Receptor-mediated transcytosis: A mechanism for active extravascular transport of nanoparticles in solid tumors

Journal of Controlled Release

Volumn 161, Issue 3, 2012, Pages 959-966

  Lu, Wei ^a   Xiong, Chiyi ^a   Zhang, Rui ^a   Shi, Lifang ^b   Huang, Miao ^a   Zhang, Guodong ^a   Song, Shaoli ^a   Huang, Qian ^a   Liu, Gang Yu ^b   Li, Chun ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Agonists; Antagonists; Melanocortin type 1 receptor (MC1R); Nanoparticles; Transcytosis

Indexed keywords

ACTIVE TRANSPORT; AGONISTS; ANTAGONISTS; BIOLOGICAL BARRIER; CELL SURFACES; DELIVERY SYSTEMS; GOLD NANOSPHERES; LIGAND-RECEPTOR BINDING; MELANOCORTIN TYPE-1 RECEPTOR (MC1R); MELANOMA CELLS; NON-TARGETED; RECEPTOR-MEDIATED ENDOCYTOSIS; SOLID TUMORS; THERANOSTICS; TRANSCYTOSIS; TUMOR CELLS; TUMOR UPTAKE; TUMOR VESSELS;

CELL MEMBRANES; GOLD COATINGS; LIGANDS; MOLECULAR BIOLOGY; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

NANOPARTICLES;

COPPER 64; GOLD NANOPARTICLE; HORMONE RECEPTOR BLOCKING AGENT; MACROGOL; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN RECEPTOR AGONIST; MELANOCORTIN RECEPTOR ANTAGONIST; NANOSPHERE; PEGYLATED HOLLOW GOLD NANOSPHERE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL SURFACE; CONJUGATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG TUMOR LEVEL; DRUG UPTAKE; ENDOCYTOSIS; EXTRAVASCULAR FLUID; EXTRAVASCULAR SPACE; FEMALE; HORMONE RECEPTOR INTERACTION; INTERNALIZATION; LIGAND BINDING; MATERIAL COATING; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR; TRANSCYTOSIS; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VASCULARIZATION;

ANIMALS; FEMALE; GOLD; HEK293 CELLS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MICE, NUDE; NANOSPHERES; POLYETHYLENE GLYCOLS; RECEPTOR, MELANOCORTIN, TYPE 1; TRANSCYTOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84864605778     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.05.014     Document Type: Article

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