The protective effects of riluzole on manganese-induced disruption of glutamate transporters and glutamine synthetase in the cultured astrocytes

Biological Trace Element Research

Volumn 148, Issue 2, 2012, Pages 242-249

  Deng, Yu ^a   Xu, Zhaofa ^a   Xu, Bin ^a   Xu, Donghui ^a   Tian, Yawen ^a   Feng, Wanyu ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Glutamate transporter 1; Glutamate aspartate transporter; Glutamine synthetase; Manganese; Riluzole

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE AMMONIA LIGASE; GLUTAMATE TRANSPORTER; MANGANESE; MANGANESE CHLORIDE; MESSENGER RNA; RILUZOLE; VESICULAR GLUTAMATE TRANSPORTER 1;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; NEWBORN; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN TRANSPORT; RAT;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELLS, CULTURED; CHLORIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLUTAMATE-AMMONIA LIGASE; GLUTAMIC ACID; MANGANESE; MANGANESE COMPOUNDS; MANGANESE POISONING; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RILUZOLE; RNA, MESSENGER; SODIUM-POTASSIUM-EXCHANGING ATPASE; TOXICITY TESTS, CHRONIC;

EID: 84864681702     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9365-1     Document Type: Article

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