Detection and prevalence of the tetracycline resistance determinant Tet Q in the microbiota associated with adult periodontitis

Oral Microbiology and Immunology

Volumn 11, Issue 4, 1996, Pages 282-288

  Lacroix, J M ^a,b   Walker, C B ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Gene; Methods; Microbiology; Periodontitis; Polymerase chain reaction; Resistance; tet(Q); Tetracycline

Indexed keywords

EID: 0030206368     PISSN: 09020055     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-302X.1996.tb00182.x     Document Type: Article

References (41)

1. Bailey WR, Scott EG. Diagnostic microbiology. 4th edn. St. Louis. Mosby, 1974.
2. Burdett V. Streptococcal tetracycline resistance mediated at the level of protein synthesis. J Bacteriol 1986: 165: 564-569.
3. Burdett V. Purification and characterization of Tet(M), a protein that renders ribosomes resistant to tetracycline. J Biol Chem 1991: 226: 2672-2877.
4. Charpentier E, Gerbaud G, Courvalin P. Characterization of a new class of tetracycline-resisrtance gene tet(S) in Listeria monocytogenes BM4210 Gene 1993: 131: 27-34.
5. Chopra I, Hawkey PM, Hinton M. Tetracyclines, molecular and clinical aspects. J Antimicrob Chemother 1992: 29: 245-277.
6. Fletcher HM, Macrina FL. Molecular survey of clindamycin and tetracycline resistance determinant in Bacteroides species. Antimicrob Agents Chemother 1991: 35: 2415-2418.
7. Genco RJ. Antibiotics in the treatment of human periodontal diseases. J Periodontol 1981: 52: 545-558.
8. Gordon JM, Walker CB. Current status of systemic antibiotic usage in destructive periodontal disease. J Periodontol 1993: 64: 760-771.
9. Grunstein M, Hogness DS. Colony hybridizations: a method for the isolation of cloned DNAs that contain a specific gene. Proc Natl Acad Sci USA 1975: 72: 3961-3965.
10. Guiney DD, Hasegawa P. Transfer of conjugal elements in oral black-pigmented Bacteroides (Prevotella) spp. involves DNA rearrangements. J Bacteriol 1992: 174: 4853-4855.
11. Guiney DG, Bouic K. Detection of conjugal transfer system in oral, black-pigmented Bacteroides spp. J Bacteriol 1990: 172: 495-497.
12. Guiney DG, Hasegawa P, Bouic K, Matthews B. Genetic transfer systems in Bacteroides: cloning and mapping of the transferable tetracycline-resistance locus. Mol Microbiol 1989: 3: 1617-1623.
13. Haffajee AD, Dzink JL, Socransky SS. Effect of modified widman flap surgery and systemic tetracycline on the subgingival microbiota of periodontal lesions. J Clin Periodontol 1988: 15: 255-262.
14. Koch AL. Growth measurements. In: Gerhardt P, Murray RGE, Costilow RN et al., ed. Manual of methods for general microbiology. Washington, DC: Am Soc Microbiol, 1981: 179-207.
15. Kornman KS, Karl EH. The effect of long-term low-dose tetracycline therapy on the subgingival microflora in refractory adult periodontitis. J Periodontol 1982: 53: 604-610.
16. Kornman KS, Robertson PB. Clinical and microbiological evaluation of therapy for juvenile periodontitis. J Periodontol 1985: 56: 443-446.
17. Lacroix J-M, Walker CB. Detection and incidence of the Tet Q determinant in the periodontal microflora. 72nd General Session and Exhibition of the International Association for Dental Research. J Dent Res 1994: 73: 375 (abstr 2187).
18. Lacroix J-M, Walker CB. Detection and incidence of the tetracycline resistance determinant tet(M) in the microflora associated with adult periodontitis. J Periodontol 1995: 66: 102-108.
19. LeBlanc D, Lee LN, Titmas BM, Smith CJ, Tenover FC. Nucleotide sequence analysis of tetracycline resistance gene tetO from Streptotoccus mutans DL5. J Bacteriol 1988: 170: 3618-3626.
20. Lépine G, Lacroix J-M, Walker CB, Progulske-Fox A. Sequencing of a tet(Q) gene isolated from Bacteroides fragilis 1126. Antimicrob Agents Chemother 1993: 37: 2037-2041.
21. Lépine G, Progulske-Fox A. Isogenic mutations in two hemagglutinin genes of Porphyromonas gingivalis. 71st General Session and Exhibition of the International Association for Dental Research. J Dent Res 1993: 72: 118 (abstr 120).
22. Levy SB. Tetracycline resistance are widespread. ASM News 1988: 54: 418-421.
23. Lundström A, Johansson L-A, Hamp S-E. Effect of combined systemic antimicrobial therapy and mechanical plaque control in patients with recurrent periodontal disease. J Clin Periodontol 1984: 11: 321-330.
24. Marshall B, Tachibana C, Levy SB. Frequency of tetracycline resistance determinant classes among lactose-fermenting coliforms. Antimicrob Agents Chemother 1983: 24: 835-840.
25. McCulloch CAG, Birek P, Ovorall C, Aitken S, Lee W, Kulkarni G. Randomized controlled trial of doxycycline in prevention of recurrent periodontitis in high risk patients: antimicrobial activity and collagenase inhibition. J Clin Periodontol 1990: 17: 616-622.
26. Moore LVH, Moore WEC. Oribaculum catoniae gen nov., sp. nov ; Catonella morbi gen. nov., sp. nov.; Hallella seregens gen. nov., sp. nov.; Johnsonella ignava gen. nov, sp. nov.; and Dialister pneumosintes gen. nov., comb. nov., nom. rev., anaerobic gram-negative bacilli from the human gingival crevice. Int J Syst Bacteriol 1994: 44: 187-192.
27. Nikolich MP, Shoemaker NB, Salvers AA. A Bacteroides tetracycline resistance gene represent a new class of ribosome protection tetracycline resistance. Antimicrob Agents Chemother 1992: 36: 1005-1012.
28. Olsvik B, Olsen I, Tenover FC. The tet(Q) gene in bacteria isolated from patients with refractory periodontal disease. Oral Microbiol Immunol 1994: 9: 251-255.
29. Page RC, Altman LC, Ebersole JL et al. Rapidly progressive periodontitis. A distinct clinical condition. J Periodontol 1983: 54: 197-209.
30. Rams TE, Keyes PH, Wright WE, Howard SA. Long-term effects of microbiologically modulated periodontal therapy on advanced adult periodontitis. J Am Dent Assoc 1985: 111: 429-441.
31. Roberts MC, Brown BA, Steingrube VA, Richard J Jr. Genetic basis of tetracycline resistance in Moraxella (Branhamella) catarrhalis. Antimicrob Agents Chemother 1990: 34: 1816-1818.
32. Salyers AA, Speer BS, Shoemaker NB. New perspectives in tetracycline resistance. Mol Microbiol 1990: 4: 151-156.
33. Shoemaker N, Wang G-R, Salyers AA. Evidence for natural transfer of a tetracycline resistance gene between bacteria from the human colon and bacteria from the bovine rumen. Appl Environ Microbiol 1992: 58: 1313-1320.
34. Slots J, Mashimo P, Levine MJ, Genco RJ. Periodontal therapy in humans. I. Microbiological and clinical effects of a single course of periodontal scaling and root planning, and of adjunctive tetracycline therapy. J Periodentol 1979: 50: 495-509.
35. Speer BS, Bedzyk L, Salyers AA. Evidence that a novel tetracycline resistance gene found on two Bacteroides transposons encodes an NADP-requiring oxidoreductase. J Bacteriol 1991: 173: 176-183.
36. Speer BS, Salyers AA. Characterization of a novel tetracycline resistance that function only in aerobically grown Escherichia coli. J Bacteriol 1988: 170: 1423-1429.
37. Speer BS, Shoemaker NB, Saylers AA. Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance. Clin Microbiol Rev 1992: 5: 387-399.
38. Walker CB, Gordon JM, McQuilkin SJ, Niebloom TA, Socransky SS. Tetracycline: Levels achievable in gingival crevice fluid and in vino effect on subgingival organisms. II. Susceptibilities of periodontal bacteria. J Periodontol 1981: 52: 613-616.
39. Walker CB, Nielbloom TA, Socransky SS. Agar medium for use in susceptibility testing of bacteria from human periodontal pockets. Antimicrob. Agents Chemother 1979: 16: 452-457.
40. Walker CB, Pappas JD, Tyler KZ, Cohen S, Gordon JM. Antibiotic susceptibilities of periodontal bacteria. In vitro susceptibilities to eight antimicrobial agents. J Periodontol 1985: 56 (suppl): 67-74.
41. Wexler HM. Susceptibility testing of anerobic bacteria - the state of the art. Clin Infect Dis 1993: 16: S328-S333.