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Volumn 385, Issue 8, 2012, Pages 759-767

Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3- adrenoceptor agonist KUC-7322

Author keywords

3 Adrenoceptor; Human detrusor; KUC 7322; Relaxation

Indexed keywords

1 (2 ETHYLPHENOXY) 3 (1,2,3,4 TETRAHYDRO 1 NAPHTHYLAMINO) 2 PROPANOL OXALATE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR; CARBACHOL; CLENBUTEROL; FORSKOLIN; ISOPRENALINE; KUC 7322; UNCLASSIFIED DRUG;

EID: 84864464187     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0763-x     Document Type: Article
Times cited : (27)

References (44)
  • 2
    • 34147121696 scopus 로고    scopus 로고
    • Relaxation of human detrusor muscle by selective beta-2 and beta-3 agonists and endogenous catecholamines
    • DOI 10.1016/j.urology.2007.01.059, PII S0090429507001252
    • Badawi JK, Seja T, Uecelehan H, Honeck P, Kwon S-T, Bross S, Langbein S (2007) Relaxation of human detrusor muscle by selective beta-2 and beta-3 agonists and endogenous catecholamines. Urology 69:785-790 (Pubitemid 46574943)
    • (2007) Urology , vol.69 , Issue.4 , pp. 785-790
    • Badawi, J.K.1    Seja, T.2    Uecelehan, H.3    Honeck, P.4    Kwon, S.-T.5    Bross, S.6    Langbein, S.7
  • 3
    • 14644421602 scopus 로고    scopus 로고
    • The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors
    • DOI 10.1038/sj.bjp.0706048
    • Baker JG (2005) The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br J Pharmacol 144:317-322 (Pubitemid 40313677)
    • (2005) British Journal of Pharmacology , vol.144 , Issue.3 , pp. 317-322
    • Baker, J.G.1
  • 4
    • 77953185520 scopus 로고    scopus 로고
    • The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptors
    • Baker JG (2010) The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptors. Br J Pharmacol 160:1048-1061
    • (2010) Br J Pharmacol , vol.160 , pp. 1048-1061
    • Baker, J.G.1
  • 6
    • 33750891388 scopus 로고    scopus 로고
    • 3-adrenoceptor agonist (GW427353) on spontaneous activity and detrusor relaxation in human bladder
    • DOI 10.1111/j.1464-410X.2006.06564.x
    • Biers SM, Reynard JM, Brading AF (2006) The effects of a new selective β3-adrenoceptor agonist (GW427353) on spontaneous activity and detrusor relaxation in human bladder. BJU Int 98:1310-1314 (Pubitemid 44721248)
    • (2006) BJU International , vol.98 , Issue.6 , pp. 1310-1314
    • Biers, S.M.1    Reynard, J.M.2    Brading, A.F.3
  • 8
    • 33745698250 scopus 로고    scopus 로고
    • Effects of gender, age and hypertension on β-adrenergic receptor function in rat urinary bladder
    • DOI 10.1007/s00210-006-0077-y
    • Fazier EP, Schneider T, Michel MC (2006) Effects of gender, age and hypertension on β-adrenergic receptor function in rat urinary bladder. Naunyn-Schmiedeberg's Arch Pharmacol 373:300-309 (Pubitemid 43999781)
    • (2006) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.373 , Issue.4 , pp. 300-309
    • Frazier, E.P.1    Schneider, T.2    Michel, M.C.3
  • 13
    • 1442349847 scopus 로고    scopus 로고
    • Comparative pharmacology of human β-adrenergic receptor subtypes - Characterization of stably transfected receptors in CHO cells
    • DOI 10.1007/s00210-003-0860-y
    • Hoffmann C, LeitzMR, Oberdorf-Maass S, Lohse MJ, Klotz K-N (2004) Comparative pharmacology of human β-adrenergic receptor subtypes- characterization of stably transfected receptors in CHOcells. Naunyn-Schmiedeberg's Arch Pharmacol 369:151-159 (Pubitemid 38270770)
    • (2004) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.369 , Issue.2 , pp. 151-159
    • Hoffmann, C.1    Leitz, M.R.2    Oberdorf-Maass, S.3    Lohse, M.J.4    Klotz, K.-N.5
  • 17
    • 0034749291 scopus 로고    scopus 로고
    • Relaxant effects of isoproterenol and selective β3-adrenoceptor agonists on normal, low compliant and hyperreflexic human bladders
    • Igawa Y, Yamazaki Y, Takeda H, Kaidoh K, Akahane M, Ajisawa Y, Yoneyama T, Nishizawa O, Andersson KE (2001) Relaxant effects of isoproterenol and selective β3-adrenoceptor agonists on normal, low compliant and hyperreflexic human bladders. J Urol 165:240-244
    • (2001) J Urol , vol.165 , pp. 240-244
    • Igawa, Y.1    Yamazaki, Y.2    Takeda, H.3    Kaidoh, K.4    Akahane, M.5    Ajisawa, Y.6    Yoneyama, T.7    Nishizawa, O.8    Andersson, K.E.9
  • 18
    • 60949111457 scopus 로고    scopus 로고
    • Potentiation of carbachol-induced detrusor smooth muscle contractions by β- adrenoceptor activation
    • Klausner AP, Rourke KF, Miner AS, Ratz PH (2009) Potentiation of carbachol-induced detrusor smooth muscle contractions by β- adrenoceptor activation. Eur J Pharmacol 606:191-198
    • (2009) Eur J Pharmacol , vol.606 , pp. 191-198
    • Klausner, A.P.1    Rourke, K.F.2    Miner, A.S.3    Ratz, P.H.4
  • 20
    • 0345328601 scopus 로고    scopus 로고
    • Age-dependent changes in β-adrenoceptor function in human detrusors and possible mechanisms
    • Li G, Li K, Wang P (2003) Age-dependent changes in β-adrenoceptor function in human detrusor and possible mechanisms. Chin Med J 116:1511-1514 (Pubitemid 37461667)
    • (2003) Chinese Medical Journal , vol.116 , Issue.10 , pp. 1511-1514
    • Li, G.1    Li, K.2    Li, Z.3    Wang, P.4
  • 21
    • 79952339400 scopus 로고    scopus 로고
    • β-Adrenoceptor-mediated differences in transverse and longitudinal strips from the rat detrusor
    • Liang W, Lo WN (2011) β-Adrenoceptor-mediated differences in transverse and longitudinal strips from the rat detrusor. Int Urol Nephrol 43:99-107
    • (2011) Int Urol Nephrol , vol.43 , pp. 99-107
    • Liang, W.1    Lo, W.N.2
  • 22
  • 23
    • 71249116156 scopus 로고    scopus 로고
    • Effect of pre-contraction on β- adrenoceptor-mediated relaxation of rat urinary bladder
    • Michel MC, Sand C (2009) Effect of pre-contraction on β- adrenoceptor-mediated relaxation of rat urinary bladder. World J Urol 27:711-715
    • (2009) World J Urol , vol.27 , pp. 711-715
    • Michel, M.C.1    Sand, C.2
  • 24
    • 79952488799 scopus 로고    scopus 로고
    • Desirable properties of β3-adrenoceptor agonists : Implications for the selection of drug development candidates
    • Michel MC, Cernecka H, Ochodnicky P (2011a) Desirable properties of β3-adrenoceptor agonists : Implications for the selection of drug development candidates. Eur J Pharmacol 657:1-3
    • (2011) Eur J Pharmacol , vol.657 , pp. 1-3
    • Michel, M.C.1    Cernecka, H.2    Ochodnicky, P.3
  • 25
    • 79956202487 scopus 로고    scopus 로고
    • β- Adrenoceptor agonist effects in experimental models of bladder dysfunction
    • Michel MC, Ochodnicky P, Homma Y, Igawa Y (2011b) β- Adrenoceptor agonist effects in experimental models of bladder dysfunction. Pharmacol Ther 131:40-49
    • (2011) Pharmacol Ther , vol.131 , pp. 40-49
    • Michel, M.C.1    Ochodnicky, P.2    Homma, Y.3    Igawa, Y.4
  • 26
    • 0033625191 scopus 로고    scopus 로고
    • 3-adrenoceptors in rat, rabbit and human urinary bladder and external urethral sphincter
    • Morita T, Iizuka H, Iwata T, Kondo S (2000) Function and distribution of β3-adrenoceptors in rat, rabbit, and human urinary bladder and external urethral sphincter. J Smooth Muscle Res 36:21-32 (Pubitemid 30365869)
    • (2000) Journal of Smooth Muscle Research , vol.36 , Issue.1 , pp. 21-32
    • Morita, T.1    Iizuka, H.2    Iwata, T.3    Kondo, S.4
  • 27
    • 33846917217 scopus 로고    scopus 로고
    • The role of the urothelium in mediating bladder responses to isoprenaline
    • DOI 10.1111/j.1464-410X.2006.06679.x
    • Murakami S, Chapple CR, Akino H, Sellers DJ, Chess-Williams R (2007) The role of the urothelium in mediating bladder responses to isoprenaline. BJU Int 99:669-673 (Pubitemid 46238848)
    • (2007) BJU International , vol.99 , Issue.3 , pp. 669-673
    • Murakami, S.1    Chapple, C.R.2    Akino, H.3    Sellers, D.J.4    Chess-Williams, R.5
  • 28
    • 0017365232 scopus 로고
    • Characterization of the adrenergic β-receptor in the urinary bladder of man and cat
    • Nergardh A, Boreus LO, Naglo AS (1978) Characterization of the adrenergic β-receptor in the urinary bladder of man and cat. Acta Pharmacol Toxicol 40:14-21
    • (1978) Acta Pharmacol Toxicol , vol.40 , pp. 14-21
    • Nergardh, A.1    Boreus, L.O.2    Naglo, A.S.3
  • 30
    • 0037830662 scopus 로고    scopus 로고
    • A quantitative analysis of mRNA expression of α1 and β-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders
    • Nomiya M, Yamaguchi O (2003) A quantitative analysis of mRNA expression of a1 and β-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders. J Urol 170:649-653 (Pubitemid 36870277)
    • (2003) Journal of Urology , vol.170 , Issue.I2 , pp. 649-653
    • Nomiya, M.1    Yamaguchi, O.2
  • 32
    • 57449097188 scopus 로고    scopus 로고
    • Effects of a novel β3-adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle : An in vitro study
    • Otsuka A, Shinbo H, Hasebe K, Matsumoto R, Ozono S (2008a) Effects of a novel β3-adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle : An in vitro study. Int J Urol 15:1072-1076
    • (2008) Int J Urol , vol.15 , pp. 1072-1076
    • Otsuka, A.1    Shinbo, H.2    Hasebe, K.3    Matsumoto, R.4    Ozono, S.5
  • 35
    • 21844441901 scopus 로고    scopus 로고
    • A role for the P2X receptor in urinary tract physiology and in the pathophysiology of urinary dysfunction
    • DOI 10.1016/j.eururo.2005.04.019, PII S0302283805002629
    • Rapp DE, Lyon MB, Bales GT, Cook SP (2005) A role for the P2X receptor in urinary tract physiology and in the pathophysiology of urinary dysfunction. Eur Urol 48:303-308 (Pubitemid 40957109)
    • (2005) European Urology , vol.48 , Issue.2 , pp. 303-308
    • Rapp, D.E.1    Lyon, M.B.2    Bales, G.T.3    Cook, S.P.4
  • 36
    • 35548946776 scopus 로고    scopus 로고
    • Ligand-directed signaling at the β3-adrenoceptor produced by SR59230A relative to receptor agonists
    • Sato M, Horinouchi T, Hutchinson DS, Evans BA, Summers RJ (2007) Ligand-directed signaling at the β3-adrenoceptor produced by SR59230A relative to receptor agonists. Mol Pharmacol 74:1359-1368
    • (2007) Mol Pharmacol , vol.74 , pp. 1359-1368
    • Sato, M.1    Horinouchi, T.2    Hutchinson, D.S.3    Evans, B.A.4    Summers, R.J.5
  • 38
    • 79956218124 scopus 로고    scopus 로고
    • Human urinary bladder strip relaxation by the β-adrenoceptor agonist isoprenaline : Methodological considerations and effects of gender and age
    • Schneider T, Fetscher C, Michel MC (2011) Human urinary bladder strip relaxation by the β-adrenoceptor agonist isoprenaline : Methodological considerations and effects of gender and age. Frontiers Pharmacol 2:11
    • (2011) Frontiers Pharmacol , vol.2 , pp. 11
    • Schneider, T.1    Fetscher, C.2    Michel, M.C.3
  • 41
    • 65549144124 scopus 로고    scopus 로고
    • Do gene polymorphisms alone or in combination affect the function of human β3-adrenoceptors?
    • Vrydag W, Alewijnse AE, Michel MC (2009) Do gene polymorphisms alone or in combination affect the function of human β3-adrenoceptors? Br J Pharmacol 156:127-134
    • (2009) Br J Pharmacol , vol.156 , pp. 127-134
    • Vrydag, W.1    Alewijnse, A.E.2    Michel, M.C.3
  • 44
    • 33750633989 scopus 로고    scopus 로고
    • 3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro
    • DOI 10.1002/nau.20231
    • Yamanishi T, Yasuda K, Kitahara S, Nakai H, K-i Y, Iizuka H (2006) Effects of 138-355, a β3-adrenoceptor selective agonist, on relaxation of the human detrusor muscle in vitro. Neurourol Urodyn 25:815-819 (Pubitemid 44691390)
    • (2006) Neurourology and Urodynamics , vol.25 , Issue.7 , pp. 815-819
    • Yamanishi, T.1    Yasuda, K.2    Kitahara, S.3    Nakai, H.4    Yoshida, K.-I.5    Iizuka, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.