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Volumn 37, Issue 4, 2010, Pages 353-365

Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis

Author keywords

Dental plaque; Generalized aggressive periodontitis; Periodontal disease; Scaling and root planing

Indexed keywords

AMOXICILLIN; ANTIINFECTIVE AGENT; BACTERIAL DNA; METRONIDAZOLE;

EID: 77949769804     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2010.01538.x     Document Type: Article
Times cited : (134)

References (49)
  • 1
    • 0031254282 scopus 로고    scopus 로고
    • Putative periodontal pathogens in subgingival plaque of young adults with and without early-onset periodontitis
    • Albandar, J. M., Brown, L. J. Loe, H. (1997) Putative periodontal pathogens in subgingival plaque of young adults with and without early-onset periodontitis. Journal of Periodontology 68, 973 9781.
    • (1997) Journal of Periodontology , vol.68 , pp. 973-9781
    • Albandar, J.M.1    Brown, L.J.2    Loe, H.3
  • 3
    • 0033288546 scopus 로고    scopus 로고
    • Development of a classification and conditions
    • Armitage, G. C. (1999) Development of a classification and conditions. Annals of Periodontology 4, 1 6.
    • (1999) Annals of Periodontology , vol.4 , pp. 1-6
    • Armitage, G.C.1
  • 4
    • 0032060740 scopus 로고    scopus 로고
    • The use of metronidazole and amoxicillin in the treatment of advanced periodontal disease. A prospective, controlled clinical trial
    • Berglundh, T., Krok, L., Liljenberg, B., Westfelt, E., Serino, G. Lindhe, J. (1998) The use of metronidazole and amoxicillin in the treatment of advanced periodontal disease. A prospective, controlled clinical trial. Journal of Clinical Periodontology 25, 354 362.
    • (1998) Journal of Clinical Periodontology , vol.25 , pp. 354-362
    • Berglundh, T.1    Krok, L.2    Liljenberg, B.3    Westfelt, E.4    Serino, G.5    Lindhe, J.6
  • 5
    • 17644401680 scopus 로고    scopus 로고
    • Scaling and root planning, systemic metronidazole and professional plaque removal in the treatment of chronic periodontitis in a Brazilian population II - Microbiological results
    • Carvalho, L. H., D'Avila, G. B., Leao, A., Goncalves, C., Haffajee, A. D., Socransky, S. S. Feres, M. (2005) Scaling and root planning, systemic metronidazole and professional plaque removal in the treatment of chronic periodontitis in a Brazilian population II - microbiological results. Journal of Clinical Periodontology 32, 406 411.
    • (2005) Journal of Clinical Periodontology , vol.32 , pp. 406-411
    • Carvalho, L.H.1    D'Avila, G.B.2    Leao, A.3    Goncalves, C.4    Haffajee, A.D.5    Socransky, S.S.6    Feres, M.7
  • 6
    • 67650045503 scopus 로고    scopus 로고
    • Dimini- shed treatment response of periodontally diseased patients infected with the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans
    • Cortelli, S. C., Costa, F. O., Kawai, T., Aquino, D. R., Franco, G. C., Ohara, K., Roman-Torres, C. V. Cortelli, J. R. (2009) Dimini- shed treatment response of periodontally diseased patients infected with the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans. Journal of Clinical microbiology 47, 2018 2025.
    • (2009) Journal of Clinical Microbiology , vol.47 , pp. 2018-2025
    • Cortelli, S.C.1    Costa, F.O.2    Kawai, T.3    Aquino, D.R.4    Franco, G.C.5    Ohara, K.6    Roman-Torres, C.V.7    Cortelli, J.R.8
  • 8
    • 33749431376 scopus 로고    scopus 로고
    • Scaling and root planning and chlorhexidine mouth rinses in the treatment of chronic periodontitis: A randomized, placebo-controlled clinical trial
    • Faveri, M., Gursky, L. C., Feres, M., Shibli, J. A., Salvador, S. L. Figueiredo, L. C. (2006) Scaling and root planning and chlorhexidine mouth rinses in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. Journal of Clinical Periodontology 33, 819 828.
    • (2006) Journal of Clinical Periodontology , vol.33 , pp. 819-828
    • Faveri, M.1    Gursky, L.C.2    Feres, M.3    Shibli, J.A.4    Salvador, S.L.5    Figueiredo, L.C.6
  • 10
    • 70349141302 scopus 로고    scopus 로고
    • Clinical and microbiological benefits of strict supragingival plaque control as part of the active phase of periodontal therapy
    • Feres, M, Gursky, L. C., Faveri, M., Ota- Tsuzuki, C. Figueiredo, L. C. (2009) Clinical and microbiological benefits of strict supragingival plaque control as part of the active phase of periodontal therapy. Journal of Clinical Periodontology 36, 857 867.
    • (2009) Journal of Clinical Periodontology , vol.36 , pp. 857-867
    • Feres, M.1    Gursky, L.C.2    Faveri, M.3    Ota- Tsuzuki, C.4    Figueiredo, L.C.5
  • 11
    • 37249071345 scopus 로고    scopus 로고
    • Aggregatibacter actinomycetemcomitans and its relationship to initiation of localized aggressive periodontitis: Longitudinal cohort study of initially healthy adolescents
    • Fine, D. H., Markowitz, K., Furgang, D., Fairlie, K., Ferrandiz, J., Nasri, C., McKiernan, M. Gunsolley, J. (2007) Aggregatibacter actinomycetemcomitans and its relationship to initiation of localized aggressive periodontitis: longitudinal cohort study of initially healthy adolescents. Journal of Clinical Microbiology 45, 3859 3869.
    • (2007) Journal of Clinical Microbiology , vol.45 , pp. 3859-3869
    • Fine, D.H.1    Markowitz, K.2    Furgang, D.3    Fairlie, K.4    Ferrandiz, J.5    Nasri, C.6    McKiernan, M.7    Gunsolley, J.8
  • 12
    • 17444391294 scopus 로고    scopus 로고
    • Prevalence of periodontopathic bacteria in aggressive periodontitis patients in a Chilean population
    • Gajardo, M., Silva, N., Gomez, L., Leon, R., Parra, B., Contreras, A. Gamonal, J. (2005) Prevalence of periodontopathic bacteria in aggressive periodontitis patients in a Chilean population. Journal of Periodontology 76, 289 294.
    • (2005) Journal of Periodontology , vol.76 , pp. 289-294
    • Gajardo, M.1    Silva, N.2    Gomez, L.3    Leon, R.4    Parra, B.5    Contreras, A.6    Gamonal, J.7
  • 13
    • 25844497516 scopus 로고    scopus 로고
    • Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: A randomized placebo-controlled clinical trial
    • Guerrero, A., Griffiths, G. S., Nibali, L., Suvan, J., Moles, D. R., Laurell, L. Tonetti, M. S. (2005) Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: a randomized placebo-controlled clinical trial. Journal of Clinical Periodontology 32, 1096 1107.
    • (2005) Journal of Clinical Periodontology , vol.32 , pp. 1096-1107
    • Guerrero, A.1    Griffiths, G.S.2    Nibali, L.3    Suvan, J.4    Moles, D.R.5    Laurell, L.6    Tonetti, M.S.7
  • 15
    • 13244298315 scopus 로고    scopus 로고
    • Differences in the subgingival microbiota of Swedish and USA subjects who were periodontally healthy or exhibited minimal periodontal disease
    • Haffajee, A. D., Japlit, M., Bogren, A., Kent, R. L. Jr., Goodson, J. M. Socransky, S. S. (2005) Differences in the subgingival microbiota of Swedish and USA subjects who were periodontally healthy or exhibited minimal periodontal disease. Journal of Clinical Periodontology 32, 33 39.
    • (2005) Journal of Clinical Periodontology , vol.32 , pp. 33-39
    • Haffajee, A.D.1    Japlit, M.2    Bogren, A.3    Kent, Jr.R.L.4    Goodson, J.M.5    Socransky, S.S.6
  • 16
    • 39049173083 scopus 로고    scopus 로고
    • Microbiological changes associated with four different periodontal therapies for the treatment of chronic periodontitis
    • Haffajee, A. D., Patel, M. Socransky, S. S. (2008) Microbiological changes associated with four different periodontal therapies for the treatment of chronic periodontitis. Oral Microbiology and Immunology 23, 112 118.
    • (2008) Oral Microbiology and Immunology , vol.23 , pp. 112-118
    • Haffajee, A.D.1    Patel, M.2    Socransky, S.S.3
  • 17
    • 0021506680 scopus 로고
    • Clinical, microbiological and immunological features associated with the treatment of active periodontosis lesions
    • Haffajee, A. D., Socransky, S. S., Ebersole, J. L. Smith, D. J. (1984) Clinical, microbiological and immunological features associated with the treatment of active periodontosis lesions. Journal of Clinical Periodontology 11, 600 618.
    • (1984) Journal of Clinical Periodontology , vol.11 , pp. 600-618
    • Haffajee, A.D.1    Socransky, S.S.2    Ebersole, J.L.3    Smith, D.J.4
  • 19
    • 38149103763 scopus 로고    scopus 로고
    • Risk of aggressive periodontitis in adolescent carriers of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans in Morocco: A prospective longitudinal cohort study
    • Haubek, D., Ennibi, O. K., Poulsen, K., Vaeth, M., Poulsen, S. Kilian, M. (2008) Risk of aggressive periodontitis in adolescent carriers of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans in Morocco: a prospective longitudinal cohort study. Lancet 371, 237 242.
    • (2008) Lancet , vol.371 , pp. 237-242
    • Haubek, D.1    Ennibi, O.K.2    Poulsen, K.3    Vaeth, M.4    Poulsen, S.5    Kilian, M.6
  • 20
    • 0037928810 scopus 로고    scopus 로고
    • A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients
    • Herrera, D., Sanz, M., Jepsen, S., Needleman, I. Roldan, S. (2002) A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients. Journal of Clinical Periodontology 29, 136 159.
    • (2002) Journal of Clinical Periodontology , vol.29 , pp. 136-159
    • Herrera, D.1    Sanz, M.2    Jepsen, S.3    Needleman, I.4    Roldan, S.5
  • 21
    • 34548583390 scopus 로고    scopus 로고
    • Controlled-delivery chlorhexidine chip versus amoxicillin/metronidazole as adjunctive antimicrobial therapy for generalized aggressive periodontitis: A randomized controlled clinical trial
    • Kaner, D., Bernimoulin, J. P., Hopfenmuller, W., Kleber, B. M. Friedmann, A. (2007) Controlled-delivery chlorhexidine chip versus amoxicillin/ metronidazole as adjunctive antimicrobial therapy for generalized aggressive periodontitis: a randomized controlled clinical trial. Journal of Clinical Periodontology 34, 880 891.
    • (2007) Journal of Clinical Periodontology , vol.34 , pp. 880-891
    • Kaner, D.1    Bernimoulin, J.P.2    Hopfenmuller, W.3    Kleber, B.M.4    Friedmann, A.5
  • 24
    • 54449087992 scopus 로고    scopus 로고
    • The use of 2 antibiotic regimens in aggressive periodontitis: Comparison of changes in clinical parameters and gingival crevicular fluid biomarkers
    • Machtei, E. E. Younis, M. N. (2008) The use of 2 antibiotic regimens in aggressive periodontitis: comparison of changes in clinical parameters and gingival crevicular fluid biomarkers. Quintessence International 39, 811 819.
    • (2008) Quintessence International , vol.39 , pp. 811-819
    • MacHtei, E.E.1    Younis, M.N.2
  • 26
    • 51749102672 scopus 로고    scopus 로고
    • Clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: A randomized placebo-controlled study
    • Matarazzo, F., Figueiredo, L. C., Cruz, S. E., Faveri, M. Feres, M. (2008) Clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: a randomized placebo-controlled study. Journal of Clinical Periodontology 35, 885 896.
    • (2008) Journal of Clinical Periodontology , vol.35 , pp. 885-896
    • Matarazzo, F.1    Figueiredo, L.C.2    Cruz, S.E.3    Faveri, M.4    Feres, M.5
  • 28
    • 0033629059 scopus 로고    scopus 로고
    • Persistence patterns of Porphyromonas gingivalis, Prevotella intermedia/nigrescens, and Actinobacillus actinomyetemcomitans after mechanical therapy of periodontal disease
    • Mombelli, A., Schmid, B., Rutar, A. Lang, N. P. (2000) Persistence patterns of Porphyromonas gingivalis, Prevotella intermedia/nigrescens, and Actinobacillus actinomyetemcomitans after mechanical therapy of periodontal disease. Journal of Periodontology 71, 14 21.
    • (2000) Journal of Periodontology , vol.71 , pp. 14-21
    • Mombelli, A.1    Schmid, B.2    Rutar, A.3    Lang, N.P.4
  • 29
    • 0034251637 scopus 로고    scopus 로고
    • Prevalence of periodontal pathogens in localized and generalized forms of early-onset periodontitis
    • Mullally, B. H., Dace, B., Shelburne, C. E., Wolff, L. F. Coulter, W. A. (2000) Prevalence of periodontal pathogens in localized and generalized forms of early-onset periodontitis. Journal of Periodontal Research 35, 232 241.
    • (2000) Journal of Periodontal Research , vol.35 , pp. 232-241
    • Mullally, B.H.1    Dace, B.2    Shelburne, C.E.3    Wolff, L.F.4    Coulter, W.A.5
  • 30
    • 0026464889 scopus 로고
    • In vitro susceptibilities of Actinobacillus actinomycetemcomitans to a number of antimicrobial combinations
    • Pavicić, M. J., van Winkelhoff, A. J. de Graaff, J. (1992) In vitro susceptibilities of Actinobacillus actinomycetemcomitans to a number of antimicrobial combinations. Antimicrobial Agents and Chemotherapy 36, 2634 2638.
    • (1992) Antimicrobial Agents and Chemotherapy , vol.36 , pp. 2634-2638
    • Pavicić, M.J.1    Van Winkelhoff, A.J.2    De Graaff, J.3
  • 32
    • 0027621545 scopus 로고
    • Classification of periodontal diseases
    • Ranney, R. R. (1993) Classification of periodontal diseases. Periodontology 2000 2, 13 25.
    • (1993) Periodontology 2000 , vol.2 , pp. 13-25
    • Ranney, R.R.1
  • 33
    • 0038266225 scopus 로고    scopus 로고
    • A systematic review on the use of residual probing depth, bleeding on probing and furcation status following initial periodontal therapy to predict further attachment and tooth loss
    • Renvert, S. Persson, G. R. (2002) A systematic review on the use of residual probing depth, bleeding on probing and furcation status following initial periodontal therapy to predict further attachment and tooth loss. Journal of Clinical Periodontology 29 (Suppl 3), 82 89.
    • (2002) Journal of Clinical Periodontology , vol.29 , Issue.SUPPL 3 , pp. 82-89
    • Renvert, S.1    Persson, G.R.2
  • 34
    • 0025345761 scopus 로고
    • Effect of root debridement on the elimination of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis from periodontal pockets
    • Renvert, S., Wikström, M., Dahlén, G., Slots, J. Egelberg, J. (1990) Effect of root debridement on the elimination of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis from periodontal pockets. Journal of Clinical Periodontology 17, 345 350.
    • (1990) Journal of Clinical Periodontology , vol.17 , pp. 345-350
    • Renvert, S.1    Wikström, M.2    Dahlén, G.3    Slots, J.4    Egelberg, J.5
  • 35
    • 0017284357 scopus 로고
    • The predominant cultivable organisms in juvenile periodontitis. Scandinavian
    • Slots, J. (1976) The predominant cultivable organisms in juvenile periodontitis. Scandinavian. Journal of Dental Research 84, 1 10.
    • (1976) Journal of Dental Research , vol.84 , pp. 1-10
    • Slots, J.1
  • 39
    • 0033144211 scopus 로고    scopus 로고
    • Effect of initial periodontal therapy on the frequency of detecting Bacteroides forsythus, Porphyromonas gingivalis, and Actinobacillus actinomycetemcomitans
    • Takamatsu, N., Yano, K., He, T., Umeda, M. Ishikawa, I. (1999) Effect of initial periodontal therapy on the frequency of detecting Bacteroides forsythus, Porphyromonas gingivalis, and Actinobacillus actinomycetemcomitans. Journal of Periodontology 70, 574 580.
    • (1999) Journal of Periodontology , vol.70 , pp. 574-580
    • Takamatsu, N.1    Yano, K.2    He, T.3    Umeda, M.4    Ishikawa, I.5
  • 43
    • 22444439934 scopus 로고    scopus 로고
    • Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in the Netherlands and Spain
    • van Winkelhoff, A. J., Herrera, D., Oteo, A. Sanz, M. (2005) Antimicrobial profiles of periodontal pathogens isolated from periodontitis patients in the Netherlands and Spain. Journal of Clinical Periodontology 32, 893 898.
    • (2005) Journal of Clinical Periodontology , vol.32 , pp. 893-898
    • Van Winkelhoff, A.J.1    Herrera, D.2    Oteo, A.3    Sanz, M.4
  • 46
    • 0032197013 scopus 로고    scopus 로고
    • Additional clinical and microbiological effects of amoxicillin and metronidazole after initial periodontal therapy
    • Winkel, E. G., van Winkelhoff, A. J. van der Velden, U. (1998) Additional clinical and microbiological effects of amoxicillin and metronidazole after initial periodontal therapy. Journal of Clinical Periodontology 25, 857 864.
    • (1998) Journal of Clinical Periodontology , vol.25 , pp. 857-864
    • Winkel, E.G.1    Van Winkelhoff, A.J.2    Van Der Velden, U.3
  • 49
    • 2442536921 scopus 로고    scopus 로고
    • Relationship of Actinobacillus actinomycetemcomitans serotype b to aggressive periodontitis: Frequency in pure cultured isolates
    • Yang, H. W., Asikainen, S., Dogan, B., Suda, R. Lai, C. H. (2004) Relationship of Actinobacillus actinomycetemcomitans serotype b to aggressive periodontitis: frequency in pure cultured isolates. Journal of Periodontology 75, 592 599.
    • (2004) Journal of Periodontology , vol.75 , pp. 592-599
    • Yang, H.W.1    Asikainen, S.2    Dogan, B.3    Suda, R.4    Lai, C.H.5


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