Epstein-barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties

Journal of Biological Chemistry

Volumn 287, Issue 32, 2012, Pages 26586-26595

  Yoon, Sung Il ^a,b,c   Jones, Brandi C ^b   Logsdon, Naomi J ^b   Harris, Bethany D ^b   Kuruganti, Srilalitha ^a   Walter, Mark R ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c Kangwon National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY PROFILE; BINDING AFFINITIES; CELL LINES; CELL SURFACE RECEPTORS; CELLULAR PROLIFERATIONS; CHIMERIC PROTEINS; CYTOKINES; EPSTEIN-BARR VIRUS; IMMUNE RESPONSE; INTERLEUKIN-10; KINETIC ANALYSIS; PROLIFERATIVE ACTIVITY; RECEPTOR BINDING; TWO-STEP MECHANISMS;

BINDING ENERGY; CELL CULTURE; CELL MEMBRANES; CELL PROLIFERATION; DIMERS; VIRUSES;

SCAFFOLDS (BIOLOGY);

INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CELL ACTIVITY; CELL LEVEL; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; EPSTEIN BARR VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DIMERIZATION; DROSOPHILA; HERPESVIRUS 4, HUMAN; INTERLEUKIN-10; INTERLEUKIN-10 RECEPTOR ALPHA SUBUNIT; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

HUMAN HERPESVIRUS 4;

EID: 84864554412     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.376707     Document Type: Article

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