Comparison of in vivo selection and rational design of heterodimeric coiled coils

Structure

Volumn 10, Issue 9, 2002, Pages 1235-1248

  Arndt, Katja M ^a,b   Pelletier, Joelle N ^b   Müller, Kristian M ^a   Plückthun, Andreas ^b   Alber, Tom ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Coiled coil; Leucine zipper; Library selection; PCA; Protein design; Protein engineering; Protein protein interactions

Indexed keywords

AMINO ACID; ION; DIHYDROFOLATE REDUCTASE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; CELL LINE; DIMERIZATION; ELECTRICITY; GENETIC SELECTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; THERMODYNAMICS; CELL CULTURE; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; COMPARATIVE STUDY; DIRECTED MOLECULAR EVOLUTION; DRUG DESIGN; ENZYME STABILITY; HYDROGEN BOND; KINETICS; METABOLISM; PROTEIN ENGINEERING; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TEMPERATURE;

CELL DIVISION; CELLS, CULTURED; CIRCULAR DICHROISM; DIMERIZATION; DIRECTED MOLECULAR EVOLUTION; DRUG DESIGN; ELECTROSTATICS; ENZYME STABILITY; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; PROTEIN ENGINEERING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE; TETRAHYDROFOLATE DEHYDROGENASE; THERMODYNAMICS;

EID: 0036710244     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00838-9     Document Type: Article

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