Thymosin beta 4 protects cardiomyocytes from oxidative stress by targeting anti-oxidative enzymes and anti-apoptotic genes

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Wei, Chuanyu ^a   Kumar, Sandeep ^a   Kim, Il Kwon ^a   Gupta, Sudhiranjan ^a  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; THYMOSIN BETA4;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CATALASE GENE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CU ZN SOD GENE; DRUG TARGETING; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HEART INJURY; HEART MUSCLE CELL; HEART PROTECTION; MN SOD GENE; NF KAPPAB GENE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; QUANTITATIVE STUDY; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSLATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; CYTOPROTECTION; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MYOCYTES, CARDIAC; NF-KAPPA B; NITRIC OXIDE; OXIDATIVE STRESS; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE; SUPEROXIDES; THYMOSIN; UP-REGULATION;

RATTUS;

EID: 84864546575     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042586     Document Type: Article

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