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Volumn 20, Issue 3, 2012, Pages 295-305

Mechanisms of action of systemic antibiotics used in periodontal treatment and mechanisms of bacterial resistance to these drugs

Author keywords

Antibiotics; Dru resistance; Infectiou diseases; Periodonta diseases

Indexed keywords

ANTIINFECTIVE AGENT; MACROLIDE; METRONIDAZOLE;

EID: 84864685407     PISSN: 16787757     EISSN: 16787765     Source Type: Journal    
DOI: 10.1590/S1678-77572012000300002     Document Type: Review
Times cited : (153)

References (172)
  • 1
    • 0023789332 scopus 로고
    • Hybridization analysis of the class P tetracycline resistance determinant from the Clostridium perfrigens R-plasmid, pCW3
    • Abraham LJ, Berryman DI, Rood JI. Hybridization analysis of the class P tetracycline resistance determinant from the Clostridium perfrigens R-plasmid, pCW3. Plasmid. 1988;19:113-20.
    • (1988) Plasmid. , vol.19 , pp. 113-120
    • Abraham, L.J.1    Berryman, D.I.2    Rood, J.I.3
  • 2
    • 0026147518 scopus 로고
    • Amoxicillin with clavulanic acid and tetracycline in periodontal therapy
    • Abu-Fanas SH, Drucker DB, Hull PS. Amoxicillin with clavulanic acid and tetracycline in periodontal therapy. J Dent. 1991;19:97-9.
    • (1991) J Dent. , vol.19 , pp. 97-99
    • Abu-Fanas, S.H.1    Drucker, D.B.2    Hull, P.S.3
  • 3
    • 0026109941 scopus 로고
    • Identification and susceptibility to seven antimicrobial agents, of 61 gram-negative anaerobic rods from periodontal pockets
    • Abu-Fanas SH, Drucker DB, Hull PS, Reeder JC, Ganguli LA. Identification and susceptibility to seven antimicrobial agents, of 61 gram-negative anaerobic rods from periodontal pockets. J Dent. 1991;19:46-50.
    • (1991) J Dent. , vol.19 , pp. 46-50
    • Abu-Fanas, S.H.1    Drucker, D.B.2    Hull, P.S.3    Reeder, J.C.4    Ganguli, L.A.5
  • 4
    • 0031725109 scopus 로고    scopus 로고
    • Antimicrobial susceptibilities of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens spp. isolated in Spain
    • Andrés MT, Chung WO, Roberts MC, Fierro JF. Antimicrobial susceptibilities of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens spp. isolated in Spain. Antimicrob Agents Chemother. 1998;42:3022-3.
    • (1998) Antimicrob Agents Chemother. , vol.42 , pp. 3022-3023
    • Andrés, M.T.1    Chung, W.O.2    Roberts, M.C.3    Fierro, J.F.4
  • 5
    • 77954852286 scopus 로고    scopus 로고
    • Antibiotic resistance of subgingival species in chronic periodontitis patients
    • Ardila CM, Granada MI, Guzmán IC. Antibiotic resistance of subgingival species in chronic periodontitis patients. J Periodont Res. 2010;45:557-63.
    • (2010) J Periodont Res. , vol.45 , pp. 557-563
    • Ardila, C.M.1    Granada, M.I.2    Guzmán, I.C.3
  • 6
    • 77953220795 scopus 로고    scopus 로고
    • Comparison of the microbiological features of chronic and aggressive periodontitis
    • Armitage GC. Comparison of the microbiological features of chronic and aggressive periodontitis. Periodontol 2000. 2010;53:70-88.
    • (2010) Periodontol 2000. , vol.53 , pp. 70-88
    • Armitage, G.C.1
  • 7
    • 0032815928 scopus 로고    scopus 로고
    • Emergence of mefA and mefE genes in β-haemolytic streptococci and pneumococci in France
    • Arpin C, Canron MH, Noury P, Quentin C. Emergence of mefA and mefE genes in β-haemolytic streptococci and pneumococci in France. J Antimicrob Chemother. 1999;44:133-4.
    • (1999) J Antimicrob Chemother. , vol.44 , pp. 133-134
    • Arpin, C.1    Canron, M.H.2    Noury, P.3    Quentin, C.4
  • 8
    • 0016746179 scopus 로고
    • Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline and oxytetracycline in dogs
    • Barza M, Brown RB, Shanks C, Gamble C, Weinstein L. Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline and oxytetracycline in dogs. Antimicrob Agents Chemother. 1975;8:713-20.
    • (1975) Antimicrob Agents Chemother. , vol.8 , pp. 713-720
    • Barza, M.1    Brown, R.B.2    Shanks, C.3    Gamble, C.4    Weinstein, L.5
  • 10
    • 79958745037 scopus 로고    scopus 로고
    • Comparison of the effect of a single dose of erythromycin with pantoprazole on gastric content volume and acidity in elective general surgery patients
    • Bhatia N, Palta S, Arora K. Comparison of the effect of a single dose of erythromycin with pantoprazole on gastric content volume and acidity in elective general surgery patients. J Anaesthesiol Clin Pharmacol. 2011;27:195-8.
    • (2011) J Anaesthesiol Clin Pharmacol. , vol.27 , pp. 195-198
    • Bhatia, N.1    Palta, S.2    Arora, K.3
  • 12
    • 0032875787 scopus 로고    scopus 로고
    • Periodontal tissue disposition of azithromycin in patients affected by chronic inflammatory periodontal diseases
    • Blandizzi C, Malizia T, Lupetti A, Pesce D, Gabriele M, Giuca MR, et al. Periodontal tissue disposition of azithromycin in patients affected by chronic inflammatory periodontal diseases. J Periodontol. 1999;70:960-6.
    • (1999) J Periodontol. , vol.70 , pp. 960-966
    • Blandizzi, C.1    Malizia, T.2    Lupetti, A.3    Pesce, D.4    Gabriele, M.5    Giuca, M.R.6    et al7
  • 13
    • 0025774974 scopus 로고
    • Purification and characterization of Tet(M), a protein that renders ribosomes resistant to tetracycline
    • Burdett V. Purification and characterization of Tet(M), a protein that renders ribosomes resistant to tetracycline. J Biol Chem. 1991;266:2872-7.
    • (1991) J Biol Chem. , vol.266 , pp. 2872-2877
    • Burdett, V.1
  • 14
    • 0022544304 scopus 로고
    • Streptococcal tetracycline resistance mediated at the level of protein synthesis
    • Burdett V. Streptococcal tetracycline resistance mediated at the level of protein synthesis. J Bacteriol. 1986;165:564-9.
    • (1986) J Bacteriol. , vol.165 , pp. 564-569
    • Burdett, V.1
  • 15
    • 0041833332 scopus 로고    scopus 로고
    • Mobile genes coding for efflux-mediated antimicrobial resistance in Gram-positive and Gram-negative bacteria
    • Butaye P, Cloeckaert A, Schwarz S. Mobile genes coding for efflux-mediated antimicrobial resistance in Gram-positive and Gram-negative bacteria. Int J Antimicrob Agents. 2003;22:205-10.
    • (2003) Int J Antimicrob Agents. , vol.22 , pp. 205-210
    • Butaye, P.1    Cloeckaert, A.2    Schwarz, S.3
  • 16
    • 17644401680 scopus 로고    scopus 로고
    • Scaling and root planing, systemic metronidazole and professional plaque removal in the treatment of chronic periodontitis in a Brazilian population. II. microbiological results
    • Carvalho LH, D'Avila GB, Leão A, Goncalves C, Haffajee AD, Socransky SS, et al. Scaling and root planing, systemic metronidazole and professional plaque removal in the treatment of chronic periodontitis in a Brazilian population. II. microbiological results. J Clin Periodontol. 2005;32:406-11.
    • (2005) J Clin Periodontol. , vol.32 , pp. 406-411
    • Carvalho, L.H.1    D'Avila, G.B.2    Leão, A.3    Goncalves, C.4    Haffajee, A.D.5    Socransky, S.S.6    et al7
  • 17
    • 10444256588 scopus 로고    scopus 로고
    • Scaling and root planing, systemic metronidazole and professional plaque removal in the treatment of chronic periodontitis in a Brazilian population. I. clinical results
    • Carvallho LH, D'Avila GB, Leão A, Haffajee AD, Socransky SS, Feres M. Scaling and root planing, systemic metronidazole and professional plaque removal in the treatment of chronic periodontitis in a Brazilian population. I. clinical results. J Clin Periodontol. 2004;31:1017-76.
    • (2004) J Clin Periodontol. , vol.31 , pp. 1017-1076
    • Carvallho, L.H.1    D'Avila, G.B.2    Leão, A.3    Haffajee, A.D.4    Socransky, S.S.5    Feres, M.6
  • 18
    • 0003126476 scopus 로고    scopus 로고
    • Antimicrobial agents. General considerations
    • In: Gilman AG, Rall TW, Nies AS, Taylor P., New York: Pergamon Press
    • Chambers HF, Sande MA. Antimicrobial agents. General considerations. In: Gilman AG, Rall TW, Nies AS, Taylor P. The pharmacological basis of therapeutics. New York: Pergamon Press; 1996. p. 1026-9.
    • (1996) The pharmacological basis of therapeutics , pp. 1026-1029
    • Chambers, H.F.1    Sande, M.A.2
  • 19
    • 0037477425 scopus 로고    scopus 로고
    • Antibiotic resistance of pathogenic bacteria from odontogenic infections in Taiwan
    • Chan Y, Chan CH. Antibiotic resistance of pathogenic bacteria from odontogenic infections in Taiwan. J Microbiol Immunol Infect. 2003;36:105-10.
    • (2003) J Microbiol Immunol Infect. , vol.36 , pp. 105-110
    • Chan, Y.1    Chan, C.H.2
  • 20
    • 0027185165 scopus 로고
    • Characterization of a new class of tetracycline-resistance gene tet(S) in Listeria monocytogenes BM4210
    • Charpentier E, Gerbaud G, Courvalin P. Characterization of a new class of tetracycline-resistance gene tet(S) in Listeria monocytogenes BM4210. Gene. 1993;131:27-34.
    • (1993) Gene. , vol.131 , pp. 27-34
    • Charpentier, E.1    Gerbaud, G.2    Courvalin, P.3
  • 21
    • 0020378683 scopus 로고
    • The effect of short-term administration of minocycline HCI on gingival inflammation and subgingival microflora
    • Ciancio SG, Slots J, Reynolds HS, Zambon JJ, McKenna JD. The effect of short-term administration of minocycline HCI on gingival inflammation and subgingival microflora. J Periodontol. 1982;53:557-61.
    • (1982) J Periodontol. , vol.53 , pp. 557-561
    • Ciancio, S.G.1    Slots, J.2    Reynolds, H.S.3    Zambon, J.J.4    McKenna, J.D.5
  • 22
    • 62449204437 scopus 로고    scopus 로고
    • Amoxicilin and metronidazole as an adjunct to full-mouth scaling and root planning of chronic periodontitis
    • Cionca N, Giannopoulou C, Ugolotti G, Mombeli A. Amoxicilin and metronidazole as an adjunct to full-mouth scaling and root planning of chronic periodontitis. J Periodontol. 2009;80:364-71.
    • (2009) J Periodontol. , vol.80 , pp. 364-371
    • Cionca, N.1    Giannopoulou, C.2    Ugolotti, G.3    Mombeli, A.4
  • 23
    • 77649211628 scopus 로고    scopus 로고
    • Microbiologic testing and outcomes of full-mouth scaling and root planing with or without amoxicillin/metronidazole in chronic periodontitis
    • Cionca N, Giannopoulou C, Ugolotti G, Mombelli, A. Microbiologic testing and outcomes of full-mouth scaling and root planing with or without amoxicillin/metronidazole in chronic periodontitis. J Periodontol. 2010;81:15-23.
    • (2010) J Periodontol. , vol.81 , pp. 15-23
    • Cionca, N.1    Giannopoulou, C.2    Ugolotti, G.3    Mombelli, A.4
  • 24
    • 0024400856 scopus 로고
    • Cross-resistance to fluoroquinolones in multiple-antibioticresistant (Mar) Escherichia coli selected by tetracycline or choloramphenicol: Decreased drug accumulation associated with membrane changes in addition to OmpF reduction
    • Cohen SP, McMurry LM, Hooper DC, Wolfson JS, Levy SB. Cross-resistance to fluoroquinolones in multiple-antibioticresistant (Mar) Escherichia coli selected by tetracycline or choloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction. Antimicrob Agents Chemother. 1989;33:1318-25.
    • (1989) Antimicrob Agents Chemother. , vol.33 , pp. 1318-1325
    • Cohen, S.P.1    McMurry, L.M.2    Hooper, D.C.3    Wolfson, J.S.4    Levy, S.B.5
  • 25
    • 0024235788 scopus 로고
    • marA locus causes decreases expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli
    • Cohen SP, McMurry LM, Levy SB. marA locus causes decreases expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli. J Bacteriol. 1988;170:5416-22.
    • (1988) J Bacteriol. , vol.170 , pp. 5416-5422
    • Cohen, S.P.1    McMurry, L.M.2    Levy, S.B.3
  • 26
    • 0027434801 scopus 로고
    • Effects of a combination therapy to eliminate Porphyromonas gingivalis in refractory periodontitis
    • Collins JG, Offenbacher S, Arnold RR. Effects of a combination therapy to eliminate Porphyromonas gingivalis in refractory periodontitis. J Periodontol. 1993;64:998-1007.
    • (1993) J Periodontol. , vol.64 , pp. 998-1007
    • Collins, J.G.1    Offenbacher, S.2    Arnold, R.R.3
  • 28
    • 23444440823 scopus 로고
    • Inactivation of antibiotics and the dissemination of resistance genes
    • Davies J. Inactivation of antibiotics and the dissemination of resistance genes. Science. 1994;264:375-82.
    • (1994) Science. , vol.264 , pp. 375-382
    • Davies, J.1
  • 29
    • 0013930711 scopus 로고
    • Tetracycline inhibition of cell-free protein synthesis. II. Effect of the binding of tetracycline to the components of the system
    • Day LE. Tetracycline inhibition of cell-free protein synthesis. II. Effect of the binding of tetracycline to the components of the system. J Bacteriol. 1966;92 197-203.
    • (1966) J Bacteriol. , vol.92 , pp. 197-203
    • Day, L.E.1
  • 30
    • 77953214469 scopus 로고    scopus 로고
    • Response of chronic and aggressive periodontitis to treatment
    • Deas ED, Mealey LB. Response of chronic and aggressive periodontitis to treatment. Periodontol 2000. 2010;53:154-66.
    • (2010) Periodontol 2000. , vol.53 , pp. 154-166
    • Deas, E.D.1    Mealey, L.B.2
  • 31
    • 0025766901 scopus 로고
    • Susceptibility of Bacteroides ureolyticus to antimicrobial agents and identification of a tetracycline resistance determinant related to tetM
    • De Barbeyrac B, Dutilh B, Quentin C, Renaudin H, Bébéar C. Susceptibility of Bacteroides ureolyticus to antimicrobial agents and identification of a tetracycline resistance determinant related to tetM. J Antimicrob Chemother. 1991;27:721-31.
    • (1991) J Antimicrob Chemother. , vol.27 , pp. 721-731
    • de Barbeyrac, B.1    Dutilh, B.2    Quentin, C.3    Renaudin, H.4    Bébéar, C.5
  • 32
    • 0031950082 scopus 로고    scopus 로고
    • Molecular cloning and functional analysis of a novel tetracycline resistance determinant, tet(V), from Mycobacterium smegmatis
    • De Rossi E, Blokpoel MC, Cantoni R, Branzoni M, Riccardi G, Young DB, et al. Molecular cloning and functional analysis of a novel tetracycline resistance determinant, tet(V), from Mycobacterium smegmatis. Antimicrob Agents Chemother. 1998;42:1931-7.
    • (1998) Antimicrob Agents Chemother. , vol.42 , pp. 1931-1937
    • de Rossi, E.1    Blokpoel, M.C.2    Cantoni, R.3    Branzoni, M.4    Riccardi, G.5    Young, D.B.6    et al7
  • 33
    • 0026342866 scopus 로고
    • Characterization of an oxytetracycline-resistance gene, otrA, of Streptomyces rimosus
    • Doyle D, McDowall KJ, Butler MJ, Hunter IS. Characterization of an oxytetracycline-resistance gene, otrA, of Streptomyces rimosus. Mol Microbiol. 1991;5:2923-33.
    • (1991) Mol Microbiol. , vol.5 , pp. 2923-2933
    • Doyle, D.1    McDowall, K.J.2    Butler, M.J.3    Hunter, I.S.4
  • 37
    • 0025477027 scopus 로고
    • Doxycycline resistant bacteria in periodontally diseased individuals after systemic doxycycline therapy and in healthy individuals
    • Fiehn NE, Westergaard J. Doxycycline resistant bacteria in periodontally diseased individuals after systemic doxycycline therapy and in healthy individuals. Oral Microbiol Immunol. 1990;5:219-22.
    • (1990) Oral Microbiol Immunol. , vol.5 , pp. 219-222
    • Fiehn, N.E.1    Westergaard, J.2
  • 38
    • 0030703162 scopus 로고    scopus 로고
    • Metronidazole. A therapeutic review and update
    • Freeman CD, Klutman NE, Lamp KC. Metronidazole. A therapeutic review and update. Drugs. 1997;54:679-708.
    • (1997) Drugs. , vol.54 , pp. 679-708
    • Freeman, C.D.1    Klutman, N.E.2    Lamp, K.C.3
  • 39
    • 0030697489 scopus 로고    scopus 로고
    • Combination amoxicillin and metronidazole with famotidine in the eradication of Helicobacter pylori-a randomized, double-blind comparison of a three times daily and twice daily regimen
    • Goh KL, Parasakthi N, Chuah SY, Toetsch M. Combination amoxicillin and metronidazole with famotidine in the eradication of Helicobacter pylori-a randomized, double-blind comparison of a three times daily and twice daily regimen. Eur J Gastroenterol Hepatol. 1997;9:1091-5.
    • (1997) Eur J Gastroenterol Hepatol. , vol.9 , pp. 1091-1095
    • Goh, K.L.1    Parasakthi, N.2    Chuah, S.Y.3    Toetsch, M.4
  • 40
    • 0030862107 scopus 로고    scopus 로고
    • A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis
    • Golub LM, Lee HM, Greenwald RA, Ryan ME, Sorsa T, Salo T, et al. A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis. Inflamm Res. 1997;46:310-9.
    • (1997) Inflamm Res. , vol.46 , pp. 310-319
    • Golub, L.M.1    Lee, H.M.2    Greenwald, R.A.3    Ryan, M.E.4    Sorsa, T.5    Salo, T.6    et al7
  • 41
    • 0028457303 scopus 로고
    • Antimicrobial strategies for treatment of periodontal diseases
    • Goodson JM. Antimicrobial strategies for treatment of periodontal diseases. Periodontol 2000. 1994;5:142-68.
    • (1994) Periodontol 2000. , vol.5 , pp. 142-168
    • Goodson, J.M.1
  • 42
    • 0026844142 scopus 로고
    • Antibiotic resistance of the subgingival microbiota following local tetracycline therapy
    • Goodson JM, Tanner A. Antibiotic resistance of the subgingival microbiota following local tetracycline therapy. Oral Microbiol Immunol. 1992;7:113-7.
    • (1992) Oral Microbiol Immunol. , vol.7 , pp. 113-117
    • Goodson, J.M.1    Tanner, A.2
  • 43
    • 0023867424 scopus 로고
    • Prevention of nitroimidazole resistance in Campylobacter pylori by coadministration of colloidal bismuth subcitrate: Clinical and in vitro studies
    • Goodwin CS, Marshall BJ, Blincow ED, Wilson DH, Blackbourn S, Phillips M. Prevention of nitroimidazole resistance in Campylobacter pylori by coadministration of colloidal bismuth subcitrate: clinical and in vitro studies. J Clin Pathol. 1988;41:207-10.
    • (1988) J Clin Pathol. , vol.41 , pp. 207-210
    • Goodwin, C.S.1    Marshall, B.J.2    Blincow, E.D.3    Wilson, D.H.4    Blackbourn, S.5    Phillips, M.6
  • 44
    • 0030751497 scopus 로고    scopus 로고
    • Twice a day quadruple therapy (bismuth subsalicylate, tetracycline, metronidazole plus lansoprazole) for treatment of Helicobacter pylori infection
    • Graham DY, Hoffman J, el-Zimaity HM, Graham DP, Osato M. Twice a day quadruple therapy (bismuth subsalicylate, tetracycline, metronidazole plus lansoprazole) for treatment of Helicobacter pylori infection. Aliment Pharmacol Ther. 1997;11:935-8.
    • (1997) Aliment Pharmacol Ther. , vol.11 , pp. 935-938
    • Graham, D.Y.1    Hoffman, J.2    el-Zimaity, H.M.3    Graham, D.P.4    Osato, M.5
  • 45
    • 25844497516 scopus 로고    scopus 로고
    • Adjuntive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: A randomized placebo-contolled clinical trial
    • Guerrero A, Griffiths GS, Nibali L, Suvan J, Moles DR, Laurell L, et al. Adjuntive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: a randomized placebo-contolled clinical trial. J Clin Periodontol. 2005;32:1096-107.
    • (2005) J Clin Periodontol. , vol.32 , pp. 1096-1107
    • Guerrero, A.1    Griffiths, G.S.2    Nibali, L.3    Suvan, J.4    Moles, D.R.5    Laurell, L.6    et al7
  • 46
    • 0025020744 scopus 로고
    • Detection of conjugal transfer systems in oral, black-pigmented Bacteroides spp
    • Guiney DG, Bouic K. Detection of conjugal transfer systems in oral, black-pigmented Bacteroides spp. J Bacteriol. 1990;172:495-7.
    • (1990) J Bacteriol. , vol.172 , pp. 495-497
    • Guiney, D.G.1    Bouic, K.2
  • 47
    • 0021127080 scopus 로고
    • Expression in Escherichia coli of cryptic tetracycline resistance genes from Bacteroides R plasmids
    • Guiney DG Jr, Hasegawa P, Davis CE. Expression in Escherichia coli of cryptic tetracycline resistance genes from Bacteroides R plasmids. Plasmid. 1989;11:248-52.
    • (1989) Plasmid. , vol.11 , pp. 248-252
    • Guiney Jr, D.G.1    Hasegawa, P.2    Davis, C.E.3
  • 48
    • 0024313405 scopus 로고
    • Methicillin-resistant staphylococci: Genetics and mechanisms of resistance
    • Hackbarth CJ, Chambers HF. Methicillin-resistant staphylococci: genetics and mechanisms of resistance. Antimicrob Agents Chemother. 1989;33:991-4.
    • (1989) Antimicrob Agents Chemother. , vol.33 , pp. 991-994
    • Hackbarth, C.J.1    Chambers, H.F.2
  • 49
    • 0029349715 scopus 로고
    • Clinical and microbiological changes associated with the use of 4 adjunctive systemically administered agents in the treatment of periodontal infections
    • Haffajee AD, Dibart S, Kent RL Jr, Socransky SS. Clinical and microbiological changes associated with the use of 4 adjunctive systemically administered agents in the treatment of periodontal infections. J Clin Periodontol. 1995;22:618-27.
    • (1995) J Clin Periodontol. , vol.22 , pp. 618-627
    • Haffajee, A.D.1    Dibart, S.2    Kent Jr., R.L.3    Socransky, S.S.4
  • 51
    • 39049173083 scopus 로고    scopus 로고
    • Microbiological changes associated with four different periodontal therapies for the treatment of chronic periodontitis
    • Haffajee AD, Patel M, Socransky SS. Microbiological changes associated with four different periodontal therapies for the treatment of chronic periodontitis. Oral Microbiol Immunol. 2008;23:148-57.
    • (2008) Oral Microbiol Immunol. , vol.23 , pp. 148-157
    • Haffajee, A.D.1    Patel, M.2    Socransky, S.S.3
  • 52
    • 33846931770 scopus 로고    scopus 로고
    • Clinical changes following four different periodontal therapies for the treatment of chronic periodontitis: 1-year results
    • Haffajee AD, Torresyap G, Socransky SS. Clinical changes following four different periodontal therapies for the treatment of chronic periodontitis: 1-year results. J Clin Periodontol. 2007;34:243-53.
    • (2007) J Clin Periodontol. , vol.34 , pp. 243-253
    • Haffajee, A.D.1    Torresyap, G.2    Socransky, S.S.3
  • 53
    • 0028356986 scopus 로고
    • Nucleotide sequence analysis of two 5-nitromidazole resistance determinants from Bacteroides strains and of a new insertion sequence upstream of the two genes
    • Haggoud A, Reysset G, Azeddoug H, Sebald M. Nucleotide sequence analysis of two 5-nitromidazole resistance determinants from Bacteroides strains and of a new insertion sequence upstream of the two genes. Antimicrob Agents Chemother. 1994;38:1047-51.
    • (1994) Antimicrob Agents Chemother. , vol.38 , pp. 1047-1051
    • Haggoud, A.1    Reysset, G.2    Azeddoug, H.3    Sebald, M.4
  • 54
    • 0031945139 scopus 로고    scopus 로고
    • Resistant penicillin-binding proteins
    • Hakenbeck R, Coyette J. Resistant penicillin-binding proteins. Cell Mol Life Sci. 1998;54:332-40.
    • (1998) Cell Mol Life Sci. , vol.54 , pp. 332-340
    • Hakenbeck, R.1    Coyette, J.2
  • 55
    • 4544369003 scopus 로고    scopus 로고
    • β-lactamase protection and antimicrobial susceptibility of subgingival bacteria from refractory periodontitis
    • Handal T, Olsen I, Walker CB, Caugant DA. β-lactamase protection and antimicrobial susceptibility of subgingival bacteria from refractory periodontitis. Oral Microbiol Immunol. 2004;19:303-8.
    • (2004) Oral Microbiol Immunol. , vol.19 , pp. 303-308
    • Handal, T.1    Olsen, I.2    Walker, C.B.3    Caugant, D.A.4
  • 56
    • 0027486151 scopus 로고
    • A new tetracycline resistance determinant, Tet H, from Pasteurella multocida specifying active efflux of tetracycline
    • Hansen LM, McMurry LM, Levy SB, Hirsh DC. A new tetracycline resistance determinant, Tet H, from Pasteurella multocida specifying active efflux of tetracycline. Antimicrob Agents Chemother. 1993;37:2699-705.
    • (1993) Antimicrob Agents Chemother. , vol.37 , pp. 2699-2705
    • Hansen, L.M.1    McMurry, L.M.2    Levy, S.B.3    Hirsh, D.C.4
  • 57
    • 50249142996 scopus 로고    scopus 로고
    • Antimicrobial therapy in periodontitis: The use of systemic antimicrobials against the subgingival biofi{ligature}lm
    • Herrera D, Alonso B, León R, Roldán S, Sanz M. Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofi{ligature}lm. J Clin Periodontol. 2008;35(Suppl. 8):45-66.
    • (2008) J Clin Periodontol. , vol.35 , Issue.SUPPL. 8 , pp. 45-66
    • Herrera, D.1    Alonso, B.2    León, R.3    Roldán, S.4    Sanz, M.5
  • 59
    • 0029020383 scopus 로고
    • Azithromycin: The first of the tissue-selective azalides
    • Hoepelman IM, Schneider MM. Azithromycin: the first of the tissue-selective azalides. Int J Antimicrob Agents. 1995;5(3):145-67.
    • (1995) Int J Antimicrob Agents. , vol.5 , Issue.3 , pp. 145-167
    • Hoepelman, I.M.1    Schneider, M.M.2
  • 60
    • 0026686863 scopus 로고
    • Susceptibilities of members of the Bacteroides fragilis group to 11 antimicrobial agents
    • Horn R, Lavallée J, Robson HG. Susceptibilities of members of the Bacteroides fragilis group to 11 antimicrobial agents. Antimicrob Agents Chemother. 1992;36;2051-3.
    • (1992) Antimicrob Agents Chemother. , vol.36 , pp. 2051-2053
    • Horn, R.1    Lavallée, J.2    Robson, H.G.3
  • 61
    • 0022249552 scopus 로고
    • Nucleotide sequence of the tetracycline resistance gene of pTHT15, a thermophilic Bacillus plasmid: Comparison with staphylococcal TcR controls
    • Hoshino T, Ikeda T, Tomizuka N, Furukawa K. Nucleotide sequence of the tetracycline resistance gene of pTHT15, a thermophilic Bacillus plasmid: comparison with staphylococcal TcR controls. Gene. 1985;37:131-8.
    • (1985) Gene. , vol.37 , pp. 131-138
    • Hoshino, T.1    Ikeda, T.2    Tomizuka, N.3    Furukawa, K.4
  • 62
    • 0345687927 scopus 로고    scopus 로고
    • Quinolone resistance due to reduced target enzyme expression
    • Ince D, Hooper DC. Quinolone resistance due to reduced target enzyme expression. J Bacteriol. 2003;185:6883-92.
    • (2003) J Bacteriol. , vol.185 , pp. 6883-6892
    • Ince, D.1    Hooper, D.C.2
  • 63
    • 0017798624 scopus 로고
    • Bacteroides fragilis resistant to metronidazole after long-term therapy
    • Ingham HR, Eaton S, Venables CW, Adams PC. Bacteroides fragilis resistant to metronidazole after long-term therapy. Lancet. 1978;1:214.
    • (1978) Lancet. , vol.1 , pp. 214
    • Ingham, H.R.1    Eaton, S.2    Venables, C.W.3    Adams, P.C.4
  • 64
    • 0035102304 scopus 로고    scopus 로고
    • Foustoukou M, Legakis NJ, Vatopoulos A. Antibiotic resistance rates and macrolide resistance phenotypes of viridians group streptococci from the oropharynx of healthy Greek children
    • Ioannidou S, Tassios PT, Kotsovili-Tseleni A. Foustoukou M, Legakis NJ, Vatopoulos A. Antibiotic resistance rates and macrolide resistance phenotypes of viridians group streptococci from the oropharynx of healthy Greek children. Int J Antimicrob Agents. 2001;17:195-201.
    • (2001) Int J Antimicrob Agents. , vol.17 , pp. 195-201
    • Ioannidou, S.1    Tassios, P.T.2    Kotsovili-Tseleni, A.3
  • 65
    • 0028936652 scopus 로고
    • Bacterial vaginosis: Review of treatment options and potential clinical indications for therapy
    • Joesoef MR, Schmid GP. Bacterial vaginosis: review of treatment options and potential clinical indications for therapy. Clin Infect Dis. 1995;20:S72-9.
    • (1995) Clin Infect Dis. , vol.20
    • Joesoef, M.R.1    Schmid, G.P.2
  • 66
    • 0025130196 scopus 로고
    • Antimicrobial resistance among respiratory isolates of Haemophilus influenza, Moraxella catarrhalis, and Streptococcus pneumonia in the United States
    • Jorgensen JH, Doern GV, Maher LA, Howell AW, Redding JS. Antimicrobial resistance among respiratory isolates of Haemophilus influenza, Moraxella catarrhalis, and Streptococcus pneumonia in the United States. Antimicrob Agents Chemother. 1990;34:2075-80.
    • (1990) Antimicrob Agents Chemother. , vol.34 , pp. 2075-2080
    • Jorgensen, J.H.1    Doern, G.V.2    Maher, L.A.3    Howell, A.W.4    Redding, J.S.5
  • 67
    • 15744392285 scopus 로고    scopus 로고
    • Bacterial efflux pump inhibition
    • Kaatz GW. Bacterial efflux pump inhibition. Curr Opin Investig Drugs. 2005;6:191-8.
    • (2005) Curr Opin Investig Drugs. , vol.6 , pp. 191-198
    • Kaatz, G.W.1
  • 68
    • 0002694846 scopus 로고    scopus 로고
    • Antimicrobial agents: Penicillins, cephalosporins, and other beta-lactam antibiotics
    • In: Gilman AG, Hardman JG, Limbird LE, New York: Pergamon Press
    • Kapusnik-Uner JE, Sande MA, Chambers HF. Antimicrobial agents: penicillins, cephalosporins, and other beta-lactam antibiotics. In: Gilman AG, Hardman JG, Limbird LE. The pharmacological basis of therapeutic. New York: Pergamon Press; 1996. p. 1123-53.
    • (1996) The pharmacological basis of therapeutic , pp. 1123-1153
    • Kapusnik-Uner, J.E.1    Sande, M.A.2    Chambers, H.F.3
  • 69
    • 80052286322 scopus 로고    scopus 로고
    • Characterization of antibiotic resistance determinants in oral biofilms
    • Kim SM, Kim HC, Lee SW. Characterization of antibiotic resistance determinants in oral biofilms. J Microb. 2011;49:594-602.
    • (2011) J Microb. , vol.49 , pp. 594-602
    • Kim, S.M.1    Kim, H.C.2    Lee, S.W.3
  • 70
    • 0022653929 scopus 로고
    • Penicillin resistance in the subgingival microbiota associated with adult periodontitis
    • Kinder SA, Holt SC, Korman KS. Penicillin resistance in the subgingival microbiota associated with adult periodontitis. J Clin Microbiol. 1986;23:1127-33.
    • (1986) J Clin Microbiol. , vol.23 , pp. 1127-1133
    • Kinder, S.A.1    Holt, S.C.2    Korman, K.S.3
  • 71
    • 0036462999 scopus 로고    scopus 로고
    • Erythromycin susceptibility of viridans streptococci from the normal throat flora of patients treated with azithromycin or clarithromycin
    • King A, Bathgate T, Phillips I. Erythromycin susceptibility of viridans streptococci from the normal throat flora of patients treated with azithromycin or clarithromycin. Clin Microbiol Infect. 2002;8:85-92.
    • (2002) Clin Microbiol Infect. , vol.8 , pp. 85-92
    • King, A.1    Bathgate, T.2    Phillips, I.3
  • 72
    • 0020368812 scopus 로고
    • The effect of long-term low-dose tetracycline therapy on the subgingival microflora in refractory adult periodontitis
    • Kornman KS, Karl EH. The effect of long-term low-dose tetracycline therapy on the subgingival microflora in refractory adult periodontitis. J Periodontol. 1982;53:604-10.
    • (1982) J Periodontol. , vol.53 , pp. 604-610
    • Kornman, K.S.1    Karl, E.H.2
  • 73
    • 0020354038 scopus 로고
    • Antibiotic susceptibility of black-pigmented Bacteroides isolates from the human oral cavity
    • Laatsch LJ. Hohenfeldt PR, Kos WL. Antibiotic susceptibility of black-pigmented Bacteroides isolates from the human oral cavity. Antimicrob Agents Chemother. 1982;22:698-700.
    • (1982) Antimicrob Agents Chemother. , vol.22 , pp. 698-700
    • Laatsch, L.J.1    Hohenfeldt, P.R.2    Kos, W.L.3
  • 74
    • 0028894070 scopus 로고
    • Detection and incidence of the tetracycline resistance determinant tet(M) in the microflora associated with adult periodontitis
    • Lacroix JM, Walker CB. Detection and incidence of the tetracycline resistance determinant tet(M) in the microflora associated with adult periodontitis. J Periodontol. 1995;66:102-8.
    • (1995) J Periodontol. , vol.66 , pp. 102-108
    • Lacroix, J.M.1    Walker, C.B.2
  • 75
    • 0030206368 scopus 로고    scopus 로고
    • Detection and prevalence of the tetracycline resistance determinant Tet Q in the microbiota associated with adult periodontitis
    • Lacroix JM, Walker CB. Detection and prevalence of the tetracycline resistance determinant Tet Q in the microbiota associated with adult periodontitis. Oral Microbiol Immunol. 1996;11:282-8.
    • (1996) Oral Microbiol Immunol. , vol.11 , pp. 282-288
    • Lacroix, J.M.1    Walker, C.B.2
  • 76
    • 0036801473 scopus 로고    scopus 로고
    • Susceptibility of Porphyromonas gingivalis in biofilms to amoxicillin, doxycycline and metronidazole
    • Larsen T. Susceptibility of Porphyromonas gingivalis in biofilms to amoxicillin, doxycycline and metronidazole. Oral Microbiol Immunol. 2002;17:267-71.
    • (2002) Oral Microbiol Immunol. , vol.17 , pp. 267-271
    • Larsen, T.1
  • 77
    • 0031115496 scopus 로고    scopus 로고
    • Development of resistance to metronidazole and minocycline in vitro
    • Larsen T, Fiehn NE. Development of resistance to metronidazole and minocycline in vitro. J Clin Periodontol. 1997; 24: 254-259.
    • (1997) J Clin Periodontol. , vol.24 , pp. 254-259
    • Larsen, T.1    Fiehn, N.E.2
  • 78
    • 0023683819 scopus 로고
    • Nucleotide sequence analysis of tetracycline resistance gene tetO from Streptococcus mutans DL5
    • LeBlanc DJ, Lee LN, Titmas BM, Smith CJ, Tenover FC. Nucleotide sequence analysis of tetracycline resistance gene tetO from Streptococcus mutans DL5. J Bacteriol. 1988;170:3618-26.
    • (1988) J Bacteriol. , vol.170 , pp. 3618-3626
    • LeBlanc, D.J.1    Lee, L.N.2    Titmas, B.M.3    Smith, C.J.4    Tenover, F.C.5
  • 79
    • 0037083024 scopus 로고    scopus 로고
    • Mechanisms of resistance to macrolides and lincosamides: Nature of the resistance elements and their clinical implications
    • Leclercq R. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin Infect Dis. 2002;34:482-92.
    • (2002) Clin Infect Dis. , vol.34 , pp. 482-492
    • Leclercq, R.1
  • 80
    • 0024412969 scopus 로고
    • Evolution and spread of tetracycline resistance determinants
    • Levy SB. Evolution and spread of tetracycline resistance determinants. J Antimicrob Chemother. 1989;24:1-3.
    • (1989) J Antimicrob Chemother. , vol.24 , pp. 1-3
    • Levy, S.B.1
  • 81
    • 0442307441 scopus 로고    scopus 로고
    • Efflux-mediated drug resistance in bacteria
    • Li XZ, Nikaido H. Efflux-mediated drug resistance in bacteria. Drugs. 2004;64:159-204.
    • (2004) Drugs. , vol.64 , pp. 159-204
    • Li, X.Z.1    Nikaido, H.2
  • 82
    • 0027262947 scopus 로고
    • Microbial composition and pattern of antibiotic resistance in subgingival microbial samples from patients with refractory periodontitis
    • Listgarten MA, Lai CH, Young V. Microbial composition and pattern of antibiotic resistance in subgingival microbial samples from patients with refractory periodontitis. J Periodontol. 1993;64:155-61.
    • (1993) J Periodontol. , vol.64 , pp. 155-161
    • Listgarten, M.A.1    Lai, C.H.2    Young, V.3
  • 84
  • 85
    • 0026720445 scopus 로고
    • Comparison of different metronidazole therapeutic regiments for bacterial vaginosis. A meta-analysis
    • Lugo-Miro VI, Green M, Mazur L. Comparison of different metronidazole therapeutic regiments for bacterial vaginosis. A meta-analysis. JAMA. 1992;268:92-5.
    • (1992) JAMA. , vol.268 , pp. 92-95
    • Lugo-Miro, V.I.1    Green, M.2    Mazur, L.3
  • 86
    • 34250820462 scopus 로고    scopus 로고
    • Odontogenic bacteria in periodontal disease and resistance patterns to common antibiotics used as treatment and prophylaxis in odontology in Spain
    • Maestre JR, Bascones A, Sánchez P, Matesanz P, Aguilar L, Giménez MJ, et al. Odontogenic bacteria in periodontal disease and resistance patterns to common antibiotics used as treatment and prophylaxis in odontology in Spain. Rev Esp Quimioter. 2007;20:61-7.
    • (2007) Rev Esp Quimioter. , vol.20 , pp. 61-67
    • Maestre, J.R.1    Bascones, A.2    Sánchez, P.3    Matesanz, P.4    Aguilar, L.5    Giménez, M.J.6    et al7
  • 88
    • 0025818509 scopus 로고
    • Clinical, microbiological and immunological characteristics of subjects with "refractory" periodontal disease
    • Magnusson I, Marks RG, Clark WB, Walker CB, Low SB, McArthur WP. Clinical, microbiological and immunological characteristics of subjects with "refractory" periodontal disease. J Clin Periodontol. 1991;18:291-9.
    • (1991) J Clin Periodontol. , vol.18 , pp. 291-299
    • Magnusson, I.1    Marks, R.G.2    Clark, W.B.3    Walker, C.B.4    Low, S.B.5    McArthur, W.P.6
  • 89
    • 0000982054 scopus 로고    scopus 로고
    • Antimicrobial agents: Penicillins, cephalosporins, and other beta-lactam antibiotics
    • In: Gilman AG, Hardman JG, Limbird LE, New York: Pergamon Press
    • Mandell GL, Phillips RW. Antimicrobial agents: penicillins, cephalosporins, and other beta-lactam antibiotics. In: Gilman AG, Hardman JG, Limbird LE. The pharmacological basis of therapeutic. New York: Pergamon Press; 1996. p. 1073-101.
    • (1996) The pharmacological basis of therapeutic , pp. 1073-1101
    • Mandell, G.L.1    Phillips, R.W.2
  • 90
    • 0014238955 scopus 로고
    • Studies of the binding of thetracycline to ribosomes in vitro
    • Maxwell IH. Studies of the binding of thetracycline to ribosomes in vitro. Mol Pharmacol. 1968;4:25-37.
    • (1968) Mol Pharmacol. , vol.4 , pp. 25-37
    • Maxwell, I.H.1
  • 91
    • 0345515642 scopus 로고
    • Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli
    • McMurry L, Petrucci RE Jr, Levy SB. Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli. Proc Natl Acad Sci USA. 1980;77:3974-7.
    • (1980) Proc Natl Acad Sci USA. , vol.77 , pp. 3974-3977
    • McMurry, L.1    Petrucci Jr., R.E.2    Levy, S.B.3
  • 92
    • 0023269955 scopus 로고
    • Energy-dependent efflux mediated by class L (tetL) tetracycline resistance determinant from streptococci
    • McMurry LM, Park BH, Burdett V, Levy SB. Energy-dependent efflux mediated by class L (tetL) tetracycline resistance determinant from streptococci. Antimicrob Agents Chemother. 1987;31:1648-50.
    • (1987) Antimicrob Agents Chemother. , vol.31 , pp. 1648-1650
    • McMurry, L.M.1    Park, B.H.2    Burdett, V.3    Levy, S.B.4
  • 93
    • 1042284860 scopus 로고    scopus 로고
    • Antibiotic resistance in Helicobacter pylori infection
    • Mégraud F. Antibiotic resistance in Helicobacter pylori infection. Br Med Bull. 1998;54:207-16.
    • (1998) Br Med Bull. , vol.54 , pp. 207-216
    • Mégraud, F.1
  • 94
    • 77949769804 scopus 로고    scopus 로고
    • Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis
    • Mestnik MJ, Feres M, Figueiredo LC, Duarte PM, Lira EAG, Faveri M. Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis. J Clin Periodontol. 2010;37:353-65.
    • (2010) J Clin Periodontol. , vol.37 , pp. 353-365
    • Mestnik, M.J.1    Feres, M.2    Figueiredo, L.C.3    Duarte, P.M.4    Lira, E.A.G.5    Faveri, M.6
  • 96
    • 0036673434 scopus 로고    scopus 로고
    • In vitro antimicrobial susceptibility of oral strains of Actinobacillus actinomycetencomitans to seven antibiotics
    • Müller HP, Holderrieth S, Burkhardt U, Höffler U. In vitro antimicrobial susceptibility of oral strains of Actinobacillus actinomycetencomitans to seven antibiotics. J Clin Periodontol. 2002;29:736-42.
    • (2002) J Clin Periodontol. , vol.29 , pp. 736-742
    • Müller, H.P.1    Holderrieth, S.2    Burkhardt, U.3    Höffler, U.4
  • 97
    • 0020536580 scopus 로고
    • Mode of action of metronidazole on anaerobic bacteria and protozoa
    • Müller M. Mode of action of metronidazole on anaerobic bacteria and protozoa. Surgery. 1983;93:165-71.
    • (1983) Surgery. , vol.93 , pp. 165-171
    • Müller, M.1
  • 98
    • 0022571666 scopus 로고
    • Outer-membrane permeability of bacteria
    • Nakae T. Outer-membrane permeability of bacteria. Crit Rev Microbiol. 1986;13:1-62.
    • (1986) Crit Rev Microbiol. , vol.13 , pp. 1-62
    • Nakae, T.1
  • 99
    • 0025054630 scopus 로고
    • Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistance strain of Staphylococcus aureus
    • Nesin M, Svec P, Lupski JR, Godson GN, Kreiswirth B, Kornblum J, et al. Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistance strain of Staphylococcus aureus. Antimicrob Agents Chemother. 1990;34:2273-6.
    • (1990) Antimicrob Agents Chemother. , vol.34 , pp. 2273-2276
    • Nesin, M.1    Svec, P.2    Lupski, J.R.3    Godson, G.N.4    Kreiswirth, B.5    Kornblum, J.6    et al7
  • 100
    • 65249146929 scopus 로고    scopus 로고
    • Multidrug resistance in bacteria
    • Nikaido H. Multidrug resistance in bacteria. Annu Rev Biochem. 2009;78:119-46.
    • (2009) Annu Rev Biochem. , vol.78 , pp. 119-146
    • Nikaido, H.1
  • 101
    • 23444456920 scopus 로고
    • Prevention of drug access to bacterial targets: Permeabitity barriers and active aafflux
    • Nikaido H. Prevention of drug access to bacterial targets: permeabitity barriers and active aafflux. Science. 1994;264:382-8.
    • (1994) Science. , vol.264 , pp. 382-388
    • Nikaido, H.1
  • 102
    • 0026649822 scopus 로고
    • A Bacteroides tetracycline resistance gene represents a new class of ribosome protection tetracycline resistance
    • Nikolich MP, Shoemaker NB, Salyers AA. A Bacteroides tetracycline resistance gene represents a new class of ribosome protection tetracycline resistance. Antimicrob Agents Chemother. 1992;36:1005-12.
    • (1992) Antimicrob Agents Chemother. , vol.36 , pp. 1005-1012
    • Nikolich, M.P.1    Shoemaker, N.B.2    Salyers, A.A.3
  • 103
    • 0037256807 scopus 로고    scopus 로고
    • Emergence of penicillin resistance among Fusobacterium nucleatum populations of commensal oral flora during early childhood
    • Nyfors S, Könönen E, Syrjänen R, Komulainen E, Jousimies-Somer H. Emergence of penicillin resistance among Fusobacterium nucleatum populations of commensal oral flora during early childhood. J Antimicrob Chemother. 2003;51:107-12.
    • (2003) J Antimicrob Chemother. , vol.51 , pp. 107-112
    • Nyfors, S.1    Könönen, E.2    Syrjänen, R.3    Komulainen, E.4    Jousimies-Somer, H.5
  • 104
    • 0030264534 scopus 로고    scopus 로고
    • Tetracycline resistance in Prevotella isolates from periodontally diseased patients in due to the tet(Q) gene
    • Olsvik B, Flynn MJ, Tenover FC, Slots J, Olsen I. Tetracycline resistance in Prevotella isolates from periodontally diseased patients in due to the tet(Q) gene. Oral Microbiol Immunol. 1996;11:304-8.
    • (1996) Oral Microbiol Immunol. , vol.11 , pp. 304-308
    • Olsvik, B.1    Flynn, M.J.2    Tenover, F.C.3    Slots, J.4    Olsen, I.5
  • 105
    • 0029298384 scopus 로고
    • Tetracyclineresistant micro-organisms recovered from patients with refractory periodontal disease
    • Olsvik B, Hansen BF, Tenover FC, Olsen I. Tetracyclineresistant micro-organisms recovered from patients with refractory periodontal disease. J Clin Periodontol. 1995;22:391-6.
    • (1995) J Clin Periodontol. , vol.22 , pp. 391-396
    • Olsvik, B.1    Hansen, B.F.2    Tenover, F.C.3    Olsen, I.4
  • 106
    • 0029278874 scopus 로고
    • Detection of tet(M) and tet(O) using the polymerase chain reaction in bacteria isolated from patients with periodontal disease
    • Osvik B, Olsen I, Tenover FC. Detection of tet(M) and tet(O) using the polymerase chain reaction in bacteria isolated from patients with periodontal disease. Oral Microbiol Immunol. 1995;10:87-92.
    • (1995) Oral Microbiol Immunol. , vol.10 , pp. 87-92
    • Osvik, B.1    Olsen, I.2    Tenover, F.C.3
  • 107
    • 0028485635 scopus 로고
    • The tet(Q) gene in bacteria isolated from patients with refractory periodontal disease
    • Olsvik B, Olsen I, Tenover FC. The tet(Q) gene in bacteria isolated from patients with refractory periodontal disease. Oral Microbiol Immunol. 1994;9:251-5.
    • (1994) Oral Microbiol Immunol. , vol.9 , pp. 251-255
    • Olsvik, B.1    Olsen, I.2    Tenover, F.C.3
  • 108
    • 0030260744 scopus 로고    scopus 로고
    • Three subtypes of tet(M) gene identified in bacterial isolates from periodontal pockets
    • Olsvik B, Tenover FC, Olsen I, Rasheed JK. Three subtypes of tet(M) gene identified in bacterial isolates from periodontal pockets. Oral Microbiol Immunol. 1996;11:299-303.
    • (1996) Oral Microbiol Immunol. , vol.11 , pp. 299-303
    • Olsvik, B.1    Tenover, F.C.2    Olsen, I.3    Rasheed, J.K.4
  • 109
    • 0017342347 scopus 로고
    • Tetracycline inhibits propagation of deoxyribonucleic acid replication and alters membrane properties
    • Pato ML. Tetracycline inhibits propagation of deoxyribonucleic acid replication and alters membrane properties. Antimicrob Agents Chemother. 1977;11:318-323.
    • (1977) Antimicrob Agents Chemother. , vol.11 , pp. 318-323
    • Pato, M.L.1
  • 110
    • 0034406527 scopus 로고    scopus 로고
    • Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin
    • Poulsen SM, Kofoed C, Vester B. Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin. J Mol Biol. 2000;304:471-81.
    • (2000) J Mol Biol. , vol.304 , pp. 471-481
    • Poulsen, S.M.1    Kofoed, C.2    Vester, B.3
  • 111
    • 0026583186 scopus 로고
    • Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis
    • Quon DV, d'Oliveira CE, Johnson PJ. Reduced transcription of the ferredoxin gene in metronidazole-resistant Trichomonas vaginalis. Proc Natl Acad Sci U.S.A. 1992;89:4402-6.
    • (1992) Proc Natl Acad Sci U.S. A. , vol.89 , pp. 4402-4406
    • Quon, D.V.1    d'Oliveira, C.E.2    Johnson, P.J.3
  • 114
    • 0842264381 scopus 로고    scopus 로고
    • Prevalence, proportions, and identities of antibiotic-resistant bacteria in the oral microflora of healthy children
    • Ready D, Bedi R, Spratt DA, Mullany P, Wilson M. Prevalence, proportions, and identities of antibiotic-resistant bacteria in the oral microflora of healthy children. Microb Drugs Resist. 2003;9:367-72.
    • (2003) Microb Drugs Resist. , vol.9 , pp. 367-372
    • Ready, D.1    Bedi, R.2    Spratt, D.A.3    Mullany, P.4    Wilson, M.5
  • 115
    • 0036001174 scopus 로고    scopus 로고
    • Composition and antibiotic resistance profile of microcosm dental plaques before and after exposure to tetracycline
    • Ready D, Roberts AP, Pratten J. Spratt DA, Wilson M, Mullany P. Composition and antibiotic resistance profile of microcosm dental plaques before and after exposure to tetracycline. J Antimicrob Chemother. 2002;49:769-75.
    • (2002) J Antimicrob Chemother. , vol.49 , pp. 769-775
    • Ready, D.1    Roberts, A.P.2    Pratten, J.3    Spratt, D.A.4    Wilson, M.5    Mullany, P.6
  • 116
    • 0029946288 scopus 로고    scopus 로고
    • Genetics of 5-nitroimidazole resistance in Bacteroides species
    • Reysset G. Genetics of 5-nitroimidazole resistance in Bacteroides species. Anaerobe. 1996;2:59-69.
    • (1996) Anaerobe. , vol.2 , pp. 59-69
    • Reysset, G.1
  • 117
    • 0036364268 scopus 로고    scopus 로고
    • Antibiotic toxicity, interactions and resistance development
    • Roberts MC. Antibiotic toxicity, interactions and resistance development. Periodontol 2000. 2002;28:280-97.
    • (2002) Periodontol 2000. , vol.28 , pp. 280-297
    • Roberts, M.C.1
  • 118
    • 0030273002 scopus 로고    scopus 로고
    • Tetracycline resistance determinants: Mechanisms of action, regulation of expression, genetic mobility, and distribution
    • Roberts MC. Tetracycline resistance determinants: mechanisms of action, regulation of expression, genetic mobility, and distribution. FEMS Microbiol Rev. 1996;19:1-24.
    • (1996) FEMS Microbiol Rev. , vol.19 , pp. 1-24
    • Roberts, M.C.1
  • 119
    • 0025100892 scopus 로고
    • Genetic basis of tetracycline resistance in urogenital bacteria
    • Roberts MC, Hillier SL. Genetic basis of tetracycline resistance in urogenital bacteria. Antimicrob Agents Chemother. 1990;34:261-4.
    • (1990) Antimicrob Agents Chemother. , vol.34 , pp. 261-264
    • Roberts, M.C.1    Hillier, S.L.2
  • 121
    • 0023730716 scopus 로고
    • Tetracycline resistance and TetM in oral anaerobic bacteria and Neisseria perflava-N. sicca
    • Roberts MC, Moncla BJ. Tetracycline resistance and TetM in oral anaerobic bacteria and Neisseria perflava-N. sicca. Antimicrob Agents Chemother. 1988;32:1271-3.
    • (1988) Antimicrob Agents Chemother. , vol.32 , pp. 1271-1273
    • Roberts, M.C.1    Moncla, B.J.2
  • 122
    • 0025992980 scopus 로고
    • Tetracycline resistance in Moraxella (Branhamella) catarrhalis: Demonstration of two clonal outbreaks by using pulsed-field gel electrophoresis
    • Roberts MC, Pang YJ, Spencer RC, Winstanley TG, Brown BA, Wallace RJ Jr. Tetracycline resistance in Moraxella (Branhamella) catarrhalis: demonstration of two clonal outbreaks by using pulsed-field gel electrophoresis. Antimicrob Agents Chemother. 1991;35:2453-5.
    • (1991) Antimicrob Agents Chemother. , vol.35 , pp. 2453-2455
    • Roberts, M.C.1    Pang, Y.J.2    Spencer, R.C.3    Winstanley, T.G.4    Brown, B.A.5    Wallace Jr., R.J.6
  • 124
    • 30044445411 scopus 로고    scopus 로고
    • Fluoroquinolone-modifying enzyme: A new adaptation of a common aminoglycoside acetyltransferase
    • Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, et al. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med. 2006;12:83-8.
    • (2006) Nat Med. , vol.12 , pp. 83-88
    • Robicsek, A.1    Strahilevitz, J.2    Jacoby, G.A.3    McIelag, M.4    Abbanat, D.5    Park, C.H.6    et al7
  • 127
    • 0036780063 scopus 로고    scopus 로고
    • Presence and antibiotic resistance of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens in children
    • Sanai Y, Persson GR, Starr JR, Luis HS, Bernardo M, Leitao J, et al. Presence and antibiotic resistance of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens in children. J Clin Periodontol. 2002;29:929-34.
    • (2002) J Clin Periodontol. , vol.29 , pp. 929-934
    • Sanai, Y.1    Persson, G.R.2    Starr, J.R.3    Luis, H.S.4    Bernardo, M.5    Leitao, J.6    et al7
  • 128
    • 0021684516 scopus 로고
    • Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes
    • Sanders CC, Sanders WE Jr, Goering RV, Werner V. Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes. Antimicrob Agents Chemother. 1984;26:797-801.
    • (1984) Antimicrob Agents Chemother. , vol.26 , pp. 797-801
    • Sanders, C.C.1    Sanders Jr., W.E.2    Goering, R.V.3    Werner, V.4
  • 129
    • 0023750184 scopus 로고
    • Emergence of antibiotic resistant strains of Bacteroides fragilis
    • Scher KS. Emergence of antibiotic resistant strains of Bacteroides fragilis. Surg Gynecol Obstet. 1988;167:175-9.
    • (1988) Surg Gynecol Obstet. , vol.167 , pp. 175-179
    • Scher, K.S.1
  • 130
    • 0030163126 scopus 로고    scopus 로고
    • Tetracyclines: Antibiotic action, uptake, and resistance mechanisms
    • Schnappinger D, Hillen W. Tetracyclines: antibiotic action, uptake, and resistance mechanisms. Arch Microbiol. 1996;165:359-69.
    • (1996) Arch Microbiol. , vol.165 , pp. 359-369
    • Schnappinger, D.1    Hillen, W.2
  • 132
    • 34548312103 scopus 로고    scopus 로고
    • Antibiotic resistance in an in vitro subgingival biofilm model
    • Sedlacek MJ, Walker C. Antibiotic resistance in an in vitro subgingival biofilm model. Oral Microbiol Immunol. 2007;22:333-9.
    • (2007) Oral Microbiol Immunol. , vol.22 , pp. 333-339
    • Sedlacek, M.J.1    Walker, C.2
  • 133
    • 0032913635 scopus 로고    scopus 로고
    • Macrolides and changes in the oral flora
    • Sefton AM. Macrolides and changes in the oral flora. Inter J Antimicrob Agents. 1999;11:S23-9;S31-2.
    • (1999) Inter J Antimicrob Agents. , vol.11
    • Sefton, A.M.1
  • 134
    • 38149049802 scopus 로고    scopus 로고
    • Antibiotics and chemoprophylaxis
    • Seymour RA, Hogg SD. Antibiotics and chemoprophylaxis. Periodontol 2000. 2008;46:80-108.
    • (2008) Periodontol 2000. , vol.46 , pp. 80-108
    • Seymour, R.A.1    Hogg, S.D.2
  • 135
    • 17444415301 scopus 로고    scopus 로고
    • Antibacterial resistance: Current problems and possible solutions
    • Sharma R, Sharma CL, Kapoor B. Antibacterial resistance: current problems and possible solutions. Indian J Med Sci. 2005;59:120-9.
    • (2005) Indian J Med Sci. , vol.59 , pp. 120-129
    • Sharma, R.1    Sharma, C.L.2    Kapoor, B.3
  • 136
    • 50549155848 scopus 로고
    • Metronidazole in acute ulceration gingivitis
    • Shinn D. Metronidazole in acute ulceration gingivitis. Lancet. 1962;1:1191.
    • (1962) Lancet. , vol.1 , pp. 1191
    • Shinn, D.1
  • 137
    • 0024522893 scopus 로고
    • Cloning and characterization of a Bacteroides conjugal tetracyclineerythromycin resistance element by using a shuttle cosmid vector
    • Shoemaker NB, Barber RD, Salyers AA. Cloning and characterization of a Bacteroides conjugal tetracyclineerythromycin resistance element by using a shuttle cosmid vector. J Bacteriol. 1989;171:1294-302.
    • (1989) J Bacteriol. , vol.171 , pp. 1294-1302
    • Shoemaker, N.B.1    Barber, R.D.2    Salyers, A.A.3
  • 138
    • 80051781995 scopus 로고    scopus 로고
    • Clinical and microbiological benefits of metronidazole alone or with amoxicillin as adjuncts in the treatment of chronic periodontitis: A randomized placebo-controlled clinical trial
    • Silva MP, Feres M, Siroto TA, Soares GM, Mendes JAV, Faveri M, et al. Clinical and microbiological benefits of metronidazole alone or with amoxicillin as adjuncts in the treatment of chronic periodontitis: a randomized placebo-controlled clinical trial. J Clin Periodontol. 2011;38:828-37.
    • (2011) J Clin Periodontol. , vol.38 , pp. 828-837
    • Silva, M.P.1    Feres, M.2    Siroto, T.A.3    Soares, G.M.4    Mendes, J.A.V.5    Faveri, M.6    et al7
  • 139
    • 0036359947 scopus 로고    scopus 로고
    • Dental biofi{ligature}lms: Diffi{ligature}cult therapeutic targets
    • Socransky SS, Haffajee AD. Dental biofi{ligature}lms: diffi{ligature}cult therapeutic targets. Periodontol 2000. 2002;28:12-55.
    • (2002) Periodontol 2000. , vol.28 , pp. 12-55
    • Socransky, S.S.1    Haffajee, A.D.2
  • 140
    • 31544435513 scopus 로고    scopus 로고
    • Molecular investigation of genetic elements contributing to metronidazole resistance in Bacteroides strain
    • Sóki J, Gal M, Brazier JS, Rotimi VO, Urbán E, Nagy E, et al. Molecular investigation of genetic elements contributing to metronidazole resistance in Bacteroides strain. J Antimicrob Chemother. 2006;57:212-20.
    • (2006) J Antimicrob Chemother. , vol.57 , pp. 212-220
    • Sóki, J.1    Gal, M.2    Brazier, J.S.3    Rotimi, V.O.4    Urbán, E.5    Nagy, E.6    et al7
  • 141
    • 0030604372 scopus 로고    scopus 로고
    • Consensus conference. Medical treatment of peptic ulcer disease. Practice guidelines. Practice Parameters Committee of the American College of Gastroenterology
    • Soll AH. Consensus conference. Medical treatment of peptic ulcer disease. Practice guidelines. Practice Parameters Committee of the American College of Gastroenterology. JAMA. 1996;275:622-9.
    • (1996) JAMA. , vol.275 , pp. 622-629
    • Soll, A.H.1
  • 142
    • 0026768854 scopus 로고
    • Bacterial resistance to tetracycline: Mechanisms, transfer, and clinical significance
    • Speer BS, Shoemaker NB, Salyers AA. Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance. Clin Microbiol Rev. 1992;5:387-99.
    • (1992) Clin Microbiol Rev. , vol.5 , pp. 387-399
    • Speer, B.S.1    Shoemaker, N.B.2    Salyers, A.A.3
  • 143
    • 0019326846 scopus 로고
    • Biochemical and genetical approaches to the mechanism of action of penicillin
    • Spratt BG. Biochemical and genetical approaches to the mechanism of action of penicillin. Philos Trans R Soc Lond B Biol Sci. 1980;289:273-83.
    • (1980) Philos Trans R Soc Lond B Biol Sci. , vol.289 , pp. 273-283
    • Spratt, B.G.1
  • 144
    • 0017949884 scopus 로고
    • The mechanism of action of penicillin
    • Spratt BG. The mechanism of action of penicillin. Sci Prog. 1978;65:101-28.
    • (1978) Sci Prog. , vol.65 , pp. 101-128
    • Spratt, B.G.1
  • 145
    • 0028420272 scopus 로고
    • Resistance to antibiotics mediated by target alterations
    • Spratt BG. Resistance to antibiotics mediated by target alterations. Science. 1994;264:388-93.
    • (1994) Science. , vol.264 , pp. 388-393
    • Spratt, B.G.1
  • 146
    • 0027303336 scopus 로고
    • Antimicrobial properties of human dentin impregnated with tetracycline HCl or chlorhexidine. An in vitro study
    • Stabholz A, Kettering J, Aprecio R, Zimmerman G, Baker PJ, Wikesjö UM. Antimicrobial properties of human dentin impregnated with tetracycline HCl or chlorhexidine. An in vitro study. J Clin Periodontal. 1993;20:557-62.
    • (1993) J Clin Periodontal. , vol.20 , pp. 557-562
    • Stabholz, A.1    Kettering, J.2    Aprecio, R.3    Zimmerman, G.4    Baker, P.J.5    Wikesjö, U.M.6
  • 147
    • 0029987015 scopus 로고    scopus 로고
    • Triple therapy with sucralfate, amoxicillin and metronidazole for healing duodenal ulcer and eradicating Helicobacter pylori infection
    • Stupnicki T, Taufer M, Denk H, Ratschek M, Spath P, Graf K. Triple therapy with sucralfate, amoxicillin and metronidazole for healing duodenal ulcer and eradicating Helicobacter pylori infection. Aliment Pharmacol Ther. 1996;10:193-7.
    • (1996) Aliment Pharmacol Ther. , vol.10 , pp. 193-197
    • Stupnicki, T.1    Taufer, M.2    Denk, H.3    Ratschek, M.4    Spath, P.5    Graf, K.6
  • 148
    • 0005114054 scopus 로고
    • Inhibition of aminoacyl tRNA binding to ribosomes by tetracycline
    • Suarez G, Nathans D. Inhibition of aminoacyl tRNA binding to ribosomes by tetracycline. Biochem Biophys Res Commun. 1965;18:743.
    • (1965) Biochem Biophys Res Commun. , vol.18 , pp. 743
    • Suarez, G.1    Nathans, D.2
  • 149
    • 0017149066 scopus 로고
    • Susceptibility of anaerobic bacteria to 23 antimicrobial agents
    • Sutter VL, Finegold SM. Susceptibility of anaerobic bacteria to 23 antimicrobial agents. Antimicrob Agents Chemother. 1976;10:736-52.
    • (1976) Antimicrob Agents Chemother. , vol.10 , pp. 736-752
    • Sutter, V.L.1    Finegold, S.M.2
  • 150
    • 0020645262 scopus 로고
    • Antimicrobial susceptibilities of bacteria associated with periodontal disease
    • Sutter VL, Jones MJ, Ghoneim AT. Antimicrobial susceptibilities of bacteria associated with periodontal disease. Antimicrob Agents Chemother. 1983;23:483-6.
    • (1983) Antimicrob Agents Chemother. , vol.23 , pp. 483-486
    • Sutter, V.L.1    Jones, M.J.2    Ghoneim, A.T.3
  • 153
    • 0033635978 scopus 로고    scopus 로고
    • TetZ, a new tetracycline resistance determinant discovered in gram-positive bacteria, shows high homology to gram-negative regulated efflux systems
    • Tauch A, Pühler A, Kalinowski J, Thierbach G. TetZ, a new tetracycline resistance determinant discovered in gram-positive bacteria, shows high homology to gram-negative regulated efflux systems. Plasmid. 2000;44:285-91.
    • (2000) Plasmid. , vol.44 , pp. 285-291
    • Tauch, A.1    Pühler, A.2    Kalinowski, J.3    Thierbach, G.4
  • 154
    • 0029033698 scopus 로고
    • Plasmids pIP419 and pIP421 from Bacteroides: 5-nitroimidazole resistance genes and their upstream insertion sequence elements
    • Trinh S, Haggoud A, Reysset G, Sebald M. Plasmids pIP419 and pIP421 from Bacteroides: 5-nitroimidazole resistance genes and their upstream insertion sequence elements. Microbiology. 1995;141:927-35.
    • (1995) Microbiology. , vol.141 , pp. 927-935
    • Trinh, S.1    Haggoud, A.2    Reysset, G.3    Sebald, M.4
  • 155
    • 0030912159 scopus 로고    scopus 로고
    • Identification and DNA sequence of the mobilization region of the 5-nitroimidazole resistance plasmid pIP421 from Bacteroides fragilis
    • Trinh S, Reysset G. Identification and DNA sequence of the mobilization region of the 5-nitroimidazole resistance plasmid pIP421 from Bacteroides fragilis. J Bacteriol. 1997;179:4071-4.
    • (1997) J Bacteriol. , vol.179 , pp. 4071-4074
    • Trinh, S.1    Reysset, G.2
  • 156
    • 0021835799 scopus 로고
    • Transmembrane permeability channels across the outer membrane of Haemophilus influenza type b
    • Vachon V, Lyew DJ, Coulton JW. Transmembrane permeability channels across the outer membrane of Haemophilus influenza type b. J Bacteriol. 1985;162:918-24.
    • (1985) J Bacteriol. , vol.162 , pp. 918-924
    • Vachon, V.1    Lyew, D.J.2    Coulton, J.W.3
  • 157
    • 22444439934 scopus 로고    scopus 로고
    • Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in The Netherlands and Spain
    • Van Winkelhoff AJ, Herrera D, Oteo A, Sanz M. Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in The Netherlands and Spain. J Clin Periodontol. 2005;32:891-8.
    • (2005) J Clin Periodontol. , vol.32 , pp. 891-898
    • van Winkelhoff, A.J.1    Herrera, D.2    Oteo, A.3    Sanz, M.4
  • 160
    • 0026543688 scopus 로고
    • Microbiological and clinical results of metronidazole plus amoxicillin therapy in Actinobacillus actinomycetemcomitans associated periodontitis
    • Van Winkelhoff AJ, Tijhof CJ, De Graaff J. Microbiological and clinical results of metronidazole plus amoxicillin therapy in Actinobacillus actinomycetemcomitans associated periodontitis. J Periodontol. 1992;63:52-7.
    • (1992) J Periodontol. , vol.63 , pp. 52-57
    • van Winkelhoff, A.J.1    Tijhof, C.J.2    de Graaff, J.3
  • 163
    • 0030072489 scopus 로고    scopus 로고
    • The acquisition of antimicrobial resistance in the periodontal microflora
    • Walker CB. The acquisition of antimicrobial resistance in the periodontal microflora. Periodontol 2000. 1996;10:79-88.
    • (1996) Periodontol 2000. , vol.10 , pp. 79-88
    • Walker, C.B.1
  • 164
    • 0030072461 scopus 로고    scopus 로고
    • Selected antimicrobial agents: Mechanisms of action, side effects and drug interactions
    • Walker CB. Selected antimicrobial agents: mechanisms of action, side effects and drug interactions. Periodontol 2000. 1996;10:12-28.
    • (1996) Periodontol 2000. , vol.10 , pp. 12-28
    • Walker, C.B.1
  • 165
    • 6044259000 scopus 로고    scopus 로고
    • Chemotherapeutics: Antibiotics and other antimicrobials
    • Walker CB, Karpinia K, Baehni P. Chemotherapeutics: antibiotics and other antimicrobials. Periodontol 2000. 2004;36:146-65.
    • (2004) Periodontol 2000. , vol.36 , pp. 146-165
    • Walker, C.B.1    Karpinia, K.2    Baehni, P.3
  • 166
    • 0345839252 scopus 로고    scopus 로고
    • Where will new antibiotics come from
    • Walsh C. Where will new antibiotics come from? Nat Rev Microbiol. 2003;1:65-70.
    • (2003) Nat Rev Microbiol. , vol.1 , pp. 65-70
    • Walsh, C.1
  • 168
    • 0018325052 scopus 로고
    • Subgingival microflora of periodontal patients on tetracycline therapy
    • Williams BL, Osterberg SK, Jorgensen J. Subgingival microflora of periodontal patients on tetracycline therapy. J Clin Periodontol. 1979;6:210-21.
    • (1979) J Clin Periodontol. , vol.6 , pp. 210-221
    • Williams, B.L.1    Osterberg, S.K.2    Jorgensen, J.3
  • 169
    • 0019224628 scopus 로고
    • The mechanism of action of penicillin. Penicillin acylates the active site of Bacillus stearothermophilus D-alanine carboxypeptidase
    • Yocum RR, Rasmussen JR, Strominger JL. The mechanism of action of penicillin. Penicillin acylates the active site of Bacillus stearothermophilus D-alanine carboxypeptidase. J Biol Chem. 1980;255:3977-86.
    • (1980) J Biol Chem. , vol.255 , pp. 3977-3986
    • Yocum, R.R.1    Rasmussen, J.R.2    Strominger, J.L.3
  • 170
    • 33644674742 scopus 로고    scopus 로고
    • Ribosomal crystallography: Peptide bond formation, chaperone assistance and antibiotics activity
    • Yonath A. Ribosomal crystallography: peptide bond formation, chaperone assistance and antibiotics activity. Mol Cells. 2005;20:1-16.
    • (2005) Mol Cells. , vol.20 , pp. 1-16
    • Yonath, A.1
  • 171
    • 0023771761 scopus 로고
    • Occurrence of the Campylobacter resistance gene tetO in Enterococcus and Streptococcus spp
    • Zihao R, Papadopoulou B, Courvalin P. Occurrence of the Campylobacter resistance gene tetO in Enterococcus and Streptococcus spp. Antimicrob Agents Chemother. 1988;32:1793-6.
    • (1988) Antimicrob Agents Chemother. , vol.32 , pp. 1793-1796
    • Zihao, R.1    Papadopoulou, B.2    Courvalin, P.3
  • 172
    • 79958801909 scopus 로고    scopus 로고
    • Review of macrolides (azithromycin, clarithromycin), ketolids (telithromycin) and glycylcyclines (tigecycline)
    • Zuckerman JM, Qamar F, Bono BR. Review of macrolides (azithromycin, clarithromycin), ketolids (telithromycin) and glycylcyclines (tigecycline). Med Clin North Am. 2011;95;761-91.
    • (2011) Med Clin North Am. , vol.95 , pp. 761-791
    • Zuckerman, J.M.1    Qamar, F.2    Bono, B.R.3


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