Analysis of the role of the integrin signaling pathway in hepatocytes during rat liver regeneration

Cellular and Molecular Biology Letters

Volumn 17, Issue 2, 2012, Pages 274-288

  Xu, Cunshuan ^a,b   Yang, Yanjie ^a,b   Yang, Junying ^b   Chen, Xiaoguang ^b   Wang, Gaiping ^b  

^a HENAN NORMAL UNIVERSITY   (China)

^b Key Laboratory for Cell Differentiation Regulation   (China)

Author keywords

Gene expression profile; Gene synergy value; Hepatocyte proliferation; Immunochemistry; Integrin signaling pathway; Liver regeneration; Partial hepatectomy; Rat; Rat Genome 230 2.0 array; RT PCR

Indexed keywords

INTEGRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE SYNERGY VALUE; GENETIC PARAMETERS; LIVER CELL; LIVER REGENERATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; BIOLOGY; DNA MICROARRAY; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; COMPUTATIONAL BIOLOGY; GENE EXPRESSION PROFILING; HEPATOCYTES; INTEGRINS; LIVER REGENERATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84864582837     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-012-0011-x     Document Type: Article

References (41)

1. Yokoyama, Y., Nagino, M. and Nimura, Y. Mechanisms of hepatic regeneration following portal vein embolization and partial hepatectomy: a review. World J. Surg. 31 (2007) 367-374.
2. Michalopoulos, G. K. Liver regeneration. J. Cell Physiol. 213 (2007) 286-300.
3. Vondran, F. W., Katenz, E., Schwartlander, R., Morgul, R. S., Haluk, M., Raschzok, N., Gong, X. B., Cheng, X. D., Kehr, D. and Sauer, I. M. Isolation of primary human hepatocytes after partial hepatectomy: criteria for identification of the most promising liver specimen. Artif. Organs32 (2008) 205-213.
4. Estes, M. D., Do J. and Ahn, C. H. On chip cell separator using magnetic bead-based enrichment and depletion of various surface markers. Biomed. Microdevices11 (2009) 509-515.
5. Xu, C. S., Chen, X. G., Chang, C. F., Wang, G. P., Wang, W. B. and Zhang, L. X. Transcriptome analysis of hepatocytes after partial hepatectomy in rats. Dev. Genes. Evol. 220 (2010) 263-274.
6. Hehlgans, S., Haase, M., and Cordes, N. Signalling via integrins: implications for cell survival and anticancer strategies. Biochim. Biophys. Acta. 1775 (2007) 163-180.
7. Donthamsetty, S., Bowen, W., Mars, W., Bhave, V., Luo, J. H., Wu, C., Hurd, J., Orr, A., Bell, A. and Michalopoulos, G. K. Liver-specific ablation of integrin-linked kinase in mice results in enhanced and prolonged cell proliferation and hepatomegaly after phenobarbital administration. Toxicol. Sci. 113 (2010) 358-366.
8. Mayoral, R., Fernández-Martínez, A., Roy, R., Boscá, L. and Martín-Sanz, P. Dispensability and dynamics of caveolin-1 during liver regeneration and in isolated hepatic cells. Hepatology46 (2007) 813-822.
9. Zouq, N. K., Keeble, J. A., Lindsay, J., Valentijn, A. J., Zhang, L., Mills, D., Turner, C. E., Streuli, C. H. and Gilmore, A. P. FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas. J. Cell Sci. 122 (2009) 357-367.
10. Tabe, Y., Jin, L., Tsutsumi-Ishii, Y., Xu, Y., McQueen, T., Priebe, W., Mills, G. B., Ohsaka, A., Nagaoka, I., Andreeff, M. and Konopleva, M. Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemiccells by bone marrow-derived stromal cells. Cancer Res. 67 (2007) 684-694.
11. Lemons, M. L. and Condic, M. L. Integrin signaling is integral to regeneration. Exp. Neurol. 209 (2008) 343-352.
12. Zhang, X., Li, C., Gao, H., Nabeka, H., Shimokawa, T., Wakisaka, H., Matsuda, S. and Kobayashi, N. Rho kinase inhibitors stimulate the migration of human cultured osteoblastic cells by regulating actmyosin activity. Cell. Mol. Biol. Lett. 16 (2011) 279-295.
13. Auriemma, C., Viscardi, M., Tafuri, S., Pavone, L. M., Capuano, F., Rinaldi, L., Della Morte, R., Iovane, G. and Staiano, N. Integrin receptors play a role in the integrin β-dependent entry of Listeria monocytogenes into host cells. Cell. Mol. Biol. Lett. 15 (2010) 496-506.
14. Brown, E. J. and Frazier, W. A. Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 11 (2001) 130-135.
15. Higgins, G. M. and Anderson, R. M. Experimental pathology of the liver: Restoration of the liver of the white rat following partial surgical removal. Arch. Pathol. 12 (1931) 186-202.
16. Grisham, J. W. Cell types in rat liver cultures: their identification and isolation. Mol. Cell. Biochem. 54 (2008) 23-33.
17. Qin, Y. and Tian, Y. P. A microarray gene analysis of peripheral whole blood in normal adult male ratsafter long-term GH gene therapy. Cell. Mol. Biol. Lett. 15 (2010) 177-195.
18. Twigger, S. N., Smith J., Zuniga-Meyer, A. and Bromberg, S. K. Exploring phenotypic data at the rat genome database. Curr. Protoc. Bioinformatics (2006) Chapter 1, Unit 1. 14.
19. Wang, J. Z., Du, Z., Payattakool, R., Yu, P. S. and Chen, C. F. A new method to measure the semantic similarity of GO terms. Bioinformatics23 (2007) 1274-1281.
20. Guo, W., Cai, C., Wang, C., Zhao, L., Wang, L. and Zhang, T. A preliminary analysis of genome structure and composition in Gossypium hirsutum. BMC Genomics9 (2008) 314.
21. Wang, G. P. and Xu, C. S. Reference gene selection for real-time RT-PCR in eight kinds of rat regenerating hepatic cells. Mol. Biotechnol. 46 (2010) 49-57.
22. Hynes, R. O. A reevaluation of integrins as regulators of angiogenesis. Nat. Med. 8 (2002) 918-921.
23. Katz, B. Z., Romer, L., Miyamoto, S., Volberg, T., Matsumoto, K., Cukierman, E., Geiger, B. and Yamada, K. M. Targeting membrane-localized focal adhesion kinase to focal adhesion: roles of tyrosinephosphorylation and SRC family kinases. J. Biol. Chem. 278 (2003) 29115-29120.
24. Lee, J. W. and Juliano, R. Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways. Mol. Cells17 (2004) 188-202.
25. Wang, W. B., Fan, J. M., Zhang, X. L., Xu, J. and Yao, W. Serial expression analysis of liver regeneration-related genes in rat regenerating liver. Mol. Biotechnol. 43 (2009) 221-231.
26. Tong, H. On a threshold model, pattern recognition and signal processing, In: NATO ASI series E: Applied Sc No. 29.(Chen, C. H. Ed.) Alphen aan den Rijn, The Netherland: Sijthoff & Noordhoff, 1978.
27. Eisen, M. B., Spellman, P. T., Brown, P. O. and Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Nat. Acad. Sci. USA95 (1998) 14863-14868.
28. Li, H., Chen, X. G, Zhang, F. C., Ma, J. and Xu, C. S. Expression patterns of the cell junction-associated genes during rat liver regeneration. J. Genet. Genomics34 (2007) 892-908.
29. Nguyen, L. N., Furuya, M. H., Wolfraim, L. A., Nguyen, A. P., Holdren, M. S., Campbell, J. S., Knight, B., Yeoh, G. C., Fausto, N. and Parks, W. T. Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation. Hepatology45 (2007) 31-41.
30. Fausto, N., Campbell, J. S. and Riehle, K. J. Liver regeneration. Hepatology43 (2006) S45-53.
31. Frank, P. G. and Lisanti, M. P. Caveolin-1 and liver regeneration: role in proliferation and lipogenesis. Cell Cycle6 (2007) 115-116.
32. Williams, T. M. and Listanti, M. P. Caveolin-1 in oncogeic transformation, cancer, and metastasis. Am. J. Physiol. Cell Physiol. 288 (2005) C494-506.
33. Martin, K. H., Slack, J. K., Boemer, S. A., Martin, C. C. and Parsons, J. T. Integrin connections map: to infinity and beyond. Science296 (2002) l652-l653.
34. Gilmore, A. P. and Romer, L. H. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Cell. Biol. 7 (1997) 1209-1224.
35. Gohbovskaya, V., Kaur, A. and Cance, W. Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites. Biochim. Biophys. Acta1678 (2004) 11-25.
36. Post, G. R. and Brown, J. H. G protein-coupled receptors and signaling pathways regulating growth responses. FASEB J. 10 (1996) 741-749.
37. Fukuhara, Y., Hirasawa, A., Li, X. K., Kawasaki, M., Fujino, M. and Funeshima, N. Gene expression profile in the regenerating rat liver after partial hepatectomy. J. Hepatol. 38 (2003) 784-792.
38. Reissig, D., Clement, J., Sänger, J., Berndt, A., Kosmehl, H. and Böhmer, F. D. Elevated activity and expression of Src-family kinases in human breast carcinoma tissue versus matched no tumor tissue. J. Cancer Res. Clin. Oncol. 127 (2001) 226-230.
39. Biscardi, J. S., Ishizawar, R. C., Silva, C. M. and Parsons, S. J. Tyrosine kinase signaling in breast cancer: epidermal growth f actor receptor and c- Src interactions in breast cancer. Breast Cancer Res. 2 (2002) 203-210.
40. Xu, C. S., Chang, C. F., Yuan, J. Y., Li, W. Q., Han, H. P. and Yang, K. J. Expressed genes in regenerating rat liver after partial hepatectomy. World J. Gastroenterol. 11 (2005) 2932-2940.
41. Michalopoulos, G. K. and DeFrances, M. Liver regeneration. Adv. Biochem. Eng. Biotechnol. 93 (2005) 101-134.