developmental Dynamics

Volumn 240, Issue 6, 2011, Pages 1493-1501

  Paul, Binu M ^a   Vassmer, Dianne ^a   Taylor, Aaron ^a   Magenheimer, Lynn ^a   Carlton, Carol G ^a   Piontek, Klaus B ^b   Germino, Gregory G ^c   Vanden Heuvel, Gregory B ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Apoptosis, p27; Cux1; Polycystic kidney disease

Indexed keywords

CREATINE KINASE; CUX1 PROTEIN; POLYCYSTIN 1; PROTEIN P21; PROTEIN P27; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATIONAL STUDY; CYST (RESTING STAGE); DISEASE COURSE; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; EPITHELIUM CELL; GENE DELETION; KIDNEY COLLECTING TUBULE; KIDNEY DEVELOPMENT; LETHALITY; MOUSE; NEWBORN; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DISEASE PROGRESSION; DOWN-REGULATION; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HOMEODOMAIN PROTEINS; KIDNEY DISEASES, CYSTIC; KIDNEY TUBULES, COLLECTING; MALE; MICE; MICE, TRANSGENIC; NUCLEAR PROTEINS; REPRESSOR PROTEINS; TRANSFECTION; TRPP CATION CHANNELS; UP-REGULATION;

MUS;

EID: 79955720081     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22625     Document Type: Article

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