Functional dissection of Nrf2-dependent phase II genes in vascular inflammation and endotoxic injury using Keap1 siRNA

Free Radical Biology and Medicine

Volumn 53, Issue 3, 2012, Pages 629-640

  Kim, Ji Hee ^a   Choi, Yoon Kyung ^a   Lee, Kwang Soon ^a   Cho, Dong Hui ^a   Baek, Yi Yong ^a   Lee, Dong Keon ^a   Ha, Kwon Soo ^a   Choe, Jongseon ^a   Won, Moo Ho ^a   Jeoung, Dooil ^a   Lee, Hansoo ^a   Kwon, Young Guen ^b   Kim, Young Myeong ^a  

^a Kangwon National University   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Free radicals; Inflammation; Keap1; NF B; Nrf2; Phase II gene

Indexed keywords

HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NITRIC OXIDE SYNTHASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME MICRODISSECTION; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LETHALITY; LIVER INJURY; LUNG INJURY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPSIS; SEPTIC SHOCK; UPREGULATION; VASCULAR DISEASE; VASCULITIS;

ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; CELL ADHESION; CELL ADHESION MOLECULES; CELLS, CULTURED; CYTOPROTECTION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; LIVER; LUNG; MACROPHAGES; MALE; METABOLIC DETOXICATION, PHASE II; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PEROXIREDOXINS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULITIS;

EID: 84864459993     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.04.019     Document Type: Article

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