4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-κB-DNA-binding activity

European Journal of Pharmacology

Volumn 551, Issue 1-3, 2006, Pages 143-151

  Lee, Gwangsoo ^a   Na, Hee Jun ^a   Namkoong, Seung ^a   Jeong Kwon, Ho ^b   Han, Sanghwa ^a   Ha, Kwon Soo ^a   Kwon, Young Guen ^b   Lee, Hansoo ^a   Kim, Young Myeong ^a  

^a Kangwon National University   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

4 O methylgallic acid; Endothelial cell; ICAM 1; NF B; VCAM 1

Indexed keywords

4 O METHYLGALLIC ACID; CELL ADHESION MOLECULE; DITHIOTHREITOL; DNA; DRUG METABOLITE; GALLIC ACID DERIVATIVE; I KAPPA B KINASE; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; NITRIC OXIDE; OLIGONUCLEOTIDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOSOL; DRUG ACTIVITY; DRUG DNA BINDING; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RED WINE; UMBILICAL VEIN;

ANTI-INFLAMMATORY AGENTS; ATHEROSCLEROSIS; CELL ADHESION; CELL ADHESION MOLECULES; CELLS, CULTURED; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIAL CELLS; GALLIC ACID; GENES, REPORTER; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; LUCIFERASES; NF-KAPPA B; NITRIC OXIDE; PROMOTER REGIONS (GENETICS); REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 33750479072     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.08.061     Document Type: Article

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