A single amino acid determines the immunostimulatory activity of interleukin 10

Journal of Experimental Medicine

Volumn 191, Issue 2, 2000, Pages 213-223

  Ding, Yaozhong ^a,b   Qin, Lihui ^b   Kotenko, Serguci V ^c   Pestka, Sidney ^c   Bromberg, Jonathan S ^a,b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Affinity; Interleukin 10; Signaling; Stimulation; Suppression

Indexed keywords

ALANINE; AMINO ACID; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; ISOLEUCINE; LEUCINE;

ANTIGENICITY; ARTICLE; EPSTEIN BARR VIRUS; GENE MUTATION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNE RESPONSE; IMMUNOSTIMULATION; LIGAND BINDING; MAST CELL; PRIORITY JOURNAL; THYMOCYTE; VIRUS PATHOGENESIS;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CELL DIVISION; CELLS, CULTURED; CHO CELLS; COS CELLS; CRICETINAE; DNA-BINDING PROTEINS; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-10; ISOLEUCINE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MILK PROTEINS; MOLECULAR SEQUENCE DATA; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-10; SEQUENCE HOMOLOGY, AMINO ACID; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

EID: 0034677006     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.2.213     Document Type: Article

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